Outcomes and adverse events in older acute lymphoblastic Leukemia patients treated with a pediatric-inspired protocol with Pegylated or native Asparaginase

Autor: Maria Agustina Perusini, Claire Andrews, Eshetu G. Atenafu, Vikas Gupta, Dawn Maze, Andre C. Schuh, Karen WL. Yee, Aniket Bankar, Marta B. Davidson, Guillaume Richard-Carpentier, Steven M. Chan, Jad Sibai, Aaron D. Schimmer, Mark D. Minden, Hassan Sibai

Publikováno v: Hematology, Vol 29, Iss 1 (2024)

This retrospective report presents the outcomes and adverse events (AEs) observed in 73 patients aged 60 years or older diagnosed with Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia (Ph-negative ALL) treated with a pediatric-inspired p

Externí odkaz: https://doaj.org/article/860fe86b5d6c425b93b7c8cf45f165fa

CPX-351 in FLT3-mutated acute myeloid leukemia

Autor: Claire Andrews, Vinod Pullarkat, Christian Recher

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

CPX-351, a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a 1:5 molar ratio, is approved for the treatment of newly diagnosed therapy-related acute myeloid leukemia (AML) or AML with myelodysplasia-related changes. In a pivotal p

Externí odkaz: https://doaj.org/article/1cda4855cb34403eb6a598e66a41608c

Safety of re‐challenging adults with acute lymphoblastic leukemia with PEG‐asparaginase‐induced severe hypertriglyceridemia when treated with a pediatric‐inspired regimen

Autor: Ibrahim Al Nabhani, Claire Andrews, Jad Sibai, Eshetu Atenafu, Taylor Young, Steven M. Chan, Vikas Gupta, Dawn Maze, Aaron D. Schimmer, Andre C. Schuh, Karen Yee, Hassan Sibai

Publikováno v: eJHaem. 4:232-235

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b961302b7bbe81dcef235522559881bd
https://doi.org/10.1002/jha2.607

Real-World Outcomes and Adverse Events of Elderly Patients with Ph-Negative Acute Lymphoblastic Leukemia Treated with a Pediatric-Inspired Protocol

Autor: Maria Agustina Perusini, Jad Sibai, Eshetu G. Atenafu, Aniket Bankar, Mark D. Minden, Vikas Gupta, Dawn Maze, Marta B. Davidson, Steven M. Chan, Aaron D. Schimmer, Guillaume Richard-Carpentier, Josephine Anne Lucero, Claire Andrews, Dennis Dong Hwan Kim, Karen Yee, Andre C. Schuh, Hassan Sibai

Publikováno v: Blood. 140:6039-6041

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::061ab8e76d8890d364dce3646dd49867
https://doi.org/10.1182/blood-2022-169406

Genome sequencing with gene panel-based analysis for rare inherited conditions in a publicly funded healthcare system: implications for future testing

Autor: Lynne J, Hocking, Claire, Andrews, Christine, Armstrong, Morad, Ansari, David, Baty, Jonathan, Berg, Therese, Bradley, Caroline, Clark, Austin, Diamond, Jill, Doherty, Anne, Lampe, Ruth, McGowan, David J, Moore, Dawn, O'Sullivan, Andrew, Purvis, Javier, Santoyo-Lopez, Paul, Westwood, Michael, Abbott, Nicola, Williams, Timothy J, Aitman, Margo, Whiteford

Publikováno v: Hocking, L J, Andrews, C, Armstrong, C, Ansari, M, Baty, D, Berg, J, Bradley, T, Clark, C, Diamond, A, Doherty, J, Lampe, A, McGowan, R, Moore, D J, O'Sullivan, D, Purvis, A, Santoyo-Lopez, J, Westwood, P, Abbott, M, Williams, N & Aitman, T J & Miedzybrodzka, Z 2022, ' Genome sequencing with gene panel-based analysis for rare inherited conditions in a publicly funded healthcare system: implications for future testing ', European Journal of Human Genetics, vol. 31 . https://doi.org/10.1038/s41431-022-01226-3

NHS genetics centres in Scotland sought to investigate the Genomics England 100,000 Genomes Project diagnostic utility to evaluate genome sequencing for in rare, inherited conditions. Four regional services recruited 999 individuals from 394 families

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09a3b01751706f954ef04300960a4c0
https://pubmed.ncbi.nlm.nih.gov/36474026