Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Claire E. Allen"'
Autor:
Marc M. J. Da Costa, Claire E. Allen, Adrian Higginbottom, Tennore Ramesh, Pamela J. Shaw, Christopher J. McDermott
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 1, Pp 73-81 (2014)
Mutations in the superoxide dismutase gene (SOD1) are one cause of familial amyotrophic lateral sclerosis [ALS; also known as motor neuron disease (MND)] in humans. ALS is a relentlessly progressive neurodegenerative disease and, to date, there are n
Externí odkaz:
https://doaj.org/article/afaa7493008d4a99a31fa7bd68eff1c7
Genetic engineering techniques have rapidly developed since the first large-scale forward genetics screen was developed in 1996, which generated a spectrum of phenotypic zebrafish lines with mutations in many essential genes for normal development. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62bcd736dbd94162db6f5f53b14e340
https://hdl.handle.net/11577/3471382
https://hdl.handle.net/11577/3471382
Publikováno v:
The Journal of Physiology. 594:5427-5438
Hair cells are sensory receptors responsible for transducing auditory and vestibular information into electrical signals, which are then transmitted with remarkable precision to afferent neurons. The zebrafish lateral line is emerging as an excellent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0480da603910cfcfe709aec340c7e71f
https://doi.org/10.1113/jp271794
https://doi.org/10.1113/jp271794
Publikováno v:
The International Journal of Developmental Biology. 53:45-57
The Hedgehog (Hh) family of signalling molecules is essential for a wide range of developmental processes. Mammalian studies have implicated the Hedgehog pathway in the aetiology of anorectal malformations (ARMs), relatively common congenital anomali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2206435b61f2fbeac684328fa1e14421
https://doi.org/10.1387/ijdb.082669cp
https://doi.org/10.1387/ijdb.082669cp
Autor:
Claire E. Allen, Helen I. Woodroof, Aimee McTighe, Miratul M. K. Muqit, Rosemarie Soellner, Reinhard W. Köster, Heather Mortiboys, Philip W. Ingham, Marcus Keatinge, Paul R. Heath, Laura J. Flinn, Andreas S. Reichert, Lucy M. Brown, Sandrine Bretaud, Hideaki Matsui, Elena De Felice, Oliver Bandmann, Marta Milo
Publikováno v:
Annals of Neurology
Autosomal recessively inherited, loss of function mutations in PTEN‐induced kinase 1 (PINK1) typically lead to early onset Parkinson disease (EOPD).1 The PINK1 protein is expressed ubiquitously throughout the human brain.2 Impaired mitochondrial fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e720104adeaf75289299c08269cbcbe
http://hdl.handle.net/11581/405383
http://hdl.handle.net/11581/405383
Autor:
José L. Juárez-Morales, Katharine E. Lewis, Claus J. Schulte, Claire E. Allen, Samantha J. England
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 240(5)
The transcription factor Evx1 is expressed in the joints between individual lepidotrichia (bony ray) segments and at the distal tips of the lepidotrichia in developing zebrafish fins. It is also expressed in the apical growth zone in regenerating fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac465b16b347ecf55c6a46598f58a5a5
https://pubmed.ncbi.nlm.nih.gov/21509898
https://pubmed.ncbi.nlm.nih.gov/21509898
Publikováno v:
Journal of neurochemistry. 100(6)
Mutations in DJ-1 lead to early onset Parkinson's disease (PD). The aim of this study was to elucidate further the underlying mechanisms leading to neuronal cell death in DJ-1 deficiency in vivo and determine whether the observed cell loss could be p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951587b6320475a3dcb1766ceb3a1887
https://pubmed.ncbi.nlm.nih.gov/17166173
https://pubmed.ncbi.nlm.nih.gov/17166173
Publikováno v:
Mechanisms of Development. 126:S227-S228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb143c33eb4ad0f1b06c8f79c4bbf47