Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Claire, Lugnier"'
Autor:
Issaka Yougbare, Lazare Belemnaba, Caroline Morin, Abdurazzag Abusnina, Yannick F. Senouvo, Thérèse Keravis, Claire Lugnier, Eric Rousseau
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Chronic inflammation is a deleterious process occurring in several pulmonary diseases; it is a driving force promoting tumorigenesis. By regulating local cyclic nucleotide concentration, cyclic nucleotide phosphodiesterases (PDE) govern important bio
Externí odkaz:
https://doaj.org/article/be32e35985f94f708ffd62d2265d55c3
Publikováno v:
CURRENT MEDICAL AND DRUG RESEARCH. 5:1-4
Primary infection of SARS-CoV-2 (novel coronavirus or 2019-nCoV), which leads to Covid-19, targets specific cells, such as nasal, bronchial epithelial and pneumocytes, through the viral structural spike (S) protein that binds to the angiotensin-conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d0720954d34cecd7a900697a65bae0a
https://doi.org/10.53517/cmdr.2581-5008.512021212
https://doi.org/10.53517/cmdr.2581-5008.512021212
Autor:
Liliane Tetsi, Anne-Laure Charles, Isabelle Georg, Fabienne Goupilleau, Anne Lejay, Samy Talha, Myriam Maumy-Bertrand, Claire Lugnier, Bernard Geny
Publikováno v:
Antioxidants, Vol 8, Iss 4, p 93 (2019)
Lower-limb ischemia-reperfusion (IR) is frequent and associated with significant morbidity and mortality. Phosphodiesterase 5 inhibitors demonstrated antioxidant and beneficial effects in several organs submitted to IR, but their effects on muscle mi
Externí odkaz:
https://doaj.org/article/38c276bc612f43d5b48c25b2636a7993
Publikováno v:
Neurology India. 69(6)
Acute ischemic stroke (AIS) leads to neuronal and endothelial damage that activate the release of proinflammatory mediators such as lipoprotein-associated phospholipase A2 (Lp-PLA2), which lead to the development of brain edema injury. Most of statin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2eba69f93f625009bd577039b40d5b
https://pubmed.ncbi.nlm.nih.gov/34979662
https://pubmed.ncbi.nlm.nih.gov/34979662
Autor:
Thérèse Keravis, Laure Favot, Abdurrazag A Abusnina, Anita Anton, Hélène Justiniano, Raffaella Soleti, Eid Alabed Alibrahim, Gilles Simard, Ramaroson Andriantsitohaina, Claire Lugnier
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145291 (2015)
The vasculoprotective properties of delphinidin are driven mainly by its action on endothelial cells. Moreover, delphinidin displays anti-angiogenic properties in both in vitro and in vivo angiogenesis models and thereby might prevent the development
Externí odkaz:
https://doaj.org/article/31573f5bff4247d3aaa948544bb61c40
Autor:
Claire Lugnier
Publikováno v:
International Journal of Molecular Sciences. 23:10616
Cyclic nucleotides (cAMP, cGMP) play a major role in normal and pathologic signaling. Beyond receptors, cyclic nucleotide phosphodiesterases; (PDEs) rapidly convert the cyclic nucleotide in its respective 5′-nucleotide to control intracellular cAMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec44e66877488104900526d138b8088
https://doi.org/10.3390/ijms231810616
https://doi.org/10.3390/ijms231810616
Publikováno v:
Biochemical Pharmacology
Graphical abstract
Angiotensin-converting enzyme 2 (ACE2) is the binding-site and entry-point for SARS-CoV-2 in human and highly expressed in the lung. Cigarette smoking (CS) is the leading cause of pulmonary and cardiovascular diseases. Chronic
Angiotensin-converting enzyme 2 (ACE2) is the binding-site and entry-point for SARS-CoV-2 in human and highly expressed in the lung. Cigarette smoking (CS) is the leading cause of pulmonary and cardiovascular diseases. Chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3c13b56275d59a15e5635c0f0e2339
https://pubmed.ncbi.nlm.nih.gov/33515531
https://pubmed.ncbi.nlm.nih.gov/33515531
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1867(3)
Nephritis remains the most common severe manifestation of systemic lupus erythematosus in which auto-antibodies mediate chronic inflammation and kidney damage. cAMP-phosphodiesterases regulate sodium excretion and inflammation in various tissues. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8664088e22a5009c028ec5ed8d92d9
https://pubmed.ncbi.nlm.nih.gov/33227426
https://pubmed.ncbi.nlm.nih.gov/33227426
Autor:
Claire Lugnier, Jacques Marescaux, Mahdi Al-Taher, Manuel Barberio, Bernard Geny, Michele Diana, Anne-Laure Charles, Isabelle Georg, Anne Lejay, Eric Felli, Liliane Tetsi
Publikováno v:
Journal of laparoendoscopicadvanced surgical techniques. Part A. 30(9)
Background: Peripheral arterial disease has high incidence and complication rates. Vessel recanalization represents the main therapy. However, it induces reperfusion injury. Preconditioning with si...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec8832084e87a454889c2aeb1e46211
https://pubmed.ncbi.nlm.nih.gov/32609046
https://pubmed.ncbi.nlm.nih.gov/32609046
Autor:
Thérèse Keravis, Fanny Monneaux, Issaka Yougbaré, Lucien Gazi, Jean-Jacques Bourguignon, Sylviane Muller, Claire Lugnier
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28899 (2012)
Systemic lupus erythematosus is a polymorphic and multigenic inflammatory autoimmune disease. Cyclic AMP (cAMP) modulates inflammation and the inhibition of cyclic nucleotide phosphodiesterase type 4 (PDE4), which specifically hydrolyzes cAMP, inhibi
Externí odkaz:
https://doaj.org/article/cd16cca26c214f7b93108859ca266b0a