Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Claire E. Naylor"'
Autor:
David R. Lisgarten, Rex A. Palmer, Jon B. Cooper, Claire E. Naylor, Rosemary C. Talbert, Brendan J. Howlin, John N. Lisgarten, Janez Konc, Shabir Najmudin, Carina M. C. Lobley
Publikováno v:
BMC Chemistry, Vol 17, Iss 1, Pp 1-30 (2023)
Abstract The crystal structure of orthorhombic Bovine Pancreatic Ribonuclease A has been determined to 0.85 Å resolution using low temperature, 100 K, synchrotron X-ray data collected at 16000 keV (λ = 0.77 Å). This is the first ultra-high-resolut
Externí odkaz:
https://doaj.org/article/c3e000059a4646ef998bd30012666b7f
Autor:
Christos G. Savva, Alice R. Clark, Claire E. Naylor, Michel R. Popoff, David S. Moss, Ajit K. Basak, Richard W. Titball, Monika Bokori-Brown
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Epsilon toxin (Etx) is a potent pore forming toxin (PFT) produced by Clostridium perfringens. Here authors show the cryo-EM structure of the Etx pore assembled on the membrane of susceptible cells and shed light on pore formation and mutant phenotype
Externí odkaz:
https://doaj.org/article/0c3cc9c7ec024b4ca980cfc36be9bbed
Autor:
David R. Lisgarten, Rex A. Palmer, Carina M. C. Lobley, Claire E. Naylor, Babur Z. Chowdhry, Zakieh I. Al-Kurdi, Adnan A. Badwan, Brendan J. Howlin, Nicholas C. J. Gibbons, José W. Saldanha, John N. Lisgarten, Ajit K. Basak
Publikováno v:
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-26 (2017)
Abstract The crystal structure of a commercially available form of human recombinant (HR) insulin, Insugen (I), used in the treatment of diabetes has been determined to 0.92 Å resolution using low temperature, 100 K, synchrotron X-ray data collected
Externí odkaz:
https://doaj.org/article/2546e37de46f402693f6c4df8de106fa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure
Externí odkaz:
https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1
Autor:
Monika Bokori-Brown, Thomas G. Martin, Claire E. Naylor, Ajit K. Basak, Richard W. Titball, Christos G. Savva
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Lysenin is member of the aerolysin family of small ß-barrel pore-forming toxins that include virulence factors from several human and animal pathogens. Here the authors determine the structure of the lysenin pore by single particle cryo- EM and prop
Externí odkaz:
https://doaj.org/article/b12960b2d8de44f388f6f4d400e7f3cc
Autor:
Sérgio P. Fernandes da Costa, Christos G. Savva, Monika Bokori-Brown, Claire E. Naylor, David S. Moss, Ajit K. Basak, Richard W. Titball
Publikováno v:
Toxins, Vol 6, Iss 3, Pp 1049-1061 (2014)
Necrotic enteritis toxin B (NetB) is a β-pore-forming toxin produced by Clostridium perfringens and has been identified as a key virulence factor in the pathogenesis of avian necrotic enteritis, a disease causing significant economic damage to the p
Externí odkaz:
https://doaj.org/article/f70777b14f5141aa8f86f4369883e9a8
Autor:
David. R Lisgarten, Rex. A Palmer, Jon Cooper, Claire. E Naylor, Rosemary. C Talbert, Brenden. J Howlin, John. N Lisgarten, Janez. Konc, Shabir. Najmudin, Carina. M.C. Lobley
The crystal structure of orthorhombic Bovine Pancreatic Ribonuclease A has been determined to 0.85Å resolution using low temperature, 100K, synchrotron X-ray data collected at 16000keV (λ = 0.77Å). This is the first ultra-high-resolution structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2693b101ab2a8698a75f7a714be78a36
https://doi.org/10.21203/rs.3.rs-2852137/v1
https://doi.org/10.21203/rs.3.rs-2852137/v1
Autor:
Cristina Cecchetti, Edward Pryor, Simon Tanley, Adrian Goldman, Bernadette Byrne, Claire E. Naylor, Jannik Strauss, Claudia Stohrer, Jeanette Hobbs
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254118 (2021)
PLoS ONE
PLOS ONE
PLoS ONE
PLOS ONE
Membrane proteins have a range of crucial biological functions and are the target of about 60% of all prescribed drugs. For most studies, they need to be extracted out of the lipid-bilayer, e.g. by detergent solubilisation, leading to the loss of nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ff2b40c0b01a384e07edb3697e9678
https://doaj.org/article/22e197f755e54af484c0e5dea3a85437
https://doaj.org/article/22e197f755e54af484c0e5dea3a85437
Autor:
Claire E. Naylor, Leo C. T. Ng, Bonnie A. Wallace, Altin Sula, Paul G. DeCaen, Jennifer Booker
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications
'Nature Communications ', vol: 8, pages: 14205-1-14205-9 (2017)
Nature Communications
'Nature Communications ', vol: 8, pages: 14205-1-14205-9 (2017)
Voltage-gated sodium channels (Navs) play essential roles in excitable tissues, with their activation and opening resulting in the initial phase of the action potential. The cycling of Navs through open, closed and inactivated states, and their close
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3b5c5f8eac2ea779cb8157f5d9ac40
https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1
https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1
Autor:
Marietta Flores-Díaz, Claire E. Naylor, Antje Flieger, Alberto Alape-Girón, Laura Monturiol-Gross
Publikováno v:
Microbiology and Molecular Biology Reviews, vol. 80(3) pp. 597-628
Kérwá
Universidad de Costa Rica
instacron:UCR
Kérwá
Universidad de Costa Rica
instacron:UCR
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze sphingomyelin and glyceropho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e651f563179315436011c11c0134b73a
https://doi.org/10.1128/mmbr.00082-15
https://doi.org/10.1128/mmbr.00082-15