Back pain exercise therapy remodels human epigenetic profiles in buccal and human peripheral blood mononuclear cells: an exploratory study in young male participants

Autor: Claire Burny, Mia Potočnjak, Annika Hestermann, Sophie Gartemann, Michael Hollmann, Frank Schifferdecker-Hoch, Nina Markanovic, Simone Di Sanzo, Michael Günsel, Victor Solis-Mezarino, Moritz Voelker-Albert

Publikováno v: Frontiers in Sports and Active Living, Vol 6 (2024)

BackgroundWith its high and increasing lifetime prevalence, back pain represents a contemporary challenge for patients and healthcare providers. Monitored exercise therapy is a commonly prescribed treatment to relieve pain and functional limitations.

Externí odkaz: https://doaj.org/article/8e5db8d2356d47e0a43ada3d76fdeb4d

Early diagnosis of gestational trophoblastic neoplasia based on trajectory classification with compartment modeling

Autor: Claire Burny, Muriel Rabilloud, François Golfier, Jérôme Massardier, Touria Hajri, Anne-Marie Schott, Fabien Subtil

Publikováno v: BMC Medical Research Methodology, Vol 16, Iss 1, Pp 1-10 (2016)

Abstract Background In randomized clinical trials or observational studies, it is common to collect biomarker values longitudinally on a cohort of individuals. The investigators may be interested in grouping individuals that share similar changes of

Externí odkaz: https://doaj.org/article/6357e707e66e43d28b7a9c4fae1d49b9

Exploiting Single-Cell Quantitative Data to Map Genetic Variants Having Probabilistic Effects.

Autor: Florent Chuffart, Magali Richard, Daniel Jost, Claire Burny, Hélène Duplus-Bottin, Yoshikazu Ohya, Gaël Yvert

Publikováno v: PLoS Genetics, Vol 12, Iss 8, p e1006213 (2016)

Despite the recent progress in sequencing technologies, genome-wide association studies (GWAS) remain limited by a statistical-power issue: many polymorphisms contribute little to common trait variation and therefore escape detection. The small contr

Externí odkaz: https://doaj.org/article/45d4ad7655d9498db0772f030e9431b1

Single-particle tracking photoactivated localization microscopy of membrane proteins in living plant tissues

Autor: Alexandre Martinière, Yvon Jaillais, Matthieu Pierre Platre, Marcelo Nollmann, Claire Burny, Vincent Bayle, Jean-Bernard Fiche

Publikováno v: Nature Protocols
Nature Protocols, Nature Publishing Group, 2021, 16 (3), pp.1600-1628. ⟨10.1038/s41596-020-00471-4⟩
Nature Protocols, 2021, 16 (3), pp.1600-1628. ⟨10.1038/s41596-020-00471-4⟩

Super-resolution microscopy techniques have pushed the limit of optical imaging to unprecedented spatial resolutions. However, one of the frontiers in nanoscopy is its application to intact living organisms. Here we describe the implementation and ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607193d9da2681aa5a7449ec8a518ca9
https://doi.org/10.1038/s41596-020-00471-4

Cell-to-cell expression dispersion of B-cell surface proteins is linked to genetic variants in humans

Autor: Orsolya Symmons, Gérard Triqueneaux, Claire Burny, Stéphane Janczarski, Henri Gruffat, Gaël Yvert

Publikováno v: Communications Biology
Communications Biology, 2020, 3, ⟨10.1038/s42003-020-1075-1⟩
Communications Biology, Nature Publishing Group, 2020, 3, ⟨10.1038/s42003-020-1075-1⟩
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)

Variability in gene expression across a population of homogeneous cells is known to influence various biological processes. In model organisms, natural genetic variants were found that modify expression dispersion (variability at a fixed mean) but ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49f082353e146c09c2709d713feb8e5
https://hal.science/hal-03040848