Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Claire E. Council"'
Autor:
Kristian Hollingsworth, Antonio Di Maio, Sarah-Jane Richards, Jean-Baptiste Vendeville, David E. Wheatley, Claire E. Council, Tessa Keenan, Hélène Ledru, Harriet Chidwick, Kun Huang, Fabio Parmeggiani, Andrea Marchesi, Wengang Chai, Ryan McBerney, Tomasz P. Kamiński, Matthew R. Balmforth, Alexandra Tamasanu, James D. Finnigan, Carl Young, Stuart L. Warriner, Michael E. Webb, Martin A. Fascione, Sabine Flitsch, M. Carmen Galan, Ten Feizi, Matthew I. Gibson, Yan Liu, W. Bruce Turnbull, Bruno Linclau
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Glycan-mediated interactions play a crucial role in biology and medicine, influencing signalling, immune responses, and disease pathogenesis. However, the use of glycans in biosensing and diagnostics is limited by cross-reactivity, as certai
Externí odkaz:
https://doaj.org/article/45fc41374e2f4ce2b12a1822076a1c13
Autor:
P. Patrizia Mangione, Stéphanie Deroo, Stephan Ellmerich, Vittorio Bellotti, Simon Kolstoe, Stephen P. Wood, Carol V. Robinson, Martin D. Smith, Glenys A. Tennent, Robert J. Broadbridge, Claire E. Council, Joanne R. Thurston, Victoria A. Steadman, Antonio K. Vong, Christopher J. Swain, Mark B. Pepys, Graham W. Taylor
Publikováno v:
Open Biology, Vol 5, Iss 9 (2015)
Wild-type and variant forms of transthyretin (TTR), a normal plasma protein, are amyloidogenic and can be deposited in the tissues as amyloid fibrils causing acquired and hereditary systemic TTR amyloidosis, a debilitating and usually fatal disease.
Externí odkaz:
https://doaj.org/article/92a745814544494abf587c612d2605eb
Autor:
Sarah-Jane Richards, Tessa Keenan, Jean-Baptiste Vendeville, David E. Wheatley, Harriet Chidwick, Darshita Budhadev, Claire E. Council, Claire S. Webster, Helene Ledru, Alexander N. Baker, Marc Walker, M. Carmen Galan, Bruno Linclau, Martin A. Fascione, Matthew I. Gibson
Publikováno v:
Chemical Science
Galectins are potential biomarkers and therapeutic targets. However, galectins display broad affinity towards β-galactosides meaning glycan-based (nano)biosensors lack the required selectivity and affinity. Using a polymer-stabilized nanoparticle bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6155232c787d2ca8b60f42cec68871aa
https://doi.org/10.1039/d0sc05360k
https://doi.org/10.1039/d0sc05360k
Autor:
Claire E. Council, Kelly J. Kilpin, Jessica S. Gusthart, Sarah A. Allman, Bruno Linclau, Seung Seo Lee
Publikováno v:
Organic & Biomolecular Chemistry. 18:3423-3451
Fluorinated carbohydrates, where one (or more) fluorine atom(s) have been introduced into a carbohydrate structure, typically through deoxyfluorination chemistry, have a wide range of applications in the glycosciences. Fluorinated derivatives of gala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686db9f3697f4665f0062631581424ab
https://doi.org/10.1039/d0ob00436g
https://doi.org/10.1039/d0ob00436g
Autor:
John, Butler, Neil, Smyth, Robert, Broadbridge, Claire E, Council, Anthony G, Lee, Claire J, Stocker, David C, Hislop, Jonathan R S, Arch, Michael A, Cawthorne, J, Malcolm East
Publikováno v:
Archives of Biochemistry and Biophysics
Highlights • Sarcolipin is insufficient to affect thermogenic activity of SERCA in mouse muscle. • The ratio of SLN to SERCA in total limb skeletal muscle is
Studies in sarcolipin knockout mice have led to the suggestion that skeletal muscle
Studies in sarcolipin knockout mice have led to the suggestion that skeletal muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de7a06dfe2852b1c60780119a6efeb91
https://pubmed.ncbi.nlm.nih.gov/25660043
https://pubmed.ncbi.nlm.nih.gov/25660043