Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Claire A Richardson"'
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e13347 (2011)
BackgroundSuccessful observation of behaviour depends upon knowing both which behaviours to look for and focusing on the appropriate areas of the body to observe them. Behaviour based scoring systems have become increasingly widely used to assess ani
Externí odkaz:
https://doaj.org/article/0d6e22e2926d4de48cfc59affe84467f
Autor:
Christopher S. Morrow, Darcie L. Moore, Chung-Yang Yeh, Korbyn Dahlquist, Matthew J. Yousefzadeh, John M. Denu, Michaela E Murphy, Chathurika Henpita, Tadataka Tsuji, Reji Babygirija, Josef P. Clark, Yagna P. R. Jarajapu, Timothy W. Rhoads, Alexis Adrian, Heidi H. Pak, Claire E Richardson, Mariah Calubag, Cara L Green, Cristal M. Hill, Rong Yuan, Ankur Kumar, Michelle Sonsalla, Kishore Chittimalli, Christina D. Camell, Vinal Menon, Mark Bouska, Heather A. Simmons, Yun Zhu, Kyoo-A Lee, Dudley W. Lamming, Eric R McGregor, Hua Bai, Judith Simcox, Carolina Soto-Palma, Akilavalli Narasimhan
Publikováno v:
GeroScience
Autor:
Claudine E. Bayles, Danielle E. Hale, Ali Konieczny, Veronica D. Anderson, Claire R. Richardson, Katelyn V. Brown, Jennifer T. Nguyen, Jacob Hecht, Nora Schwartz, Madan K. Kharel, Felix Amissah, Thomas C. Dowling, S. Eric Nybo
Publikováno v:
Toxicology and applied pharmacology.
The anthracyclines are a family of natural products isolated from soil bacteria with over 2000 chemical representatives. Since their discovery seventy years ago by Waksman and co-workers, anthracyclines have become one of the best-characterized antic
Autor:
Douglas J Cattie, Claire E Richardson, Kirthi C Reddy, Elan M Ness-Cohn, Rita Droste, Mary K Thompson, Wendy V Gilbert, Dennis H Kim
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006326 (2016)
The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the assembly of the 43S pre-initiation complex in eukaryotes. Prior studies have demonstrated that not all subunits of eIF3 are essential for the initiation of
Externí odkaz:
https://doaj.org/article/945edc35e80548d9a13d3b939a1dbfdf
Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals
Autor:
Charu Ramakrishnan, Yoon Seok Kim, Lydia-Marie Joubert, Karl Deisseroth, Kang Shen, Ariane Tom, Jeffrey B.-H. Tok, Huiliang Wang, Yuanwen Jiang, Shucheng Chen, Claire E. Richardson, Xiao Wang, Cheng Wang, Sergiu P. Pașca, Toru Katsumata, Jia Liu, Zhenan Bao, Lief E. Fenno, Fikri Birey
Publikováno v:
Science. 367:1372-1376
From genetics to material to behavior Introducing new genes into an organism can endow new biochemical functions or change the patterns of existing functions, but extending these manipulations to structure at the tissue level is challenging. Combinin
Autor:
Claire E. Richardson, Kang Shen
Publikováno v:
Annual Review of Neuroscience. 42:209-226
How the nervous system is wired has been a central question of neuroscience since the inception of the field, and many of the foundational discoveries and conceptual advances have been made through the study of invertebrate experimental organisms, in
Autor:
Claire E Richardson, Kerri A Spilker, Juan G Cueva, John Perrino, Miriam B Goodman, Kang Shen
Publikováno v:
eLife, Vol 3 (2014)
In neuronal processes, microtubules (MTs) provide structural support and serve as tracks for molecular motors. While it is known that neuronal MTs are more stable than MTs in non-neuronal cells, the molecular mechanisms underlying this stability are
Externí odkaz:
https://doaj.org/article/8173dbddf3214765927b6e981a9f24a8
Autor:
Anna L. M. Smith, Julia C. Whitehall, Carla Bradshaw, David Gay, Fiona Robertson, Alasdair P. Blain, Gavin Hudson, Angela Pyle, David Houghton, Matthew Hunt, James N. Sampson, Craig Stamp, Grace Mallett, Shoba Amarnath, Jack Leslie, Fiona Oakley, Laura Wilson, Angela Baker, Oliver M. Russell, Riem Johnson, Claire A. Richardson, Bhavana Gupta, Iain McCallum, Stuart A. C. McDonald, Seamus Kelly, John C. Mathers, Rakesh Heer, Robert W. Taylor, Neil D. Perkins, Doug M. Turnbull, Owen J. Sansom, Laura C. Greaves
Publikováno v:
Nat Cancer
Oxidative phosphorylation (OXPHOS) defects caused by somatic mitochondrial DNA (mtDNA) mutations increase with age in human colorectal epithelium and are prevalent in colorectal tumours, but whether they actively contribute to tumorigenesis remains u
Autor:
Douglas J. Cattie, Dennis H. Kim, Erik J. Tillman, Gary Ruvkun, Rita Droste, Nicolas J. Lehrbach, Claire E. Richardson, Kirthi C. Reddy
Publikováno v:
Genetics. 210:1329-1337
Animals have evolved critical mechanisms to maintain cellular and organismal proteostasis during development, disease, and exposure to environmental stressors. The Unfolded Protein Response (UPR) is a conserved pathway that senses and responds to the
Autor:
Soo Yeun Lee, Keitaro Yamashita, Charu Ramakrishnan, Keiichi Inoue, Andre Berndt, Karl Deisseroth, Daniel Hilger, William E. Allen, Ron O. Dror, Hideki Kandori, Lief E. Fenno, Claire E. Richardson, Kang Shen, Kathryn E. Evans, Hideaki E. Kato, Joseph M. Paggi, Yoon Seok Kim, Shota Ito, Brian K. Kobilka
Publikováno v:
Nature. 561:349-354
Both designed and natural anion-conducting channelrhodopsins (dACRs and nACRs, respectively) have been widely applied in optogenetics (enabling selective inhibition of target-cell activity during animal behaviour studies), but each class exhibits per