Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Clair Hartmann"'
Autor:
Eva-Maria Wolfschmitt, Melanie Hogg, Josef Albert Vogt, Fabian Zink, Ulrich Wachter, Felix Hezel, Xiaomin Zhang, Andrea Hoffmann, Michael Gröger, Clair Hartmann, Holger Gässler, Thomas Datzmann, Tamara Merz, Andreas Hellmann, Christine Kranz, Enrico Calzia, Peter Radermacher, David Alexander Christian Messerer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSodium thiosulfate (Na2S2O3), an H2S releasing agent, was shown to be organ-protective in experimental hemorrhage. Systemic inflammation activates immune cells, which in turn show cell type-specific metabolic plasticity with modifications
Externí odkaz:
https://doaj.org/article/6aec3c551b6a4003a7c9b5ece2534655
Autor:
Julien Demiselle, Enrico Calzia, Clair Hartmann, David Alexander Christian Messerer, Pierre Asfar, Peter Radermacher, Thomas Datzmann
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract There is an ongoing discussion whether hyperoxia, i.e. ventilation with high inspiratory O2 concentrations (FIO2), and the consecutive hyperoxaemia, i.e. supraphysiological arterial O2 tensions (PaO2), have a place during the acute managemen
Externí odkaz:
https://doaj.org/article/2152f07201ee41679d4cfb5d4e6cad90
Autor:
Xiaomin Zhang, Fabian Zink, Felix Hezel, Josef Vogt, Ulrich Wachter, Martin Wepler, Maurizio Loconte, Christine Kranz, Andreas Hellmann, Boris Mizaikoff, Peter Radermacher, Clair Hartmann
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss S1, Pp 1-14 (2020)
Abstract Immune cell activation leads to the acquisition of new functions, such as proliferation, chemotaxis, and cytokine production. These functional changes require continuous metabolic adaption in order to sustain ATP homeostasis for sufficient h
Externí odkaz:
https://doaj.org/article/a31a16de3a14400f9f2e336d85df91cf
Autor:
Tamara Merz, Nicole Denoix, Martin Wepler, Holger Gäßler, David A. C. Messerer, Clair Hartmann, Thomas Datzmann, Peter Radermacher, Oscar McCook
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss S1, Pp 1-16 (2020)
Abstract This review addresses the plausibility of hydrogen sulfide (H2S) therapy for acute lung injury (ALI) and circulatory shock, by contrasting the promising preclinical results to the present clinical reality. The review discusses how the narrow
Externí odkaz:
https://doaj.org/article/16410610cb7548f4b2df983ecf0534c4
Autor:
Martin Wepler, Jonathan M. Preuss, Tamara Merz, Clair Hartmann, Ulrich Wachter, Oscar McCook, Josef Vogt, Sandra Kress, Michael Gröger, Marina Fink, Angelika Scheuerle, Peter Möller, Enrico Calzia, Ute Burret, Peter Radermacher, Jan P. Tuckermann, Sabine Vettorazzi
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Background: Sepsis, that can be modeled by LPS injections, as an acute systemic inflammation syndrome is the most common cause for acute lung injury (ALI). ALI induces acute respiratory failure leading to hypoxemia, which is often associated with mul
Externí odkaz:
https://doaj.org/article/e7eb751a8d3c4d92a79ccbbb51d3408e
Autor:
Tamara Merz, Britta Lukaschewski, Daniela Wigger, Aileen Rupprecht, Martin Wepler, Michael Gröger, Clair Hartmann, Matthew Whiteman, Csaba Szabo, Rui Wang, Christiane Waller, Peter Radermacher, Oscar McCook
Publikováno v:
Intensive Care Medicine Experimental, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Background Both the hydrogen sulfide/cystathionine-γ-lyase (H2S/CSE) and oxytocin/oxytocin receptor (OT/OTR) systems have been reported to be cardioprotective. H2S can stimulate OT release, thereby affecting blood volume and pressure regula
Externí odkaz:
https://doaj.org/article/75043ece5c854d7c92ce5cc6f3e917ed
Autor:
Julien Demiselle, Martin Wepler, Clair Hartmann, Peter Radermacher, Frédérique Schortgen, Ferhat Meziani, Mervyn Singer, Valérie Seegers, Pierre Asfar, the HYPER2S investigators
Publikováno v:
Annals of Intensive Care, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Criteria for the Sepsis-3 definition of septic shock include vasopressor treatment to maintain a mean arterial pressure > 65 mmHg and a lactate concentration > 2 mmol/L. The impact of hyperoxia in patients with septic shock using
Externí odkaz:
https://doaj.org/article/6ce492b3e67f430d81ddee5f364c114b
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
The role of nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) as poisonous gases is well-established. However, they are not only endogenously produced but also, at low concentrations, exert beneficial effects, such as anti-inflammat
Externí odkaz:
https://doaj.org/article/648834820d3a44bab2a77e290bdc9745
Autor:
David A. C. Messerer, Enrico Calzia, Peter Radermacher, Thomas Datzmann, Clair Hartmann, Pierre Asfar, Julien Demiselle
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-9 (2021)
There is an ongoing discussion whether hyperoxia, i.e. ventilation with high inspiratory O2 concentrations (FIO2), and the consecutive hyperoxaemia, i.e. supraphysiological arterial O2 tensions (PaO2), have a place during the acute management of circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff80d44d0fb968b1e5ad273b5b8d692e
https://doaj.org/article/2152f07201ee41679d4cfb5d4e6cad90
https://doaj.org/article/2152f07201ee41679d4cfb5d4e6cad90
Autor:
Pierre Asfar, Enrico Calzia, Peter Radermacher, David A. C. Messerer, Thomas Datzmann, Clair Hartmann, Julien Demiselle
Publikováno v:
Kompass Neumología. 3:85-91
Actualmente se discute si la hiperoxia – es decir, la ventilación con altas concentraciones de O2 inspirado (FIO2) – y la hiperoxemia resultante – o sea, la existencia de tensiones arteriales de O2 (PaO2) suprafisiológicas – tienen utilidad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a0d4984f88a25850257451afe079ce
https://doi.org/10.1159/000519761
https://doi.org/10.1159/000519761