Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claire A. Krasinski"'
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13275-13282 (2018)
Externí odkaz:
https://doaj.org/article/6265c891d84e4abfa1539af4786b0543
Autor:
Qiuchen Zheng, Micheal T. Kebede, Bethany Lee, Claire A. Krasinski, Saadman Islam, Liliana A. Wurfl, Merc M. Kemeh, Valerie A. Ivancic, Charles E. Jakobsche, Donald E. Spratt, Noel D. Lazo
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1342 (2021)
The insulin-degrading enzyme (IDE) possesses a strong ability to degrade insulin and Aβ42 that has been linked to the neurodegeneration in Alzheimer’s disease (AD). Given this, an attractive IDE-centric strategy for the development of therapeutics
Externí odkaz:
https://doaj.org/article/a25d395273c14b41b4557b7a706bbf1a
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13275-13282 (2018)
ACS Omega
ACS Omega
Alzheimer's disease (AD), the most common cause of dementia in the elderly, is the sixth leading cause of death in the United States. We hypothesize that the impaired clearance of Aβ42 from the brain is partly responsible for the onset of sporadic A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4589aa2ad17cff46e041233e58f1d45
https://doaj.org/article/6265c891d84e4abfa1539af4786b0543
https://doaj.org/article/6265c891d84e4abfa1539af4786b0543
Autor:
Noel D. Lazo, Charles E. Jakobsche, Qiuchen Zheng, Donald E. Spratt, Claire A. Krasinski, Bethany Lee, Saadman Islam, Merc M. Kemeh, Micheal T. Kebede, Valerie A. Ivancic, Liliana A. Wurfl
Publikováno v:
Antioxidants
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1342, p 1342 (2021)
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1342, p 1342 (2021)
The insulin-degrading enzyme (IDE) possesses a strong ability to degrade insulin and Aβ42 that has been linked to the neurodegeneration in Alzheimer’s disease (AD). Given this, an attractive IDE-centric strategy for the development of therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b082da8e562ca9e15dd2661e1acfa7e
https://doi.org/10.3390/antiox10091342
https://doi.org/10.3390/antiox10091342
Autor:
Firas F. Awwadi, Benjamin L. Solomon, Christopher P. Landee, Jan L. Wikaira, Claire A. Krasinski, Mark M. Turnbull
Publikováno v:
Journal of Coordination Chemistry. 70:914-935
Reaction of 4-amino-2-fluoropyridine (2-F-4-AP) with copper halides produced the neutral coordination complexes: (2-F-4-AP)2CuX2 (X = Cl(1), Br(2)). 1 crystallizes in the orthorhombic space group Pccn in a distorted square planar geometry. Magnetic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4007c7eebdd374cd6f98f0d00bcce9dd
https://doi.org/10.1080/00958972.2016.1278213
https://doi.org/10.1080/00958972.2016.1278213
Autor:
Claire A. Krasinski, Valerie A. Ivancic, Rebecca J. Meservier, Qiuchen Zheng, Donald E. Spratt, Noel D. Lazo
Publikováno v:
Bioscience Reports
Despite the enormous number of therapeutic advances in medicine, nowadays many diseases are still incurable, mainly due to the lack of knowledge of the pathological biochemical pathways triggering those diseases. For this reason, it is compulsory for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282e99f08fe7a7d4e8b0e194a8e73ad7
https://pubmed.ncbi.nlm.nih.gov/30401732
https://pubmed.ncbi.nlm.nih.gov/30401732
Alzheimer's disease (AD) is the most common neurodegenerative disease resulting in dementia. It is characterized pathologically by extracellular amyloid plaques composed mainly of deposited Aβ42 and intracellular neurofibrillary tangles formed by hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d49e32dd326df21b0c568cb5278e98
https://europepmc.org/articles/PMC7074877/
https://europepmc.org/articles/PMC7074877/
