Characterization of Blood Mucosal-Associated Invariant T Cells in Patients With Axial Spondyloarthritis and of Resident Mucosal-Associated Invariant T Cells From the Axial Entheses of Non-Axial Spondyloarthritis Control Patients

Autor: Nicolas, Rosine, Hannah, Rowe, Surya, Koturan, Hanane, Yahia-Cherbal, Claire, Leloup, Abdulla, Watad, Francis, Berenbaum, Jeremie, Sellam, Maxime, Dougados, Vishukumar, Aimanianda, Richard, Cuthbert, Charlie, Bridgewood, Darren, Newton, Elisabetta, Bianchi, Lars, Rogge, Dennis, McGonagle, Corinne, Miceli-Richard

Publikováno v: Arthritisrheumatology (Hoboken, N.J.)REFERENCES. 74(11)

The importance of interleukin-17A (IL-17A) in the pathogenesis of axial spondyloarthritis (SpA) has been demonstrated by the success of IL-17A blockade. However, the nature of the cell populations that produce this important proinflammatory cytokine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::73a765078e9bb866ddd109a1aec85b83
https://pubmed.ncbi.nlm.nih.gov/35166073

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

Autor: Petar Scepanovic, Julie Hunkapiller, Jacob Bergstedt, Alejandra Urrutia, Jacques Fellay, Lluis Quintana-Murci, Hélène Quach, Friederike Jönsson, Cherie Green, Olivier Lantz, Lars Rogge, Stéphanie Thomas, Vincent Rouilly, Barbara Piasecka, Yoong Wearn Lim, Claire Leloup, Cécile Alanio, Isabelle Peguillet, Christian Hammer, Benoit Beitz, Magnus Fontes, Magge Zepeda, Matthew L. Albert, Valentina Libri, James P. Di Santo, Etienne Patin, Milena Hasan, François Huetz, Darragh Duffy

Publikováno v: Nature Immunology
Nature Immunology, 2018, 19 (3), pp.302-314. ⟨10.1038/s41590-018-0049-7⟩
Nature Immunology, Nature Publishing Group, 2018, 19 (3), pp.302-314. ⟨10.1038/s41590-018-0049-7⟩

A Publisher Correction to this article was published on 03 May 2018; International audience; The quantification and characterization of circulating immune cells provide key indicators of human health and disease. To identify the relative effects of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7632e50a0858023a8e68c6aaad539182
https://hal-pasteur.archives-ouvertes.fr/pasteur-01768943

pDCs efficiently process synthetic long peptides to induce functional virus- and tumour-specific T-cell responses

Autor: Caroline, Aspord, Claire, Leloup, Sabine, Reche, Joel, Plumas

Publikováno v: European journal of immunology. 44(10)

Robust cell-mediated immunity is required for immune control of tumours and protection from viral infections, with both CD4(+) and CD8(+) T cells playing a pivotal role. Synthetic long peptides (SLPs) represent an attractive way to induce such combin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52c832ccabe8eaae8098f627ff4f3684
https://pubmed.ncbi.nlm.nih.gov/25043392

Imiquimod Inhibits Melanoma Development by Promoting pDC Cytotoxic Functions and Impeding Tumor Vascularization

Autor: Caroline Aspord, Julie Charles, Joel Plumas, Marie-Thérèse Leccia, Jean-Paul Molens, Laetitia Tramcourt, Claire Leloup

Publikováno v: Journal of Investigative Dermatology. (10):2551-2561

Imiquimod (IMQ) is a synthetic Toll-like receptor (TLR7/8) ligand that can trigger antiviral and antitumor activities. Despite evidence of potent therapeutic effects, the clinical use of IMQ in melanoma is impeded by incomplete understanding of its m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3149e9c862a51e86e7f47932f8d0bdd