Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Claire E, Hills"'
Autor:
Elena Roger, Christos E. Chadjichristos, Panagiotis Kavvadas, Gareth W. Price, Chelsy L. Cliff, Safia Hadjadj, Jessy Renciot, Paul E. Squires, Claire E. Hills
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types. Activated in response to danger
Externí odkaz:
https://doaj.org/article/e48577cddf834d8685f737c5c38985e6
Autor:
Gareth W. Price, Christos E. Chadjichristos, Panagiotis Kavvadas, Sydney C. W. Tang, Wai Han Yiu, Colin R. Green, Joe A. Potter, Eleftherios Siamantouras, Paul E. Squires, Claire E. Hills
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Tubulointerstitial fibrosis represents the key underlying pathology of Chronic Kidney Disease (CKD), yet treatment options remain limited. In this study, we investigated the role of connexin43 (Cx43) hemichannel-mediated adenosine
Externí odkaz:
https://doaj.org/article/cbf3b5a17eb140fdbcaac434c1479c5c
Autor:
Chelsy L. Cliff, Bethany M. Williams, Christos E. Chadjichristos, Ulrik Mouritzen, Paul E. Squires, Claire E. Hills
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 600 (2022)
Of increasing prevalence, diabetes is characterised by elevated blood glucose and chronic inflammation that precedes the onset of multiple secondary complications, including those of the kidney and the eye. As the leading cause of end stage renal dis
Externí odkaz:
https://doaj.org/article/5488b82fc47c4609b76a49db29ce70cb
Autor:
Eleftherios Siamantouras, Charlie Woodrow, Emine Celiker, Darron A. Cullen, Claire E. Hills, Paul E. Squires, Fernando Montealegre-Z
Publikováno v:
Acta Biomaterialia. 153:399-410
Derived from the respiratory tracheae, bush-crickets' acoustic tracheae (or ear canals) are hollow tubes evolved to transmit sounds from the external environment to the interior ear. Due to the location of the ears in the forelegs, the acoustic trach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cc4bf68c8d5cb46a85413aba997fc9
https://doi.org/10.1016/j.actbio.2022.08.056
https://doi.org/10.1016/j.actbio.2022.08.056
Autor:
Paul E. Squires, Gareth W. Price, Ulrik Mouritzen, Joe A. Potter, Bethany M. Williams, Claire E. Hills
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2809 (2021)
Chronic kidney disease (CKD) is a global health problem associated with a number of comorbidities. Recent evidence implicates increased hemichannel-mediated release of adenosine triphosphate (ATP) in the progression of tubulointerstitial fibrosis, th
Externí odkaz:
https://doaj.org/article/8e95d8a526234043bb974ca2ff600f5f
Autor:
Joe A. Potter, Gareth W. Price, Chelsy L. Cliff, Colin R. Green, Paul E. Squires, Claire E. Hills
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3644 (2021)
Chronic Kidney Disease (CKD) is associated with sustained inflammation and progressive fibrosis, changes that have been linked to altered connexin hemichannel-mediated release of adenosine triphosphate (ATP). Kidney fibrosis develops in response to i
Externí odkaz:
https://doaj.org/article/61f93d00866e49918fb1c4ba26845bd4
Autor:
Shanta J, Persaud, Claire E, Hills
Publikováno v:
Diabetic Medicine. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007d68ecb694efbc936b1e9737908e7d
https://doi.org/10.1111/dme.14990
https://doi.org/10.1111/dme.14990
Introduction: Fibrosis of renal tubules is the final common pathway in diabetic nephropathy and develops in the face of tubular injury and fibroblast activation. Aberrant connexin 43 (Cx43) hemichannel activity has been linked to this damage under eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dc3ce717fc7d82e8e9cf44873810d5
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 5, Pp 1200-1212 (2013)
Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexin-mediated intercellular communication in proximal tubule-derived epithelial cells. Methods: The effects of visfatin (10-200ng/mL) on cell viability and c
Externí odkaz:
https://doaj.org/article/f77a76a2689143749b5c4978a4754c28
Autor:
Bethany M Williams, Gareth Price, Paul E. Squires, Joe A. Potter, Chelsy L. Cliff, Claire E. Hills
Publikováno v:
Experimental Physiology. 105:219-229
The ability of cells to communicate and synchronise their activity is essential for the maintenance of tissue structure, integrity and function. A family of membrane-bound proteins called connexins are largely responsible for mediating the local tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86519122dca8563e9c3a2afb72275b4
https://doi.org/10.1113/ep087770
https://doi.org/10.1113/ep087770