Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Clair L Alvino"'
Autor:
Clair L Alvino, Shee Chee Ong, Kerrie A McNeil, Carlie Delaine, Grant W Booker, John C Wallace, Briony E Forbes
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27488 (2011)
BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function. IGF-II binds both the insulin-like growth factor receptor (IGF-1R) and insulin
Externí odkaz:
https://doaj.org/article/f7a04f5cd3f64ab49ab50ddae8900dbf
Autor:
Pierre De Meyts, E. Yvonne Jones, James Brown, Terrance D. Mulhern, Carlie Delaine, Clair L. Alvino, Lisbeth Gauguin, Briony E. Forbes, Kerrie A. McNeil, John C. Wallace
The mammalian insulin-like growth factor (IGF)-II/cation-independent mannose 6-phosphate receptor (IGF2R) binds IGF-II with high affinity. By targeting IGF-II to lysosomal degradation, it plays a role in the maintenance of correct IGF-II levels in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be700f2dcb4ed2c38d8565c93702ab7
https://ora.ox.ac.uk/objects/uuid:9b068b68-2f80-42e7-a3ab-fd1863331270
https://ora.ox.ac.uk/objects/uuid:9b068b68-2f80-42e7-a3ab-fd1863331270
Autor:
Clair L. Alvino, Lisbeth Gauguin, Pierre De Meyts, Briony E. Forbes, Kerrie A. McNeil, Carlie Delaine, John C. Wallace
Publikováno v:
Journal of Biological Chemistry. 283:20821-20829
Current evidence supports a binding model in which the insulin molecule contains two binding surfaces, site 1 and site 2, which contact the two halves of the insulin receptor. The interaction of these two surfaces with the insulin receptor results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4c3d22435ac34b2e3d823cce879948
https://doi.org/10.1074/jbc.m802620200
https://doi.org/10.1074/jbc.m802620200
Publikováno v:
Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 22(5)
Insulin-like growth factors (IGF-I and IGF-II), and insulin are evolutionarily conserved hormonal regulators of eukaryotic growth and development. Through interactions with their cognate receptors, all three molecules can influence cellular growth, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9870d78ccb7785c609a6d0a7a9ddab19
https://pubmed.ncbi.nlm.nih.gov/22698731
https://pubmed.ncbi.nlm.nih.gov/22698731
Autor:
John C. Wallace, Jonathan Whittaker, Carlie Delaine, Grant W. Booker, Briony E. Forbes, Shee Chee Ong, Kerrie A. McNeil, Clair L. Alvino
Very little is known about the residues important for the interaction of insulin-like growth factor II (IGF-II) with the type 1 IGF receptor (IGF-1R) and the insulin receptor (IR). Insulin, to which IGF-II is homologous, is proposed to cross-link opp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e28f2b4e58a6ed1e291ca7228df1665
https://europepmc.org/articles/PMC2658059/
https://europepmc.org/articles/PMC2658059/
Autor:
Carlie Delaine, John C. Wallace, Grant W. Booker, Clair L. Alvino, Briony E. Forbes, Kerrie A. McNeil, Shee Chee Ong
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27488 (2011)
PLoS ONE
PLoS ONE
Background Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function. IGF-II binds both the insulin-like growth factor receptor (IGF-1R) and insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878e7935ba19b3f995bc3c4cd3f27b50
https://doi.org/10.1371/journal.pone.0027488
https://doi.org/10.1371/journal.pone.0027488
Autor:
Clair L. Alvino, Grant W. Booker, Shee Chee Ong, Kerrie A. McNeil, Briony E. Forbes, John C. Wallace
Publikováno v:
Growth Hormone & IGF Research. 20:S56
demonstrated the role of the IGF system in the regulation of trophoblast proliferation and survival and alterations in the IGF ligands or the receptors could have implications in the pathogenesis of trophoblastic diseases. The aim of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e8a2103f879ef7258ad0429a2b39371
https://doi.org/10.1016/s1096-6374(10)70146-5
https://doi.org/10.1016/s1096-6374(10)70146-5
Publikováno v:
Growth Hormone & IGF Research. 16:S18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a23f95cb86becbf77d997c42e424bc1
https://doi.org/10.1016/s1096-6374(07)70236-8
https://doi.org/10.1016/s1096-6374(07)70236-8
Publikováno v:
Growth Hormone & IGF Research. 16:S25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbbd870c0dbd7442ed3005ab5f757771
https://doi.org/10.1016/s1096-6374(07)70259-9
https://doi.org/10.1016/s1096-6374(07)70259-9