Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Claire B. Cummins"'
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 42, Iss , Pp 54-57 (2019)
Long-gap rectal atresia, as defined by a distance greater than 3 cm, is an uncommon type of a rare anorectal malformation (ARM). . We report the successful completion of a 3-stage procedure including colostomy and mucous fistula creation, laparoscopi
Externí odkaz:
https://doaj.org/article/94980c81a65a4472a371bd20dc225c53
Autor:
Claire B. Cummins, Kanika Bowen-Jallow, Sadia Tasnim, John Prochaska, Daniel Jupiter, Alex Wright, Byron D. Hughes, Omar Nunez-Lopez, Elizabeth Lyons, Andrea Glaser, Ravi S. Radhakrishnan, Debbe Thompson, Oscar E. Suman
Publikováno v:
Journal of Obesity, Vol 2020 (2020)
Successful lifestyle changes for weight reduction are heavily dependent on recognizing the importance of societal and cultural factors. Patients 13–19 years of age with a BMI ≥95th percentile are eligible for our multidisciplinary adolescent weig
Externí odkaz:
https://doaj.org/article/509b1731b02546d28334311717a91559
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 566 (2020)
Burn-induced cardiac dysfunction is thought to involve mitochondrial dysfunction, although the mechanisms responsible are unclear. In this study, we used our established model of in vivo burn injury to understand the genetic evidence of burn-induced
Externí odkaz:
https://doaj.org/article/d8f215dcf245417b8809235875b1ff10
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2350 (2020)
Burn-induced heart dysfunction is a key factor for patient mortality. However, the molecular mechanisms are not yet fully elucidated. This study sought to understand whether burn-induced heart dysfunction is associated with cardiac mitochondrial dysf
Externí odkaz:
https://doaj.org/article/3dc3383f1141400f849b11f80bd473b3
Autor:
Claire B. Cummins, Xiaofu Wang, Omar Nunez Lopez, Gabriel Graham, Hong-Yan Tie, Jia Zhou, Ravi S. Radhakrishnan
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1567 (2018)
Hepatic stellate cell (HSC) activation is responsible for hepatic fibrogenesis and is associated with an overexpression of transcription 3 (STAT3). Luteolin, a common dietary flavonoid with potent anti-inflammatory properties, has previously demonstr
Externí odkaz:
https://doaj.org/article/b54b54354c214cb7a86cfef601ac0566
Autor:
Rui-Min D. Mao, Taylor P. Williams, Anthony Price, Kayla M. Colvill, Claire B. Cummins, Ravi S. Radhakrishnan
Publikováno v:
Journal of Surgical Research. 283:817-823
Autor:
Jake J Wen, Keyan Mobli, Victoria G Rontoyanni, Claire B Cummins, Geetha L Radhakrishnan, Andrew Murton, Ravi S Radhakrishnan
Publikováno v:
J Am Coll Surg
BACKGROUND: Our previous studies have found that burn injury induces cardiac dysfunction through interruption of the antioxidant-response-element (ARE) pathway in cardiac mitochondria. Nuclear factor erythroid 2–related factor 2 (Nrf2) is a key reg
Autor:
Omar Nunez Lopez, Ravi S. Radhakrishnan, Yanping Gu, Xiaofu Wang, Divya Ramdas, Claire B. Cummins, Christian Sommerhalder, Jia Zhou
Publikováno v:
J Surg Res
Background Hepatic fibrosis is wound-healing response that is the result of hepatic stellate cell (HSC) activation and subsequent excess extracellular matrix deposition. HSCs can be activated by a variety of inflammatory stimuli as well as through th
Autor:
Min, Zhu, Elizabeth E, Blears, Claire B, Cummins, Jordan, Wolf, Omar A, Nunez Lopez, Fredrick J, Bohanon, George C, Kramer, Ravi S, Radhakrishnan
Publikováno v:
Cureus.
In patients with multi-organ system trauma, the diagnosis of coinciding traumatic brain injury can be difficult due to injuries from the hemorrhagic shock that confound clinical and radiographic signs of traumatic brain injury. In this study, a novel
Autor:
Geetha L. Radhakrishnan, Kayla M. Colvill, Jake J. Wen, Taylor P. Williams, Claire B. Cummins, Ravi S. Radhakrishnan
Publikováno v:
Journal of the American College of Surgeons. 232:642-655
Background Imbalance of oxidants/antioxidants results in heart failure, contributing to mortality after burn injury. Cardiac mitochondria are a prime source of reactive oxygen species (ROS), and a mitochondrial-specific antioxidant may improve burn-i