Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Claire, Germain"'
Autor:
Claire Germain, Matthias Peipp, Simon E Plyte, Marie Fraudeau, Dorothee Winterberg, Camille Rousseau, Gaetano Sodaro, Maxime Audin, Alexandre Ivagnes, Hans Heinrich Oberg, Pierre Emmanuel Gerard, Daniela Wesch, Julie Prigent
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/51e22c60338d49c79090d496bc8fc3b4
Autor:
Priyanka Devi-Marulkar, Solène Fastenackels, Pierre Karapentiantz, Jérémy Goc, Claire Germain, Hélène Kaplon, Samantha Knockaert, Daniel Olive, Marylou Panouillot, Pierre Validire, Diane Damotte, Marco Alifano, Juliette Murris, Sandrine Katsahian, Myriam Lawand, Marie-Caroline Dieu-Nosjean
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Regulatory T cells (Tregs) have similar immune profiles in tertiary lymphoid structures of lung cancer and non-TLS areas, with tumor-infiltrating Tregs found to inhibit the proliferation and cytokine secretion of CD4 + conventional T cells.
Externí odkaz:
https://doaj.org/article/6843b8158e4442199fa24d4eee02cf0d
Autor:
Claire Germain, Julie Garibal, Valérie Doppler, Fanny Baran-Marszak, Florence Cymbalista, Julien Caumartin, Pierre Langlade-Demoyen, Maria Wehbe, Thierry Huet
Publikováno v:
Clinical Immunology Communications, Vol 1, Iss , Pp 35-44 (2021)
Human telomerase reverse transcriptase (hTERT) is broadly expressed in many cancers. High hTERT expression have been described in chronic lymphocytic leukemia (CLL). Here we investigated the relationship between anti-hTERT immunity and disease progre
Externí odkaz:
https://doaj.org/article/20171fe6484d48c7bf25ab7d867a845a
Autor:
Veronique M. Braud, Aïda Meghraoui-Kheddar, Roxane Elaldi, Luciana Petti, Claire Germain, Fabienne Anjuère
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The success of immune checkpoint therapy in cancer has changed our way of thinking, promoting the design of future cancer treatments that places the immune system at the center stage. The knowledge gained on immune regulation and tolerance helped the
Externí odkaz:
https://doaj.org/article/98452b81cf9d4475b167e192f440aac4
Autor:
Claire Germain, Priyanka Devi-Marulkar, Samantha Knockaert, Jérôme Biton, Hélène Kaplon, Laïla Letaïef, Jérémy Goc, Agathe Seguin-Givelet, Dominique Gossot, Nicolas Girard, Pierre Validire, Marine Lefèvre, Diane Damotte, Marco Alifano, François M. Lemoine, Keith E. Steele, Jean-Luc Teillaud, Scott A. Hammond, Marie-Caroline Dieu-Nosjean
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The presence of tertiary lymphoid structures (TLS) in the tumor microenvironment is associated with better clinical outcome in many cancers. In non-small cell lung cancer (NSCLC), we have previously showed that a high density of B cells within TLS (T
Externí odkaz:
https://doaj.org/article/757b1a291fa64d989f66f304930a5ace
Autor:
Jules Russick, Pierre-Emmanuel Joubert, Mélanie Gillard-Bocquet, Carine Torset, Maxime Meylan, Florent Petitprez, Marie-Agnes Dragon-Durey, Solenne Marmier, Aditi Varthaman, Nathalie Josseaume, Claire Germain, Pierre Validire, Ludovic Fournel, Audrey Lupo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response. Emerging data rev
Externí odkaz:
https://doaj.org/article/66cfd0aa9b7a4ab3ad675fae3785d405
Autor:
Catherine Sautès-Fridman, Wolf H. Fridman, Xavier Cathelineau, Claire Germain, Sarah Bourass, Benedicte Buttard, Audrey Moatti, Stephane Oudard, Alexandre Ingels, Rafael Sanchez-Salas, Pierre Validire, Laetitia Lacroix, Florent Petitprez, Yann Vano, Etienne Becht, Nicolas A. Giraldo
Purpose: The efficacy of PD-1 checkpoint blockade as adjuvant therapy in localized clear cell renal cell carcinoma (ccRCC) is currently unknown. The identification of tumor microenvironment (TME) prognostic biomarkers in this setting may help define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bfdff03ef6e0cdeacab6c93b421371
https://doi.org/10.1158/1078-0432.c.6526922.v1
https://doi.org/10.1158/1078-0432.c.6526922.v1
Autor:
Diane Damotte, Hélène Blons, Ronald Herbst, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Pierre Laurent-Puig, Claire Germain, Marie Wislez, Jeremy Goc, Karen Leroy, François Goldwasser, Pascaline Boudou-Rouquette, Jennifer Arrondeau, Hanane Ouakrim, Marco Alifano, Nicolas Pécuchet, Audrey Mansuet-Lupo, Jérôme Biton
Purpose: By unlocking antitumor immunity, antibodies targeting programmed cell death 1 (PD-1) exhibit impressive clinical results in non–small cell lung cancer, underlining the strong interactions between tumor and immune cells. However, factors th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be9933892cb63e1e90c325d91851c84
https://doi.org/10.1158/1078-0432.c.6527516
https://doi.org/10.1158/1078-0432.c.6527516
Autor:
Catherine Sautès-Fridman, Wolf H. Fridman, Xavier Cathelineau, Claire Germain, Sarah Bourass, Benedicte Buttard, Audrey Moatti, Stephane Oudard, Alexandre Ingels, Rafael Sanchez-Salas, Pierre Validire, Laetitia Lacroix, Florent Petitprez, Yann Vano, Etienne Becht, Nicolas A. Giraldo
Table S1. Demographic and clinical characteristics of the analyzed patients; Table S2. Antibodies and conditions used for the IHC studies; Table S3. List of immune-related genes analyzed by Low Density Array; Figure S1. Gating and data analysis strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154a9059b10773872b215ef046eb6296
https://doi.org/10.1158/1078-0432.22468394
https://doi.org/10.1158/1078-0432.22468394
Autor:
Diane Damotte, Hélène Blons, Ronald Herbst, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Pierre Laurent-Puig, Claire Germain, Marie Wislez, Jeremy Goc, Karen Leroy, François Goldwasser, Pascaline Boudou-Rouquette, Jennifer Arrondeau, Hanane Ouakrim, Marco Alifano, Nicolas Pécuchet, Audrey Mansuet-Lupo, Jérôme Biton
Figures S1-12 Tables S1-S4 Supplementary material Supplementary Table S1. Antibodies used in flow cytometry experiments. Supplementary Table S2. Baseline characteristics of the 221 patients with lung adenocarcinoma in each TIP. Supplementary Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793e050c7a3a699dad8917392d81e61
https://doi.org/10.1158/1078-0432.22470311
https://doi.org/10.1158/1078-0432.22470311