Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Clair Crewe"'
Autor:
Toshiharu Onodera, Dae-Seok Kim, Risheng Ye, May-Yun Wang, Shiuhwei Chen, Bianca C. Field, Leon Straub, Xue-Nan Sun, Chao Li, Charlotte Lee, Megan Paredes, Clair Crewe, Shangang Zhao, Christine M. Kusminski, Ruth Gordillo, Philipp E. Scherer
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101821- (2023)
The disease progression of the metabolic syndrome is associated with prolonged hyperlipidemia and insulin resistance, eventually giving rise to impaired insulin secretion, often concomitant with hypoadiponectinemia. As an adipose tissue derived hormo
Externí odkaz:
https://doaj.org/article/2a4c59c398c7494fb3ba2aafae8e0020
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 5, Pp 284-297 (2022)
Abstract Extracellular vesicles (EVs), exosomes and microvesicles, is a burgeoning field of biological and biomedical research that may change our understanding of cell communication in plants and animals while holding great promise for the diagnosis
Externí odkaz:
https://doaj.org/article/42d059e1a1644182b444ddbf1a59fc3b
Autor:
Clair Crewe
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-3 (2022)
Recent developments in adipose tissue-derived extracellular vesicle (EV) research is highlighted, assessing current adipose tissue EV research strategies and obstacles the field faces.
Externí odkaz:
https://doaj.org/article/8b3872424b3846a8908b915658fc837c
Autor:
Yi Zhu, Na Li, Mingyang Huang, Mason Bartels, Sophie Dogné, Shangang Zhao, Xi Chen, Clair Crewe, Leon Straub, Lavanya Vishvanath, Zhuzhen Zhang, Mengle Shao, Yongjie Yang, Christy M. Gliniak, Ruth Gordillo, Gordon I. Smith, William L. Holland, Rana K. Gupta, Bingning Dong, Nathalie Caron, Yong Xu, Yucel Akgul, Samuel Klein, Philipp E. Scherer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Hyaluronan is a naturally occurring linear polysaccharide that together with collagens, enzymes, and glycoproteins forms the extracellular matrix. Here the authors show that adipose tissue overproduction of Hyaluronan reduces fat accumulation in mice
Externí odkaz:
https://doaj.org/article/d5d6f30432264ee3a4a2783133e16a29
Autor:
Rong Yang, Eunice E Lee, Jiwoong Kim, Joon H Choi, Elysha Kolitz, Yating Chen, Clair Crewe, Nicholas J H Salisbury, Philipp E Scherer, Clay Cockerell, Taylor R Smith, Leslie Rosen, Louisa Verlinden, Denise A Galloway, Christopher B Buck, Mariet C Feltkamp, Christopher S Sullivan, Richard C Wang
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009582 (2021)
Circular RNAs (circRNAs) are a conserved class of RNAs with diverse functions, including serving as messenger RNAs that are translated into peptides. Here we describe circular RNAs generated by human polyomaviruses (HPyVs), some of which encode varia
Externí odkaz:
https://doaj.org/article/4eb50517857d4f2caf9eb025a5a0ebc2
Autor:
Nolwenn Joffin, Christy M. Gliniak, Jan-Bernd Funcke, Vivian A. Paschoal, Clair Crewe, Shiuhwei Chen, Ruth Gordillo, Christine M. Kusminski, Da Young Oh, Werner J. Geldenhuys, Philipp E. Scherer
Publikováno v:
Nature Metabolism. 4:1474-1494
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a008100f36dc1ec556609e9b99e087ed
https://doi.org/10.1038/s42255-022-00664-z
https://doi.org/10.1038/s42255-022-00664-z
Autor:
Jessica M. Sabio, Clair Crewe
Publikováno v:
Thermogenic Fat ISBN: 9781071631669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19358de521980677d1c528904d55dd2e
https://doi.org/10.1007/978-1-0716-3167-6_19
https://doi.org/10.1007/978-1-0716-3167-6_19
Autor:
Clair Crewe, Shiuhwei Chen, Dawei Bu, Christy M. Gliniak, Ingrid Wernstedt Asterholm, Xin Xin Yu, Nolwenn Joffin, Camila O. de Souza, Jan-Bernd Funcke, Da Young Oh, Oleg Varlamov, Jacob J. Robino, Ruth Gordillo, Philipp E. Scherer
Caveolin-1 (cav1) is an important structural and signaling component of plasma membrane invaginations called caveolae and is abundant in adipocytes. As previously reported, adipocyte-specific ablation of the cav1 gene (ad-cav1KO mouse) does not resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931fd98b67fdf48c916b91e341dd076a
https://doi.org/10.2337/figshare.20359713.v1
https://doi.org/10.2337/figshare.20359713.v1
Autor:
Philipp E. Scherer, Clair Crewe
Publikováno v:
Reviews in Endocrine and Metabolic Disorders. 23:61-69
Functional adipose tissue is essential for homeostatic maintenance of systemic metabolism. As such, adipose tissue dysfunction, like that seen in the obese state, directly contributes to system-wide pathological metabolism, leading to the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b0a1e35b2075417d6f8c85764b2c478
https://doi.org/10.1007/s11154-020-09625-x
https://doi.org/10.1007/s11154-020-09625-x
Autor:
Thomas S. Morley, Clair Crewe, Yu An, Ruth Gordillo, Joshua A. Johnson, Alexandra L. Ghaben, Ricardo J. Samms, Nolwenn Joffin, Toshiharu Onodera, Philipp E. Scherer, Christine M. Kusminski, William L. Holland, Andrew C. Adams
Publikováno v:
Diabetes
Obesity-associated type 2 diabetes mellitus (T2DM) entails insulin resistance and loss of β-cell mass. Adipose tissue mitochondrial dysfunction is emerging as a key component in the etiology of T2DM. Identifying approaches to preserve mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87058a97126de601f66ace31fe0c3063
https://doi.org/10.2337/db19-0327
https://doi.org/10.2337/db19-0327