Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Claire Adcock"'
Autor:
Jodie Manini, Claire Adcock, Alfred Schmidt, Zarin Brown, Robin Alec Fairhurst, Rachael Profit, John Reilly, David C. Budd, Caroline Wilson, Simon J. Watson, Brian Cox, Kamlesh Bala, Jennifer Willis, Lucy Barker, Markus Furegati, David Andrew Sandham, Katharine L. Turner, Rowan Stringer, Catherine Leblanc, Gareth Williams, Gerald Dubois
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(16)
High throughput screening identified a 7-azaindole-3-acetic acid scaffold as a novel CRTh2 receptor antagonist chemotype, which could be optimised to furnish a highly selective compound with good functional potency for inhibition of human eosinophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662232891c4a20f4a3460f90d84eb7a6
https://pubmed.ncbi.nlm.nih.gov/19592244
https://pubmed.ncbi.nlm.nih.gov/19592244
Autor:
Claire Adcock, Francisco Cuenca Alonso, Niall M. B. Martin, Chris Mydlowski, Kristel Blackburn, Keith Allan Menear, Louise Copsey, Armelle Le Gall, Sylvie Gomez, Graeme C. M. Smith, Carlos Fenandez Lence, Hashim Javaid, Jan Drzewiecki, Alexandra Fundo
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(14)
We have previously described poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors based on a substituted benzyl-phthalazinone scaffold. As an alternative chemical template, a novel series of alkoxybenzamides were developed with restricted conformation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0764f908b9acc17224a50fba6d1f26aa
https://pubmed.ncbi.nlm.nih.gov/18579376
https://pubmed.ncbi.nlm.nih.gov/18579376
Autor:
Keith A. Menear, Niall M. B. Martin, Claire Adcock, Robert Boulter, Xiao-ling Cockcroft, Louise Copsey, Aaron Cranston, Krystyna J. Dillon, Jan Drzewiecki, Sheila Garman, Sylvie Gomez, Hashim Javaid, Frank Kerrigan, Charlotte Knights, Alan Lau, Vincent M. Loh Jr., Ian T. W. Matthews, Stephen Moore, Mark J. O’Connor, Graeme C. M. Smith
Publikováno v:
Journal of Medicinal Chemistry; Oct2008, Vol. 51 Issue 20, p6581-6591, 11p