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Persistent CAD activity in memory CD8⁺ T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge.

Autor: Claiborne, Michael D., Sengupta, Srona, Zhao, Liang, Arwood, Matthew L., Sun, Im-Meng, Wen, Jiayu, Thompson, Elizabeth A., Mitchell-Flack, Marisa, Laiho, Marikki, Powell, Jonathan D.

Publikováno v: Science Immunology; 2022, Vol. 7 Issue 71, p1-14, 14p

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Serendipitous Discovery of T Cell-Produced KLK1b22 as a Regulator of Systemic Metabolism.

Autor: Arwood ML; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Sun IH; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Patel CH; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Sun IM; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Oh MH; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Bettencourt IA; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Claiborne MD; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Chan-Li Y; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Zhao L; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Waickman AT; State University of New York Upstate Medical University, Syracuse, NY., Mavrothalassitis O; Department of Anesthesia, University of California, San Francisco School of Medicine, San Francisco, CA., Wen J; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD., Aja S; Center for Metabolism and Obesity Research, Johns Hopkins Medicine, Baltimore, MD.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD., Powell JD; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney-Kimmel Comprehensive Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.

Publikováno v: ImmunoHorizons [Immunohorizons] 2023 Jun 01; Vol. 7 (6), pp. 493-507.