Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Claire A, Chougnet"'
Autor:
Josef Newman, Xiaoying Tong, April Tan, Toni Yeasky, Vanessa Nunes De Paiva, Pietro Presicce, Paranthaman S. Kannan, Kevin Williams, Andreas Damianos, Marione Tamase Newsam, Merline K. Benny, Shu Wu, Karen C. Young, Lisa A. Miller, Suhas G. Kallapur, Claire A. Chougnet, Alan H. Jobe, Roberta Brambilla, Augusto F. Schmidt
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Preterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism. Preterm birth can lead to cerebellar underdevelopment, but the mechanisms of disrupted cerebellar
Externí odkaz:
https://doaj.org/article/4330d26737704358ad8660367418ee35
Autor:
Pietro Presicce, Cynthia Roland, Paranthaman Senthamaraikannan, Monica Cappelletti, McKensie Hammons, Lisa A. Miller, Alan H. Jobe, Claire A. Chougnet, Emily DeFranco, Suhas G. Kallapur
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIL6 signaling plays an important role in triggering labor and IL6 is an established biomarker of intrauterine infection/inflammation (IUI) driven preterm labor (PTL). The biology of IL6 during IUI at the maternal-fetal interface was inves
Externí odkaz:
https://doaj.org/article/922d9b5b34804f2f99ba4aa1523324fc
Autor:
Pietro Presicce, Monica Cappelletti, Marco Morselli, Feiyang Ma, Paranthaman Senthamaraikannan, Giulia Protti, Brian B. Nadel, Laila Aryan, Mansoureh Eghbali, Lukasz Salwinski, Neema Pithia, Emily De Franco, Lisa A. Miller, Matteo Pellegrini, Alan H. Jobe, Claire A. Chougnet, Suhas G. Kallapur
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108118- (2023)
Summary: Intrauterine infection/inflammation (IUI) is a frequent complication of pregnancy leading to preterm labor and fetal inflammation. How inflammation is modulated at the maternal-fetal interface is unresolved. We compared transcriptomics of am
Externí odkaz:
https://doaj.org/article/77d0fd7b7d1341148a8871c73ddb3327
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Age-associated microglial dysfunction contributes to the accumulation of amyloid-β (Aβ) plaques in Alzheimer’s disease. Although several studies have shown age-related declines in the phagocytic capacity of myeloid cells, relatively few
Externí odkaz:
https://doaj.org/article/155b2661eb834da5aff628b3216a5b65
Autor:
Shweta Mahajan, Aria Alexander, Zachary Koenig, Nicholas Saba, Nina Prasanphanich, David A. Hildeman, Claire A. Chougnet, Emily DeFranco, Sandra Andorf, Tamara Tilburgs
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
Maternal decidual CD8+ T cells must integrate the antithetical demands of providing immunity to infection while maintaining immune tolerance for fetal and placental antigens. Human decidual CD8+ T cells were shown to be highly differentiated memory T
Externí odkaz:
https://doaj.org/article/781060653b01409aa72fd46062791775
Autor:
Laura Atehortua, Jamie Morris, Scott E. Street, Nicholas Bedel, W. Sean Davidson, Claire A. Chougnet
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 9, Pp 100425- (2023)
Plasma levels of HDL cholesterol are inversely associated with CVD progression. It is becoming increasingly clear that HDL plays important roles in immunity that go beyond its traditionally understood roles in lipid transport. We previously reported
Externí odkaz:
https://doaj.org/article/7154b2275503415faba88b6eff8b3219
Autor:
Jessica R. Doll, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Jennifer L. Wayland, Adrienne Wilburn, Benjamin Weinhaus, Claire A. Chougnet, Daniela Giordano, Monica Cappelletti, Pietro Presicce, Suhas G. Kallapur, Nathan Salomonis, Tamara Tilburgs, Senad Divanovic
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112352- (2023)
Summary: Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF pro
Externí odkaz:
https://doaj.org/article/59d828a84fe34ca5847dca21b989426e
Autor:
Laura Atehortua, Mirza Baig, Jamie Morris, Sarah Trentman, W. Sean Davidson, Carl J. Fichtenbaum, Claire A. Chougnet
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cardiovascular disease (CVD) is a leading cause of enhanced morbidity and mortality in persons with HIV (PWH) in the era of highly active antiretroviral therapy (AART). However, the underlying mechanisms are not fully understood. Regulatory T cells (
Externí odkaz:
https://doaj.org/article/4e030e8ea7424e92b4fe05dba8ee0479
Autor:
Augusto F. Schmidt, Daniel J. Schnell, Kenneth P. Eaton, Kashish Chetal, Paranthaman S. Kannan, Lisa A. Miller, Claire A. Chougnet, Daniel T. Swarr, Alan H. Jobe, Nathan Salomonis, Beena D. Kamath-Rayne
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Accurate estimate of fetal maturity could provide individualized guidance for delivery of complicated pregnancies. However, current methods are invasive, have low accuracy, and are limited to fetal lung maturation. To identify diagnostic gestational
Externí odkaz:
https://doaj.org/article/65f498c27850421f9199b07071f4e9d3
Autor:
Imke Lingel, Adrienne N. Wilburn, Julie Hargis, Jaclyn W. McAlees, Yves Laumonnier, Claire A. Chougnet, Hitesh Deshmukh, Peter König, Ian P. Lewkowich, Inken Schmudde
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Changes in microbiome (dysbiosis) contribute to severity of allergic asthma. Preexisting epidemiological studies in humans correlate perinatal dysbiosis with increased long-term asthma severity. However, these studies cannot discriminate between pren
Externí odkaz:
https://doaj.org/article/25369152ac0f4e88961f12728fc0e182