Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Claire E. Madden"'
Autor:
Andrew Parker, Jakob Sloth, Clive J. Roberts, Claire E. Madden-Smith, Nikin Patel, Jesper Jensen, Paul T. Whiteside, Jianxin Zhang
Publikováno v:
International Journal of Pharmaceutics. 455:306-311
When assessing the suitability of potential drug/polymer systems for improving drug bioavailability, substantial efficiency gains can be achieved through the development and application of rapid miniaturised screening methods. For this to be possible
Autor:
Claire E. Madden-Smith, Matthew Bunker, Nikin Patel, Jianxin Zhang, Clive J. Roberts, Andrew Parker
Publikováno v:
International Journal of Pharmaceutics. 414:210-217
Nanothermal analysis (NTA) supported by atomic force microscopy imaging has been used to study the changes that occur at the surfaces of solid dispersions of the drug felodipine and the water soluble polymer, polyvinylpyrrolidone (PVP) on exposure to
Autor:
Robert E. Johnson, Claire E. Madden-Smith, Delphine Le Roux, Saleem S. Ahmed, Dirk L. Teagarden, David O. Bates, S Rigby-Singleton, Lavinia M. Lewis, Mark Perkins, Andrew Parker, Clive J. Roberts
Publikováno v:
Journal of Pharmaceutical Sciences. 99:4616-4629
This work investigated the impact of primary drying conditions on the microstructure and protein stability of bovine serum albumin (BSA) containing lyophilized cakes. Two primary drying conditions were employed (termed ‘conservative’, slower dryi
Autor:
Nikin Patel, S Rigby-Singleton, Claire E. Madden-Smith, Jeff James, J. Ledru, Shen Y. Luk, Clive J. Roberts, Mark Perkins, Matt Bunker
Publikováno v:
European Journal of Pharmaceutical Sciences. 38:1-8
In this study we aim to explore the potential links between the mechanical properties, micronisation behaviour and surface energy of carbamazepine polymorphs using atomic force microscopy (AFM) measurements of material properties at the nanoscale. Ca
Autor:
Michael W. George, Nikin Patel, Paul Turner, Shen Y. Luk, Claire E. Madden-Smith, Paul T. Whiteside
Publikováno v:
Pharmaceutical Research. 25:2650-2656
To demonstrate the potential of monitoring H/D exchange by FT-Raman spectroscopy as a tool for the detection and quantification of low levels of amorphous lactose in formulations.Samples containing different proportions of amorphous and crystalline l
Publikováno v:
Colloid and Polymer Science. 283:1108-1115
Well-defined dispersions of polydivinylbenzene in methanol and a binary liquid mixture of methanol and water were stabilised by samples of partially hydrolysed poly(vinyl alcohol) (PVOH). Mean particle diameters in the range 0.3–1.0 μm were produc
Publikováno v:
Journal of Cultural Heritage. 4:271-275
A significant issue in the current research on laser cleaning studies is the discoloration effect that the laser radiation may cause to many medieval pigments. Towards a thorough study of this effect, specially prepared limestone plates coated with l
Publikováno v:
New Journal of Chemistry. 26:259-263
Horse spleen ferritin is a naturally occurring iron storage protein, consisting of a protein shell encapsulating a hydrous ferric oxide core about 8 nm in diameter. It is known from prior work that the protein can be adsorbed onto the surface of tin-
Publikováno v:
The Analyst. 126:1878-1881
Nanocomposite electrodes offer exciting new possibilities in electroanalytical chemistry. In this preliminary study, nanocomposite electrodes made of carbon nanofibers and black wax were characterized and investigated as novel substrates for metal de
Autor:
Katherine B. Holt, Mark L. Gerrard, Ian Mellor, Roger J. Mortimer, John S. Foord, Frank Page, Stephen Fletcher, Frank Marken, Ralf H. Dahm, Claire E. Madden
Publikováno v:
Electrochemistry Communications, Vol 3, Iss 4, Pp 177-180 (2001)
Carbon nanofibers with diameters in the range 10-500 nm have been evaluated as novel electrode materials for electrochemical applications. Compared with other forms of nanostructured carbons, such as aerogels or activated charcoal, carbon nanofibers