Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Claire Dunn"'
Autor:
Sudhir Kumar Chauhan, Claire Dunn, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Gjertrud Skorstad, Adam Sike, Bjørnar Gilje, Sunil Xavier Raj, Kanutte Huse, Bjørn Naume, Jon Amund Kyte
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Immunotherapies blocking the PD-1/PD-L1 checkpoint show some efficacy in metastatic breast cancer (mBC) but are often hindered by immunosuppressive mechanisms. Understanding these mechanisms is crucial for personalized treatments, with perip
Externí odkaz:
https://doaj.org/article/21138a5be7fa4ef6868ac4e8d5f2a5bf
Autor:
Ragnhild Sørum Falk, Bjornar Gilje, Andrea Gombos, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Claire Quaghebeur, Beate Boge, Randi R. Mathiesen, Lars Julsrud, Øystein Garred, Hege G. Russnes, Ragnhild Reehorst Lereim, Sudhir Kumar Chauhan, Ole Christian Lingjærde, Claire Dunn, Bjørn Naume, Jon Amund Kyte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Immune checkpoint inhibitors have shown minimal clinical activity in hormone receptor-positive metastatic breast cancer (HR+mBC). Doxorubicin and low-dose cyclophosphamide are reported to induce immune responses and counter regulatory T ce
Externí odkaz:
https://doaj.org/article/e9ba64ad31414caeaea3d72626619d91
Autor:
Yixin Jin, Claire Dunn, Irene Persiconi, Adam Sike, Gjertrud Skorstad, Carole Beck, Jon Amund Kyte
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 586 (2024)
We have developed a chimeric antigen receptor (CAR) against the six-transmembrane epithelial antigen of prostate-1 (STEAP1), which is expressed in prostate cancer, Ewing sarcoma, and other malignancies. In the present study, we investigated the effec
Externí odkaz:
https://doaj.org/article/a629e6a06cd2429d8ab78ab7f593e619
Autor:
Yixin Jin, Kristina Berg Lorvik, Yang Jin, Carole Beck, Adam Sike, Irene Persiconi, Emilie Kvaløy, Fahri Saatcioglu, Claire Dunn, Jon Amund Kyte
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 189-206 (2022)
Chimeric antigen receptors (CARs) that retarget T cells against CD19 show clinical efficacy against B cell malignancies. Here, we describe the development of a CAR against the six-transmembrane epithelial antigen of prostate-1 (STEAP1), which is expr
Externí odkaz:
https://doaj.org/article/78ece43bd6684e589e295a37b73f23e1
Autor:
Claire Dunn, Isabel Laterzo
Publikováno v:
Journal of Politics in Latin America, Vol 13 (2021)
In Brazil and Mexico, presidents failed to take swift, national action to stop the spread of COVID-19. Instead, the burden of imposing and enforcing public health measures has largely fallen to subnational leaders, resulting in varied approaches with
Externí odkaz:
https://doaj.org/article/bbc79aad199341d0b49c300d84f5adf3
Autor:
Esmaeil Dorraji, Elin Borgen, Dario Segura-Peña, Puneet Rawat, Eva Smorodina, Claire Dunn, Victor Greiff, Nikolina Sekulić, Hege Russnes, Jon Amund Kyte
Publikováno v:
Cancers, Vol 14, Iss 19, p 4859 (2022)
The expression of human epidermal growth factor receptor 2 (HER2) is a key classification factor in breast cancer. Many breast cancers express isoforms of HER2 with truncated carboxy-terminal fragments (CTF), collectively known as p95HER2. A common p
Externí odkaz:
https://doaj.org/article/fdcf156c92a84e1eaadd3170a7c54e87
Autor:
Christian Klein, Inja Waldhauer, Valeria G. Nicolini, Anne Freimoser-Grundschober, Tapan Nayak, Danielle J. Vugts, Claire Dunn, Marije Bolijn, Jörg Benz, Martine Stihle, Sabine Lang, Michaele Roemmele, Thomas Hofer, Erwin van Puijenbroek, David Wittig, Samuel Moser, Oliver Ast, Peter Brünker, Ingo H. Gorr, Sebastian Neumann, Maria Cristina de Vera Mudry, Heather Hinton, Flavio Crameri, Jose Saro, Stefan Evers, Christian Gerdes, Marina Bacac, Guus van Dongen, Ekkehard Moessner, Pablo Umaña
Publikováno v:
OncoImmunology, Vol 6, Iss 3 (2017)
We developed cergutuzumab amunaleukin (CEA-IL2v, RG7813), a novel monomeric CEA-targeted immunocytokine, that comprises a single IL-2 variant (IL2v) moiety with abolished CD25 binding, fused to the C-terminus of a high affinity, bivalent carcinoembry
Externí odkaz:
https://doaj.org/article/a319ded80cfa47ca96224b37437a82ff
Autor:
Dimitra Peppa, Lorenzo Micco, Alia Javaid, Patrick T F Kennedy, Anna Schurich, Claire Dunn, Celeste Pallant, Gidon Ellis, Pooja Khanna, Geoffrey Dusheiko, Richard J Gilson, Mala K Maini
Publikováno v:
PLoS Pathogens, Vol 6, Iss 12, p e1001227 (2010)
NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill
Externí odkaz:
https://doaj.org/article/ffd688712266402aa9a1b4de8190e233
Autor:
Isabel Laterzo, Claire Dunn
Publikováno v:
Journal of Politics in Latin America, Vol 13 (2021)
In Brazil and Mexico, presidents failed to take swift, national action to stop the spread of COVID-19. Instead, the burden of imposing and enforcing public health measures has largely fallen to subnational leaders, resulting in varied approaches with
Autor:
Claire Dunn
Publikováno v:
Publius: The Journal of Federalism. 52:283-309
What role do subnational governments play in shaping a country’s redistributive efforts? Existing literature suggests that federalism can be a hindrance to redistribution. Such negative effects may be particularly true of Latin America’s federati