Estrogen Defines the Dorsal-Ventral Limit of VEGF Regulation to Specify the Location of the Hemogenic Endothelial Niche

Autor: Michael C Dovey, Mauricio Cortes, Kelli J. Carroll, Gregory M. Frechette, Virginie Esain, Sahar Nissim, Trista E. North, Maija K. Garnaas, Nathan D. Lawson, Wolfram Goessling, Wanda Kwan, James M. Harris, Sarah Y. Liu, Marnie E. Halpern, Daniel A. Gorelick, Claire C. Cutting

Publikováno v: Developmental Cell. 29:437-453

The genetic control of hematopoietic stem and progenitor cell (HSPC) function is increasingly understood, however less is known about the interactions specifying the embryonic hematopoietic niche. Here, we report 17β-estradiol (E2) influences the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2185620d9bb2d5fe4120e492af6e9076
https://doi.org/10.1016/j.devcel.2014.04.012

Bilateral Consequences of Chronic Unilateral Deafferentation in the Auditory System of the Cricket Gryllus bimaculatus

Autor: Rohit B. Sangal, Hadley Wilson Horch, Claire R. Williams, Dana M. Riker, Claire C. Cutting, Elizabeth Sheldon, Hannah Peckler

Publikováno v: Developmental Neuroscience. 33:21-37

The auditory system of the cricket has the unusual ability to respond to deafferentation by compensatory growth and synapse formation. Auditory interneurons such as ascending neuron 2 (AN-2) in the cricket Gryllus bimaculatus possess a dendritic arbo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfaff79b96503bedab022fa29a675f72
https://doi.org/10.1159/000322887

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

Autor: James M. Harris, Pulin Li, Elaine Dzierzak, Craig J. Ceol, Trista E. North, Paul L. Huang, Leonard I. Zon, Gerhard J. Weber, Allegra M. Lord, Wolfram Goessling, Marian Peeters, Claire C. Cutting

Publikováno v: North, T E, Goessling, W, Peeters, M, Li, P, Ceol, C, Lord, A M, Weber, G J, Harris, J, Cutting, C C, Huang, P, Dzierzak, E & Zon, L I 2009, ' Hematopoietic Stem Cell Development Is Dependent on Blood Flow ', Cell, vol. 137, no. 4, pp. 736-748 . https://doi.org/10.1016/j.cell.2009.04.023
Cell, 137(4), 736-748. Cell Press

During vertebrate embryogenesis, hematopoietic stem cells (HSC) arise in the aorta-gonads-mesonephros (AGM) region. A zebrafish chemical genetic screen identified compounds that regulate blood flow as modulators of HSC formation. silent heart (sih) e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b30d5d25f6888403bafcd1e60360a2
https://hdl.handle.net/20.500.11820/4bd3548a-5f32-4db8-bb24-4d9d81768b82

17beta-estradiol has a biphasic effect on the formation of hematopoietic stem cells

Autor: Trista E. North, Michael C Dovey, Daniel Gorelick, Sahar Nissim, Maija K. Garnaas, Wanda Kwan, James M. Harris, Gregory M. Frechette, Virginie Esain, Wolfram Goessling, Kelli J. Carroll, Marnie Halpern, Claire C. Cutting

Publikováno v: Experimental Hematology. 41:S12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::530ee5f548b70eb48c9ae53001383bfc
https://doi.org/10.1016/j.exphem.2013.05.046

Metabolism-Induced Reactive Oxygen Species and Hif1α-Mediated Gene Regulation Control the Timing and Magnitude of Hematopoietic Stem Cell Induction

Autor: Michael C Dovey, Maija K. Garnaas, Andrew G. Cox, Gregory M. Frechette, Claire C. Cutting, Matthew G. Vander Heiden, Lauren J. Harris, James M. Harris, Trista E. North, Barry H. Paw, Mauricio Cortes, Wolfram Goessling

Publikováno v: Blood. 118:1266-1266

Abstract 1266 During development, the embryo is exposed to rapidly changing metabolic conditions and demands. The impact of elevated glucose levels on the developing hematopoietic system is not well characterized. Intriguingly, children born to mothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a49d0d947053aaffbba8f212b397a6e0
https://doi.org/10.1182/blood.v118.21.1266.1266