Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Claire, Bernhard"'
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Akademický článek
Targeted radionuclide therapy against GARP expressing T regulatory cells after tumour priming with external beam radiotherapy in a murine syngeneic model
Autor: Pierre-Simon Bellaye, Alexandre MM. Dias, Jean-Marc Vrigneaud, Alexanne Bouchard, Mathieu Moreau, Camille Petitot, Claire Bernhard, Michael Claron, Lisa Froidurot, Véronique Morgand, Mélanie Guillemin, Marie Monterrat, Céline Mirjolet, Carmen Garrido, Evelyne Kohli, Bertrand Collin
Publikováno v: Heliyon, Vol 10, Iss 20, Pp e39543- (2024)
Purpose: Radiation therapy (RT) exerts its anti-tumour efficacy by inducing direct damage to cancer cells but also through modification of the tumour microenvironment (TME) by inducing immunogenic antitumor response. Conversely, RT also promotes an i
Externí odkaz: https://doaj.org/article/7bec184ffac246c19ba7e43daa2823e0
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3
Akademický článek
A New pH-Dependent Macrocyclic Rhodamine B-Based Fluorescent Probe for Copper Detection in White Wine
Autor: Nour Doumani, Elias Bou-Maroun, Jacqueline Maalouly, Maya Tueni, Adrien Dubois, Claire Bernhard, Franck Denat, Philippe Cayot, Nicolas Sok
Publikováno v: Sensors, Vol 19, Iss 20, p 4514 (2019)
For efficiently measuring copper (II) ions in the acidic media of white wine, a new chemosensor based on rhodamine B coupled to a tetraazamacrocyclic ring (13aneN4CH2NH2) was designed and synthesized by a one-pot reaction using ethanol as a green sol
Externí odkaz: https://doaj.org/article/40b800ac7ebd4cfc8a74a435da218219
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4
Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors
Autor: Pierre Adumeau, René Raavé, Milou Boswinkel, Sandra Heskamp, Hans J. C. T. Wessels, Alain J. van Gool, Mathieu Moreau, Claire Bernhard, Laurène Da Costa, Victor Goncalves, Franck Denat
Publikováno v: Bioconjugate Chemistry, 33, 3, pp. 530-540
Bioconjugate Chemistry, 33, 530-540
Because positron emission tomography (PET) and optical imaging are very complementary, the combination of these two imaging modalities is very enticing in the oncology field. Such bimodal imaging generally relies on imaging agents bearing two differe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b25d8c7efc9cf76f5f26579228e84b
https://pubmed.ncbi.nlm.nih.gov/35230093
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5
The Scope of Application of Macrocyclic Polyamines Beyond Metal Chelation
Autor: Ibai E. Valverde, Claire Bernhard, David Monchaud, Anthony Romieu, Katerina Duskova, Pauline Lejault
Publikováno v: European Journal of Organic Chemistry. 2019:6146-6157
Recent advances in the use of radiometals for both imaging and therapy has spurred on the development of an original chemistry that endows radionuclide-chelating molecular cages with ever sharper physicochemical properties. Macrocyclic polyamines (MP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f9b9c09e5a945774b0575b2678324f1
https://doi.org/10.1002/ejoc.201900870
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6
Abstract 1401: Lead optimization of radiopharmaceuticals for molecular radiotherapy and preclinical evaluation
Autor: Emma Renard, Olivier Raguin, Victor Goncalves, Celine Mothes, Mathieu Moreau, Claire Bernhard, Peggy Provent, Frederic Boschetti, Franck Denat, Fabrice Viviani, Cyril Berthet
Publikováno v: Cancer Research. 82:1401-1401
Molecular Radiotherapy (MRT) targeting SSTR2 or PSMA have proven to be highly efficient for the treatment of neuroendocrine or metastatic prostate cancer, respectively. Beyond the leading radiopharmaceutical molecules 177Lu-DOTATATE or 177Lu-PSMA-617
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39b203f4d4cd9bbfebd9d4e96c59bf4e
https://doi.org/10.1158/1538-7445.am2022-1401
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7
Biomimetic, smart and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging
Autor: Pauline Lejault, Joanna Zell, David Monchaud, Francesco Rota Sperti, Thibaut Charbonnier, Ibai E. Valverde, Claire Bernhard
Publikováno v: ACS Chemical Biology
ACS Chemical Biology, American Chemical Society, 2021, 16 (5), pp.905-914. ⟨10.1021/acschembio.1c00111⟩
G-quadruplexes (G4s) continue to gather wide attention in the field of chemical biology as their prevalence in the human genome and transcriptome strongly suggests that they may play key regulatory roles in cell biology. G4-specific, cell-permeable s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d3fca497c73636d61506320b120b59
https://hal.archives-ouvertes.fr/hal-03086822/document
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8
Bridge-Clamp Bis(tetrazine)s with [N] 8 π-Stacking Interactions and Azido- s -Aryl Tetrazines: Two Classes of Doubly Clickable Tetrazines
Autor: Claire Bernhard, Franck Denat, Jean-Cyrille Hierso, Ahmad Daher, Charles H. Devillers, Paul Fleurat-Lessard, Julien Roger, Hélène Cattey, Delphine Vivier, Clève D. Mboyi
Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (3), pp.1149-1154. ⟨10.1002/anie.201911947⟩
Click chemistry at a tetrazine core is useful for bioorthogonal labeling and crosslinking. Introduced here are two new classes of doubly clickable s-aryl tetrazines synthesized by Cu-catalyzed cross-coupling. Homocoupling of o-brominated s-aryl tetra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d298e636394cd807947b7e75b2f14b
https://hal.archives-ouvertes.fr/hal-02469034
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9
Efficient Synthesis of Multifunctional Chelating Agents Based on Tetraazacycloalkanes
Autor: Claire Bernhard, Frédéric Boschetti, Nicolas Sok, Isabelle Baglin, Yoann Rousselin, Pauline Désogère, Franck Denat, Christine Goze
Publikováno v: European Journal of Organic Chemistry. 2018:4762-4768
An efficient route has been developed for the synthesis of multifunctional tetraazacycloalkanes (in particular 1,4,7,10-tetraazacyclotridecane) incorporating an aminomethyl pendant arm on the carbon skeleton. Starting from the appropriate C-functiona
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c0f382162895582c60583eb50293c09
https://doi.org/10.1002/ejoc.201800801
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10
Front Cover: The Scope of Application of Macrocyclic Polyamines Beyond Metal Chelation (Eur. J. Org. Chem. 36/2019)
Autor: Claire Bernhard, Katerina Duskova, Ibai E. Valverde, Anthony Romieu, David Monchaud, Pauline Lejault
Publikováno v: European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2019, 2019 (36), pp.6143-6143. ⟨10.1002/ejoc.201901284⟩
International audience
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e6f5f6dee29a49c15bca8e3690ab26
https://hal.archives-ouvertes.fr/hal-02310168
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