Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claire E. Walters"'
Autor:
Samuel McLenachan, Nancy R. Nichols, Claire E. Walters, Ann M. Turnley, Martin J. Stebbing, Hannah J. Scott, Mark I. Ransome
Publikováno v:
Brain Research. 1067:138-145
Neuronal differentiation of neural progenitor cells is regulated by a variety of growth and transcription factors, that not only regulate cell fate of the progenitor cells but that can also regulate neuronal morphology. Suppressor of cytokine signali
Autor:
Claire E. Walters, Claire Amos, John Greenwood, Peter Adamson, Pierre-Olivier Couraud, Ruth Lyck, Britta Engelhardt
Publikováno v:
The Journal of Immunology. 171:2099-2108
To examine the role of the ICAM-1 C-terminal domain in transendothelial T lymphocyte migration and ICAM-1-mediated signal transduction, mutant human (h)ICAM-1 molecules were expressed in rat brain microvascular endothelial cells. The expression of wi
Autor:
John Greenwood, David Baker, Andrew D. Hamilton, Claire E. Walters, Deborah J.R. Hankey, Said M. Sebti, Peter Adamson, Gareth Pryce
Publikováno v:
The Journal of Immunology. 168:4087-4094
The ICAM-1-mediated brain endothelial cell (EC)-signaling pathway induced by adherent lymphocytes is a central element in facilitating lymphocyte migration through the tight endothelial barrier of the brain. Rho proteins, which must undergo posttrans
Publikováno v:
NeuroReport. 10:1699-1705
Addition of the beta-hydroxy-beta-methylglutaryl-CoA (HmG-CoA) reductase inhibitor lovastatin to human HEK cells transfected with the amyloid precursor protein (APP) reduces intracellular cholesterol/protein ratios by 50%, and markedly inhibits beta-
Autor:
P. Nagesh Rao, Mark J. Pettenati, Fong-Fong Chu, H.A.Rohan de Silva, Claire E. Walters, Allen D. Roses, Kalina K. Boteva, R. Steven Esworthy
Publikováno v:
Genomics. 32:272-276
We have isolated a 3.3-kb DNA containing the two exons and a 2.6-kb intron of the humanGPX2gene. This gene encodes the intestinal isoenzyme of glutathione peroxidase, GSHPx-GI. Consistent signals were detected at 14q24.1 when this DNA was used as a p
Autor:
Ann M. Turnley, Hannah J. Scott, Claire E. Walters, Yona Goldshmit, Christopher J. Greenhalgh
Publikováno v:
The Journal of biological chemistry. 279(16)
Suppressor of cytokine signaling (SOCS) 2 is a negative regulator of growth hormone (GH) signaling that regulates body growth postnatally and neuronal differentiation during development. SOCS2 binds to the GH receptor and inhibits GH signaling, inclu
Autor:
Naheed Kanuga, John Greenwood, Claire E. Walters, Evelyne Beraud, Peter Adamson, David Baker, Gareth Pryce
Publikováno v:
Scopus-Elsevier
Neuroinflammatory diseases, such as multiple sclerosis (MS), result from aberrant leukocyte traffic into the central nervous system (CNS). To breach the specialized blood-brain barrier, activated leukocytes interact with CNS endothelial cells (EC) an