Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Claire A de March"'
Autor:
Shani Agron, Claire A de March, Reut Weissgross, Eva Mishor, Lior Gorodisky, Tali Weiss, Edna Furman-Haran, Hiroaki Matsunami, Noam Sobel
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002442 (2023)
Rodent tears contain social chemosignals with diverse effects, including blocking male aggression. Human tears also contain a chemosignal that lowers male testosterone, but its behavioral significance was unclear. Because reduced testosterone is asso
Externí odkaz:
https://doaj.org/article/409a049214194ebabbc474d1742baa3e
Autor:
Kevin W. Zhu, Shawn D. Burton, Maira H. Nagai, Justin D. Silverman, Claire A. de March, Matt Wachowiak, Hiroaki Matsunami
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Targeted spatial transcriptomics mapped olfactory receptor mRNAs to sections of the murine olfactory bulb to generate an interactive, statistical, 3D model of glomeruli locations and identify an ultra-sensitive receptor-odorant relationship.
Externí odkaz:
https://doaj.org/article/f676caf0b10c40c1968b30c498640846
Autor:
Xiaojing Cong, Wenwen Ren, Jody Pacalon, Rui Xu, Lun Xu, Xuewen Li, Claire A. de March, Hiroaki Matsunami, Hongmeng Yu, Yiqun Yu, Jérôme Golebiowski
Publikováno v:
ACS Central Science, Vol 8, Iss 3, Pp 379-387 (2022)
Externí odkaz:
https://doaj.org/article/2e83968427ce44afbbbf872d3e649224
Autor:
Hitoshi Kida, Yosuke Fukutani, Joel D. Mainland, Claire A. de March, Aashutosh Vihani, Yun Rose Li, Qiuyi Chi, Akemi Toyama, Linda Liu, Masaharu Kameda, Masafumi Yohda, Hiroaki Matsunami
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Biomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sens
Externí odkaz:
https://doaj.org/article/4bb70edca5cc4c01907d20a917e26727
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11546 (2021)
Olfactory receptors (ORs) constitute the largest superfamily of G protein-coupled receptors (GPCRs). ORs are involved in sensing odorants as well as in other ectopic roles in non-nasal tissues. Matching of an enormous number of the olfactory stimulat
Externí odkaz:
https://doaj.org/article/6b3d55e354404b5a8d1d1e509105cf8f
Autor:
Yosuke Fukutani, Masashi Abe, Haruka Saito, Ryo Eguchi, Toshiaki Tazawa, Claire A. de March, Masafumi Yohda, Hiroaki Matsunami
Publikováno v:
Current Biology.
The olfactory system detects a vast number of odorants using hundreds of olfactory receptors (ORs), the largest group of the G protein-coupled receptor (GPCR) superfamily. Each OR is activated by specific odorous ligands. Like other GPCRs, activation
Autor:
Christian B. Billesbølle, Claire A. de March, Wijnand J. C. van der Velden, Ning Ma, Jeevan Tewari, Claudia Llinas del Torrent, Linus Li, Bryan Faust, Nagarajan Vaidehi, Hiroaki Matsunami, Aashish Manglik
Our sense of smell enables us to navigate a vast space of chemically diverse odor molecules. This task is accomplished by the combinatorial activation of approximately 400 olfactory G protein-coupled receptors (GPCRs) encoded in the human genome1–3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b631cd2538099921fc927df0be52bc6
https://doi.org/10.1101/2022.12.20.520951
https://doi.org/10.1101/2022.12.20.520951
Autor:
Rui Xu, Xiaojing Cong, Qian Zheng, Lun Xu, Mengjue J. Ni, Claire A. de March, Hiroaki Matsunami, Jérôme Golebiowski, Minghong Ma, Yiqun Yu
Publikováno v:
FASEB J
Odorant receptors (ORs) expressed in mammalian olfactory sensory neurons are essential for the sense of smell. However, structure-function studies of many ORs are hampered by unsuccessful heterologous expression. To understand and eventually overcome
Publikováno v:
iScience. 26:105908
Autor:
Aashutosh Vihani, Maira H. Nagai, Conan Juan, Claire A. de March, Xiaoyang S. Hu, John Pearson, Hiroaki Matsunami
Identified ligands for > 500 mouse ORsORs are specifically tuned towards individual odorants and their molecular propertiesOdor molecular properties are informative of odor responsesPredictive modeling and convergent evolution analyses suggest specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::974b33a51b30c42d0d975c56ac5b150f
https://doi.org/10.1101/2021.12.27.474279
https://doi.org/10.1101/2021.12.27.474279