Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Claire Duff"'
Autor:
Andrea Frassetto, Julien Baruteau, Lisa Rice, Paolo G.V. Martini, Alex Cavedon, Summar Siddiqui, Neil Sebire, Patrick F Finn, Claire Duff, Garima Sharma, Sonam Gurung, Loukia Touramanidou, Dany Perocheau
Publikováno v:
F1000Research, Vol 12 (2024)
Background In academic research and the pharmaceutical industry, in vitro cell lines and in vivo animal models are considered as gold standards in modelling diseases and assessing therapeutic efficacy. However, both models have intrinsic limitations,
Externí odkaz:
https://doaj.org/article/f300c8c9470e494e8be8d47def6c31a2
Autor:
Claire Duff, Madeha Islam, Onelia Gagliano, Hema Pramod, Hassan Rashidi, Manju Kurian, Paul Gissen, Julien Baruteau
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103365- (2024)
Argininosuccinic aciduria (ASA) is a rare inherited metabolic disease caused by argininosuccinate lyase (ASL) deficiency. Patients with ASA present with hyperammonaemia due to an impaired urea cycle pathway in the liver, and systemic disease with epi
Externí odkaz:
https://doaj.org/article/d3fd767ff3ea4c0fb07289f442e5f9bd
Autor:
Claire Duff, Julien Baruteau
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract The urea cycle is a liver-based pathway enabling disposal of nitrogen waste. Urea cycle disorders (UCDs) are inherited metabolic diseases caused by deficiency of enzymes or transporters involved in the urea cycle and have a prevalence of 1:3
Externí odkaz:
https://doaj.org/article/102d60ad66214f22b286647e9bdcb583
Autor:
Agata Wesolowska-Andersen, Rikke Rejnholdt Jensen, Marta Pérez Alcántara, Nicola L. Beer, Claire Duff, Vibe Nylander, Matthew Gosden, Lorna Witty, Rory Bowden, Mark I. McCarthy, Mattias Hansson, Anna L. Gloyn, Christian Honore
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 138-153 (2020)
Summary: Several distinct differentiation protocols for deriving pancreatic progenitors (PPs) from human pluripotent stem cells have been described, but it remains to be shown how similar the PPs are across protocols and how well they resemble their
Externí odkaz:
https://doaj.org/article/b60c4c2dbd8f46aabd5388e20bd4b931
Autor:
Sofia Christakoudi, Manohursingh Runglall, Paula Mobillo, Tjir-Li Tsui, Claire Duff, Clara Domingo-Vila, Yogesh Kamra, Florence Delaney, Rosa Montero, Anastasia Spiridou, Theodoros Kassimatis, Sui Phin-Kon, Beatriz Tucker, Christopher Farmer, Terry B. Strom, Graham M. Lord, Irene Rebollo-Mesa, Daniel Stahl, Steven Sacks, Maria P. Hernandez-Fuentes, Paramit Chowdhury
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 571-583 (2019)
Background: Acute T-cell mediated rejection (TCMR) is usually indicated by alteration in serum-creatinine measurements when considerable transplant damage has already occurred. There is, therefore, a need for non-invasive early detection of immune si
Externí odkaz:
https://doaj.org/article/dbd47bb0ad88471a9010ab59f2dad071
Autor:
Dany Perocheau, Sonam Gurung, Loukia Touramanidou, Claire Duff, Garima Sharma, Neil Sebire, Patrick F. Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G.V. Martini, Andrea Frassetto, Julien Baruteau
In academic research and the pharmaceutical industry,in vitrosingle cell line cultures andin vivoanimal models are considered as gold standards in modelling diseases and assessing therapeutic efficacy. However, both models have limitations, with inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788c3af6ae22dc0abf9e4d2bdc288e67
https://doi.org/10.1101/2023.03.23.533840
https://doi.org/10.1101/2023.03.23.533840
Autor:
Steven H. Sacks, Clara Domingo-Vila, Terry B. Strom, Florence Delaney, Claire Duff, Manohursingh Runglall, Paula Mobillo, Tjir Li Tsui, Rosa Montero, Sui Phin-Kon, Maria P. Hernandez-Fuentes, Yogesh Kamra, Anastasia Spiridou, Paramit Chowdhury, Graham M. Lord, Irene Rebollo-Mesa, Sofia Christakoudi, Daniel Stahl, Theodoros Kassimatis, Christopher K.T. Farmer, Beatriz Tucker
Publikováno v:
EBioMedicine
EBioMedicine, Vol 41, Iss, Pp 571-583 (2019)
Christakoudi, S, Runglall, M, Mobillo, P, Tsui, T L, Duff, C, Domingo-Vila, C, Kamra, Y, Delaney, F, Montero, R, Spiridou, A, Kassimatis, T, Phin-Kon, S, Tucker, B, Farmer, C, Strom, T B, Lord, G M, Rebollo-Mesa, I, Stahl, D, Sacks, S, Hernandez-Fuentes, M P & Chowdhury, P 2019, ' Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples ', EBioMedicine, vol. 41, pp. 571-583 . https://doi.org/10.1016/j.ebiom.2019.01.060
Christakoudi, S, Runglall, M, Mobillo, P A, Tsui, T-L, Duff, C, Domingo Vila, C, Kamra, Y K, Delaney, F, Montero, R, Spiridou, A, Kassimatis, T, Phin Kon, S, Tucker, B, Farmer, C, Strom, T B, Lord, G M, Rebollo-Mesa, I, Stahl, D, Sacks, S, Hernandez-Fuentes, M P & Chowdhury, P 2019, ' Development of a multivariable geneexpression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in crosssectional and longitudinal samples ', EBioMedicine, vol. 41, no. 0, pp. 571-583 . https://doi.org/10.1016/j.ebiom.2019.01.060
EBioMedicine, Vol 41, Iss, Pp 571-583 (2019)
Christakoudi, S, Runglall, M, Mobillo, P, Tsui, T L, Duff, C, Domingo-Vila, C, Kamra, Y, Delaney, F, Montero, R, Spiridou, A, Kassimatis, T, Phin-Kon, S, Tucker, B, Farmer, C, Strom, T B, Lord, G M, Rebollo-Mesa, I, Stahl, D, Sacks, S, Hernandez-Fuentes, M P & Chowdhury, P 2019, ' Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples ', EBioMedicine, vol. 41, pp. 571-583 . https://doi.org/10.1016/j.ebiom.2019.01.060
Christakoudi, S, Runglall, M, Mobillo, P A, Tsui, T-L, Duff, C, Domingo Vila, C, Kamra, Y K, Delaney, F, Montero, R, Spiridou, A, Kassimatis, T, Phin Kon, S, Tucker, B, Farmer, C, Strom, T B, Lord, G M, Rebollo-Mesa, I, Stahl, D, Sacks, S, Hernandez-Fuentes, M P & Chowdhury, P 2019, ' Development of a multivariable geneexpression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in crosssectional and longitudinal samples ', EBioMedicine, vol. 41, no. 0, pp. 571-583 . https://doi.org/10.1016/j.ebiom.2019.01.060
Background Acute T-cell mediated rejection (TCMR) is usually indicated by alteration in serum-creatinine measurements when considerable transplant damage has already occurred. There is, therefore, a need for non-invasive early detection of immune sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae24299bfbd3674285318dfe252d4a2a
http://europepmc.org/articles/PMC6441872
http://europepmc.org/articles/PMC6441872
Autor:
Björn Holst, Mikkel Rasmussen, Christian Honore, Christian Clausen, Max Jansen, Claire Duff, Mark I. McCarthy, Anna L. Gloyn, Antje Grotz, Agata Wesolowska-Andersen, Nicole A.J. Krentz, Mattias Hansson, Rikke Rejnholdt Jensen, Marta Perez-Alcantara
Publikováno v:
Diabetes. 69
Heterozygous loss of function mutations in HNF1A, encoding the transcription factor hepatocyte nuclear factor 1 alpha (HNF-1A) are the most common cause of monogenic diabetes. HNF-1A is involved in both beta cell development and mature cell function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06cbfd669c3a9d21a6aaab68221af1d5
https://doi.org/10.2337/db20-2050-p
https://doi.org/10.2337/db20-2050-p