Impact of Aspirin and Clopidogrel Hyporesponsiveness in Patients Treated With Drug-Eluting Stents

Autor: Peter L. Duffy, Thomas Stuckey, Adapt-Des Investigators, Franz-Josef Neumann, Giora Weisz, Roxana Mehran, Claire Litherland, Ori Ben-Yehuda, D. Christopher Metzger, Gregg W. Stone, Michael Rinaldi, Ernest L. Mazzaferri, Paul A. Gurbel, Timothy D. Henry, Bernhard Witzenbichler, Bruce R. Brodie, Charles A. Simonton, David A. Cox, Philippe Généreux, Ajay J. Kirtane

Publikováno v: JACC: Cardiovascular Interventions. 10:1607-1617

Objectives In this analysis of 2-year outcomes in the ADAPT-DES (Assessment of Dual AntiPlatelet Therapy with Drug-Eluting Stents) study, the authors sought to examine the independent associations between platelet reactivity to both aspirin and clopi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df00e19df9b051c4ed0f4790fa2ba485
https://doi.org/10.1016/j.jcin.2017.05.059

Relation Between Platelet Count and Platelet Reactivity to Thrombotic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study

Autor: Christopher Metzger, Gennaro Giustino, Peter L. Duffy, Ernest L. Mazzaferri, Ajay J. Kirtane, George Dangas, Giora Weisz, Franz-Josef Neumann, Philippe Généreux, Bruce R. Brodie, Usman Baber, Claire Litherland, Akiko Maehara, Roxana Mehran, Dominic P. Francese, Michael J. Rinaldi, David A. Cox, Gregg W. Stone, Thomas Stuckey, Bernhard Witzenbichler, Timothy D. Henry

Publikováno v: The American Journal of Cardiology. 117:1703-1713

Whether the association between platelet count (PC) and thrombotic and bleeding risk is independent of or varies by residual platelet reactivity to antiplatelet therapies is unclear. We sought to investigate the independent and combined effects of PC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab5fd5076a5cd1e28308a801658aef6
https://doi.org/10.1016/j.amjcard.2016.03.001

Impact of Hemoglobin A1c Levels on Residual Platelet Reactivity and Outcomes After Insertion of Coronary Drug-Eluting Stents (from the ADAPT-DES Study)

Autor: Jennifer Yu, Bernhard Witzenbichler, Timothy D. Henry, Akiko Maehara, Roxana Mehran, D. Christopher Metzger, Peter Clemmensen, Peter L. Duffy, Franz-Josef Neumann, Claire Litherland, Ajay J. Kirtane, Mikkel Malby Schoos, Giora Weisz, David A. Cox, Bruce R. Brodie, Thomas Stuckey, Ernest L. Mazzaferri, Gregg W. Stone, Michael J. Rinaldi, George Dangas

Publikováno v: Schoos, M M, Dangas, G D, Mehran, R, Kirtane, A J, Yu, J, Litherland, C, Clemmensen, P, Stuckey, T D, Witzenbichler, B, Weisz, G, Rinaldi, M J, Neumann, F-J, Metzger, D C, Henry, T D, Cox, D A, Duffy, P L, Brodie, B R, Mazzaferri, E L, Maehara, A & Stone, G W 2016, ' Impact of Hemoglobin A1c Levels on Residual Platelet Reactivity and Outcomes After Insertion of Coronary Drug-Eluting Stents (from the ADAPT-DES Study) ', The American Journal of Cardiology, vol. 117, no. 2, pp. 192-200 . https://doi.org/10.1016/j.amjcard.2015.10.037

An increasing hemoglobin A1c (HbA1c) level portends an adverse cardiovascular prognosis; however, the association between glycemic control, platelet reactivity, and outcomes after percutaneous coronary intervention (PCI) with drug-eluting stents (DES

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5460f516b4cfd69204b1f54ca1850571
https://doi.org/10.1016/j.amjcard.2015.10.037

Incidence, Predictors, and Impact of Post-Discharge Bleeding After Percutaneous Coronary Intervention

Autor: Timothy D. Henry, Michael J. Rinaldi, Tullio Palmerini, Peter L. Duffy, Franz-Josef Neumann, Mayank Yadav, Philippe Généreux, Claire Litherland, Roxana Mehran, Dominic P. Francese, Bernhard Witzenbichler, Gennaro Giustino, Ajay J. Kirtane, Giora Weisz, David A. Cox, Gregg W. Stone, Ernest L. Mazzaferri, Thomas Stuckey, D. Christopher Metzger

Publikováno v: Journal of the American College of Cardiology. 66:1036-1045

BackgroundThe incidence, predictors, and prognostic impact of post-discharge bleeding (PDB) after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation are unclear.ObjectivesThis study sought to characterize the determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328afaea9851240b87cdbac3428777f8
https://doi.org/10.1016/j.jacc.2015.06.1323

Effect of Short Procedural Duration With Bivalirudin on Increased Risk of Acute Stent Thrombosis in Patients With STEMI: A Secondary Analysis of the HORIZONS-AMI Randomized Clinical Trial

Autor: Ajay J. Kirtane, Claire Litherland, Guillermo Ortiz, Roxana Mehran, Robert W. Yeh, George Dangas, Duane S. Pinto, C. Michael Gibson, Gregg W. Stone, Hector Tamez, Efthymios N. Deliargyris

Publikováno v: JAMA cardiology. 2(6)

Bivalirudin has been associated with reduced bleeding and mortality during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI). However, increased rates of acute stent thrombosis (AST) have been noted whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8927e0f8297f5d08a805427c13d21795
https://pubmed.ncbi.nlm.nih.gov/28249084