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pro vyhledávání: '"Claire C. Milton"'
Supplementary Figure 2 from Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b426ea520c9d7776506d0bb416f457
https://doi.org/10.1158/0008-5472.22379511.v1
https://doi.org/10.1158/0008-5472.22379511.v1
Supplementary Materials and Methods from Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4cb27f37860bb644bf254037105f6d
https://doi.org/10.1158/0008-5472.22379508.v1
https://doi.org/10.1158/0008-5472.22379508.v1
Supplementary Figure 1 from Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4111d0793751de84b7f22050176158
https://doi.org/10.1158/0008-5472.22379514.v1
https://doi.org/10.1158/0008-5472.22379514.v1
Publikováno v:
PLoS ONE, Vol 1, p e75 (2006)
Partial reduction of Hsp90 increases expression of morphological novelty in qualitative traits of Drosophila and Arabidopsis, but the extent to which the Hsp90 chaperone also controls smaller and more likely adaptive changes in natural quantitative t
Externí odkaz:
https://doaj.org/article/844cfb8e89a5448a8c3bacf0d6f5c9df
Autor:
Kieran F. Harvey, Qi Dai, Felix A. Grusche, Eefang Yu, Joffrey L. Degoutin, Eric C. Lai, Claire C. Milton
Publikováno v:
Current Biology. 24:2673-2680
SummaryThe Salvador-Warts-Hippo (Hippo) pathway is an evolutionarily conserved regulator of organ growth and cell fate. It performs these functions in epithelial and neural tissues of both insects and mammals, as well as in mammalian organs such as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876b91644f3d8c11c39909eeb690a89f
https://doi.org/10.1016/j.cub.2014.10.031
https://doi.org/10.1016/j.cub.2014.10.031
Publikováno v:
Cancer Research. 69:6033-6041
The Salvador/Warts/Hippo (SWH) pathway is an important modulator of organ size, and deregulation of pathway activity can lead to cancer. Several SWH pathway components are mutated or expressed at altered levels in different human tumors including NF2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f222ab55ce4f1dab933b6ca3c15333
https://doi.org/10.1158/0008-5472.can-08-4592
https://doi.org/10.1158/0008-5472.can-08-4592
Autor:
Louise Toft Jensen, Carla M. Sgrò, Phil Batterham, Claire C. Milton, Ary A. Hoffmann, Volker Loeschcke, Jane Frydenberg
Publikováno v:
Sgrò, C M, Milton, C C, Jensen, L T, Frydenberg, J, Loeschcke, V, Batterham, P & Hoffmann, A A 2008, ' Nucleotide diversity in the Hsp90 gene in natural populations of Drosophila melanogaster from Australia ', Insect Molecular Biology, vol. 17, no. 6, pp. 685-697 . https://doi.org/10.1111/j.1365-2583.2008.00843.x
Hsp90 is regarded as one of the best candidates for an evolved mechanism that regulates the expression of genetic and phenotypic variability. We examined nucleotide diversity in both the promoter and coding regions of Hsp90, the gene which encodes Hs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646bc1224b819b53a9571dfaed4b88dd
https://doi.org/10.1111/j.1365-2583.2008.00843.x
https://doi.org/10.1111/j.1365-2583.2008.00843.x
Autor:
Marla Tipping, Eefang Yu, Floris Bosveld, Claire C. Milton, Yohanns Bellaïche, Kieran F. Harvey, Liu Yang, Alexey Veraksa, Joffrey L. Degoutin
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
Nature Cell Biology, Nature Publishing Group, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
Nature Cell Biology, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
Nature Cell Biology, Nature Publishing Group, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
International audience; The atypical cadherins Fat (Ft) and Dachsous (Ds) control tissue growth through the Salvador–Warts–Hippo (SWH) pathway, and also regulate planar cell polarity and morphogenesis. Ft and Ds engage in reciprocal signalling as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d23b57320b0ce49230d37437614d17
Publikováno v:
Cell death and differentiation. 18(8)
The Salvador–Warts–Hippo (SWH) pathway is a key controller of tissue growth in both flies and mammals, and deregulation of pathway activity contributes to tumour formation. The SWH pathway regulates cell growth, proliferation and apoptosis by res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76418ba923687683e476aa41da933404
https://pubmed.ncbi.nlm.nih.gov/21311569
https://pubmed.ncbi.nlm.nih.gov/21311569
Publikováno v:
Development (Cambridge, England). 137(5)
The Salvador-Warts-Hippo (SWH) pathway contains multiple growth-inhibitory proteins that control organ size during development by limiting activity of the Yorkie oncoprotein. Increasing evidence indicates that these growth inhibitors act in a complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3dc7aee92d687ea36ed3402aa83dcb
https://pubmed.ncbi.nlm.nih.gov/20110315
https://pubmed.ncbi.nlm.nih.gov/20110315