Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Claire E Lewis"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The paradigm for macrophage characterization has evolved from the simple M1/M2 dichotomy to a more complex model that encompasses the broad spectrum of macrophage phenotypic diversity, due to differences in ontogeny and/or local stimuli. We
Externí odkaz:
https://doaj.org/article/269cfff46f0a40a6876c6588d0c9c2bc
Autor:
Christopher Bailey, Johann De Bono, Munitta Muthana, Mateus Crespo, Bora Gurel, Pasquale Rescigno, Matthew Fisher, Wayne A Phillips, Richard Allen, Harry Nunns, Janet E Brown, Haider Al-janabi, Katy Moyes, Anna Junker-Jensen, Helen B Pearson, Mary-Ellen Taplin, Claire E Lewis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Androgen deprivation therapy (ADT) is a front-line treatment for prostate cancer. In some men, their tumors can become refractory leading to the development of castration-resistant prostate cancer (CRPC). This causes tumors to regrow and m
Externí odkaz:
https://doaj.org/article/2f9585a571b74710badae3f4850ddc0f
Autor:
Roberto Pili
Publikováno v:
JNCI Journal of the National Cancer Institute. 90:1169-1170
Autor:
Munitta Muthana, Joe Conner, Sarah J. Danson, Janet E. Brown, Claire E. Lewis, Graham Pockley, Jayakumar Vadakekolathu, Penelope Ottewell, Sanjay Srivastava, Simon J. Tazzyman, Taewoo Kim, Adam Wilshaw, Joshua Handley, Katie Cox, Drew Capper, Matthew Hutchinson, Dhanajay Evans, Rikah Louie, Mohammed Moamin, Russell Hughes, Richard J. Allen, Haider Al-Janabi, Emer Atkinson, Natalie Winder, Amy Kwan
Supplementary Tables and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a95db13d525e2373f8c7096de989a19
https://doi.org/10.1158/1535-7163.22521123
https://doi.org/10.1158/1535-7163.22521123
Autor:
Claire E. Lewis, Yvonne Reiss, Karl H. Plate, Craig Murdoch, Subhra K. Biswas, Carmen Urbich, Sunil Patel, Michele De Palma, Alexander Scholz, Andrea O. Tal, Seth B. Coffelt
TIE2-expressing monocytes/macrophages (TEM) are a highly proangiogenic subset of myeloid cells in tumors. Here, we show that circulating human TEMs are already preprogrammed in the circulation to be more angiogenic and express higher levels of such p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e85e2021e3d09bf23502327a5fd2d230
https://doi.org/10.1158/0008-5472.c.6500303
https://doi.org/10.1158/0008-5472.c.6500303
Autor:
Claire E. Lewis, Fiona Morrow, Magnus Essand, Simon Tazzyman, Russell Hughes, Abigail Welford, Yung-Yi Chen, Samuel Rodrigues, Munitta Muthana
PDF file - 68K, Presence of OV in lungs of mice bearing human prostate (LNCaP-LUC) tumors after docetaxel treatment or irradiation followed by macrophage delivery of OV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423a1c833ecfe2c8dcb7f0e1cef65753
https://doi.org/10.1158/0008-5472.22396089.v1
https://doi.org/10.1158/0008-5472.22396089.v1
Autor:
Norman J. Maitland, Claire E. Lewis, Magnus Essand, Peter Hoskin, Lindsay Georgopoulos, Nicola J. Brown, Freddie Hamdy, Roshna Mistry, Bernard Burke, Neil Cross, Julian Burton, Craig Murdoch, Fiona J. Morrow, Seth B. Coffelt, Hsin-Yu Fang, Simon D. Scott, Athina Giannoudis, Munitta Muthana
Supplementary Figure 3 from Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3226003384928403e39093d34dcb2e95
https://doi.org/10.1158/0008-5472.22389795.v1
https://doi.org/10.1158/0008-5472.22389795.v1
Autor:
Norman J. Maitland, Claire E. Lewis, Magnus Essand, Peter Hoskin, Lindsay Georgopoulos, Nicola J. Brown, Freddie Hamdy, Roshna Mistry, Bernard Burke, Neil Cross, Julian Burton, Craig Murdoch, Fiona J. Morrow, Seth B. Coffelt, Hsin-Yu Fang, Simon D. Scott, Athina Giannoudis, Munitta Muthana
Supplementary Figure 1 from Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4f75aa4804513fd090a26c07fba929
https://doi.org/10.1158/0008-5472.22389801
https://doi.org/10.1158/0008-5472.22389801
Autor:
Claire E. Lewis, Fiona Morrow, Magnus Essand, Simon Tazzyman, Russell Hughes, Abigail Welford, Yung-Yi Chen, Samuel Rodrigues, Munitta Muthana
PDF file - 454K, Macrophage delivery of an oncolytic virus (Ad1/PPT-E1A) abolishes the regrowth of human prostate (LUC-LNCaP) tumors after treatment with the cytotoxic agent, docetaxel (DOX)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1619f3675f223fecdd6cbb4e2adce63
https://doi.org/10.1158/0008-5472.22396095.v1
https://doi.org/10.1158/0008-5472.22396095.v1
Autor:
Norman J. Maitland, Claire E. Lewis, Magnus Essand, Peter Hoskin, Lindsay Georgopoulos, Nicola J. Brown, Freddie Hamdy, Roshna Mistry, Bernard Burke, Neil Cross, Julian Burton, Craig Murdoch, Fiona J. Morrow, Seth B. Coffelt, Hsin-Yu Fang, Simon D. Scott, Athina Giannoudis, Munitta Muthana
New therapies are required to target hypoxic areas of tumors as these sites are highly resistant to conventional cancer therapies. Monocytes continuously extravasate from the bloodstream into tumors where they differentiate into macrophages and accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df761423e6859701e3d7474c1c6f1619
https://doi.org/10.1158/0008-5472.c.6502722.v1
https://doi.org/10.1158/0008-5472.c.6502722.v1