Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Claire Breslin"'
Autor:
Claire Breslin, Zhihong Zeng, Victoria Coulthard, Anastasia Zlatanou, Stuart L. Rulten, Keith W. Caldecott
Publikováno v:
DNA repair. 58
Acylpeptide hydrolase (APEH) deacetylates N-alpha-acetylated peptides and selectively degrades oxidised proteins, but the biochemical pathways that are regulated by this protease are unknown. Here, we identify APEH as a component of the cellular resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e341e66edcc8cfe2d4d9ee322b367fb9
https://pubmed.ncbi.nlm.nih.gov/28866241
https://pubmed.ncbi.nlm.nih.gov/28866241
Autor:
Keith W. Caldecott, Claire Breslin
Publikováno v:
Molecular and cellular biology. 29(17)
Oxidative stress is a major source of chromosome single-strand breaks (SSBs), and the repair of these lesions is retarded in neurodegenerative disease. The rate of the repair of oxidative SSBs is accelerated by XRCC1, a scaffold protein that is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b4d12f8f56e8aae1e9d410875e195f
https://pubmed.ncbi.nlm.nih.gov/19546231
https://pubmed.ncbi.nlm.nih.gov/19546231
Autor:
Claire, Breslin, Paula M, Clements, Sherif F, El-Khamisy, Eva, Petermann, Natasha, Iles, Keith W, Caldecott
Publikováno v:
Methods in enzymology. 409
Chromosomal single-strand breaks (SSBs) are the most common lesions arising in cells, but are normally rapidly repaired by multiprotein complexes centered around the scaffold protein, XRCC1. Here, we describe protocols to measure chromosomal SSBs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc904595b2a343a9fe43b0bd4a46fed1
https://pubmed.ncbi.nlm.nih.gov/16793415
https://pubmed.ncbi.nlm.nih.gov/16793415
Autor:
Paula M. Clements, Eva Petermann, Natasha Iles, Keith W. Caldecott, Claire Breslin, Sherif F. El-Khamisy
Chromosomal single-strand breaks (SSBs) are the most common lesions arising in cells, but are normally rapidly repaired by multiprotein complexes centered around the scaffold protein, XRCC1. Here, we describe protocols to measure chromosomal SSBs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e47890428f85b0dfcb87e2c3d0a3f645
https://doi.org/10.1016/s0076-6879(05)09024-5
https://doi.org/10.1016/s0076-6879(05)09024-5
Autor:
Claire Breslin, Sarah L. Allinson, Keith W. Caldecott, Jason L. Parsons, Grigory L. Dianov, Kate M. Sleeth, Irina I. Dianova
Publikováno v:
Nucleic acids research. 32(8)
X-ray repair cross-complementing protein-1 (XRCC1)-deficient cells are sensitive to DNA damaging agents and have delayed processing of DNA base lesions. In support of its role in base excision repair, it was found that XRCC1 forms a tight complex wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a460afd90336fb67f1927f003a7c9230
http://ora.ox.ac.uk/objects/uuid:394e6a05-d49c-4c7f-b034-af8eeb9665a8
http://ora.ox.ac.uk/objects/uuid:394e6a05-d49c-4c7f-b034-af8eeb9665a8
Autor:
Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L., Hanzlikova, Hana, Oliver, Antony W., Caldecott, Keith W.
Publikováno v:
Nucleic Acids Research; 8/18/2015, Vol. 43 Issue 14, p6934-6944, 11p
Autor:
Breslin, Claire, Clements, Paula M., El-Khamisy, Sherif F., Petermann, Eva, Iles, Natasha, Caldecott, Keith W.
Publikováno v:
Methods in Enzymology; 2006, Vol. 409, p24-24, 1p