Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Claire E Turner"'
Autor:
Jessica E Buddle, Lucy M Thompson, Anne S Williams, Rosanna C T Wright, William M Durham, Claire E Turner, Roy R Chaudhuri, Michael A Brockhurst, Robert P Fagan
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002741 (2024)
Clostridioides difficile is an important human pathogen, for which there are very limited treatment options, primarily the glycopeptide antibiotic vancomycin. In recent years, vancomycin resistance has emerged as a serious problem in several gram-pos
Externí odkaz:
https://doaj.org/article/53a85d31ba3c433588634f1cb67da377
Autor:
Erin A. Catton, Daniel A. Bonsor, Carolina Herrera, Margaretha Stålhammar-Carlemalm, Mykola Lyndin, Claire E. Turner, Jo Soden, Jos A. G. van Strijp, Bernhard B. Singer, Nina M. van Sorge, Gunnar Lindahl, Alex J. McCarthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis, resulted in classical epidemics and remain a global health problem. While outbreaks of puerperal sepsis have been ascribed to Streptococcus pyogenes,
Externí odkaz:
https://doaj.org/article/5a23515633f34b6aa094d200181feb31
Autor:
Luke R. Green, Rahaf Issa, Fawzyah Albaldi, Lucy Urwin, Ruth Thompson, Henna Khalid, Claire E. Turner, Barbara Ciani, Lynda J. Partridge, Peter N. Monk
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Epithelial colonization is a critical first step in bacterial pathogenesis. Staphylococcus aureus can utilize several host factors to associate with cells, including α5β1 integrin and heparan sulfate proteoglycans, such as the syndecans. H
Externí odkaz:
https://doaj.org/article/5d075cea95f446b7b507d17006be5322
Autor:
Saikou Y. Bah, Alexander J. Keeley, Edwin P. Armitage, Henna Khalid, Roy R. Chaudhuri, Elina Senghore, Jarra Manneh, Lisa Tilley, Michael Marks, Saffiatou Darboe, Abdul K. Sesay, Thushan I. de Silva, Claire E. Turner
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT Streptococcus pyogenes is a leading cause of human morbidity and mortality, especially in resource-limited settings. The development of a vaccine against S. pyogenes is a global health priority to reduce the burden of postinfection rheumatic
Externí odkaz:
https://doaj.org/article/777bbb6398cb4b4ebf4d266b1482a0aa
Autor:
Isatou Jagne, Alexander J. Keeley, Abdoulie Bojang, Bully Camara, Edrissa Jallow, Elina Senghore, Claire Oluwalana, Saikou Y. Bah, Claire E. Turner, Abdul Karim Sesay, Umberto D’Alessandro, Christian Bottomley, Thushan I. de Silva, Anna Roca
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Group A Streptococcus (GAS) is a major human pathogen and an important cause of maternal and neonatal sepsis. Asymptomatic bacterial colonization is considered a necessary step towards sepsis. Intra-partum azithromycin may reduce
Externí odkaz:
https://doaj.org/article/aa0e286fe3dc4a29b44a705370f71d78
Autor:
Erin A. Catton, Daniel A. Bonsor, Carolina Herrera, Margaretha Stålhammar-Carlemalm, Mykola Lyndin, Claire E. Turner, Jo Soden, Jos A. G. van Strijp, Bernhard B. Singer, Nina M. van Sorge, Gunnar Lindahl, Alex J. McCarthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7b74b7bc3db94478be60184ee0e25fbb
Autor:
Lionel K. K. Tan, Mark Reglinski, Daryl Teo, Nada Reza, Lucy E. M. Lamb, Vaitehi Nageshwaran, Claire E. Turner, Mats Wikstrom, Inga-Maria Frick, Lars Bjorck, Shiranee Sriskandan
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or va
Externí odkaz:
https://doaj.org/article/445c3bbbceec45f2be2bdc2c075e8bd3
Autor:
Matthew K. Siggins, Nicola N. Lynskey, Lucy E. Lamb, Louise A. Johnson, Kristin K. Huse, Max Pearson, Suneale Banerji, Claire E. Turner, Kevin Woollard, David G. Jackson, Shiranee Sriskandan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Pathogenic agents can spread from an initial to a secondary site via the lymphatics. Here, using a mouse model of infection, the authors show that S. pyogenes readily transit through sequential lymph nodes within efferent lymphatics to reach the bloo
Externí odkaz:
https://doaj.org/article/82442a72732d4568ad2c06ae269341a8
Autor:
Claire E. Turner, Matthew T. G. Holden, Beth Blane, Carolyne Horner, Sharon J. Peacock, Shiranee Sriskandan
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Gene transfer and homologous recombination in Streptococcus pyogenes has the potential to trigger the emergence of pandemic lineages, as exemplified by lineages of emm1 and emm89 that emerged in the 1980s and 2000s, respectively. Although ne
Externí odkaz:
https://doaj.org/article/d9a74542681e4998a1112583d95db004
Autor:
Hema Sharma, Claire E. Turner, Matthew K. Siggins, Mona El-Bahrawy, Bruno Pichon, Angela Kearns, Shiranee Sriskandan
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Nonmenstrual toxic shock syndrome (nmTSS), linked to TSST-1-producing CC30 Staphylococcus aureus, is the leading manifestation of toxic shock syndrome (TSS). Due to case rarity and a lack of tractable animal models, TSS pathogenesis is poorl
Externí odkaz:
https://doaj.org/article/82173a6aae1d488ab7997188d3224846