Výsledky vyhledávání - "Claire E. Segar"

Abstract 107: SPADE Analysis Reveals The Recruitment Of Rare Immune Cell Subtypes To Site Of Injury Following Treatment With Immunomodulatory Hydrogels

Autor: Nusaiba Baker, Claire McClain, Mary Caitlin P. Sok, Edward A. Botchwey, L. A. Hymel, Hong Seo Lim, Claire E. Segar, Peng Qiu, Molly E. Ogle, Thomas C. Turner, Andrés J. García

Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 70-71 (2020)
Plastic and Reconstructive Surgery Global Open

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b290652b577c90b64d227a33efa32b
http://journals.lww.com/prsgo/fulltext/10.1097/01.GOX.0000667484.70881.69

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Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design

Autor: Edward A. Botchwey, Claire E. Segar, Molly E. Ogle, Sraeyes Sridhar

Publikováno v: Experimental Biology and Medicine. 241:1084-1097

Monocytes and macrophages play a critical role in tissue development, homeostasis, and injury repair. These innate immune cells participate in guiding vascular remodeling, stimulation of local stem and progenitor cells, and structural repair of tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7ccc2b3b139423d039ff1af007ceb5
https://doi.org/10.1177/1535370216650293

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Spatially localized recruitment of anti-inflammatory monocytes by SDF-1α-releasing hydrogels enhances microvascular network remodeling

Autor: Jennifer McFaline-Figueroa, Molly E. Ogle, Claire E. Segar, Johnna S. Temenoff, Jack R. Krieger, Edward A. Botchwey

Publikováno v: Biomaterials. 77:280-290

Tissue repair processes are characterized by the biphasic recruitment of distinct subpopulations of blood monocytes, including classical ("inflammatory") monocytes (IMs, Ly6C(hi)Gr1(+)CX3CR1(lo)) and non-classical anti-inflammatory monocytes (AMs, Ly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0e575101d16b764ba2b53e49a99e28
https://doi.org/10.1016/j.biomaterials.2015.10.045

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Long-term culture of HL-1 cardiomyocytes in modular poly(ethylene glycol) microsphere-based scaffolds crosslinked in the phase-separated state

Autor: Amanda W. Smith, Igor R. Efimov, Matthew R. MacEwan, Claire E. Segar, Peter K. Nguyen, Donald L. Elbert

Publikováno v: Acta Biomaterialia. 8:31-40

Poly(ethylene glycol) (PEG) microspheres were assembled around HL-1 cardiomyocytes to produce highly porous modular scaffolds. In this study, we took advantage of the immiscibility of PEG and dextran to improve upon our previously described modular s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312b2febe2b50cb6c05a3da7e19e6090
https://doi.org/10.1016/j.actbio.2011.08.021

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Bioactive lipid coating of bone allografts directs engraftment and fate determination of bone marrow-derived cells in rat GFP chimeras

Autor: Yihsuan Chu, Tiffany Wang, Xeujun Du, Claire E. Segar, Quanjun Cui, Roy C. Ogle, Edward A. Botchwey, Yong Lin, Anusuya Das, Chunxi Yang

Publikováno v: Biomaterials. 64

Bone grafting procedures are performed to treat wounds incurred during wartime trauma, accidents, and tumor resections. Endogenous mechanisms of repair are often insufficient to ensure integration between host and donor bone and subsequent restoratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef4269597a7dabdfb90d86f796d87f1
https://pubmed.ncbi.nlm.nih.gov/26125501

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The promotion of mandibular defect healing by the targeting of S1P receptors and the recruitment of alternatively activated macrophages

Autor: Claire E. Segar, Brian B. Hughley, Daniel T. Bowers, Anusuya Das, Edward A. Botchwey

Endogenous signals originating at the site of injury are involved in the paracrine recruitment, proliferation, and differentiation of circulating progenitor and diverse inflammatory cell types. Here, we investigate a strategy to exploit endogenous ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429622314bd8efab53afbec42f8580b7
https://europepmc.org/articles/PMC3797185/

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Regulation of angiogenesis and bone regeneration with natural and synthetic small molecules

Autor: Edward A. Botchwey, Molly E. Ogle, Claire E. Segar

Publikováno v: Current pharmaceutical design. 19(19)

Regeneration of bone requires the coordinated processes of angiogenesis and osteogenesis. These repair mechanisms are closely linked through both direct cell-cell contact and indirect paracrine signaling among osteoblasts, endothelial cells, and othe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb817267bb8f8332696148327b18b016
https://pubmed.ncbi.nlm.nih.gov/23432670

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