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Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B.

Autor: Touvier T; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Veneri FA; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Claessens A; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Ferri C; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Mastrangelo R; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Sorgiati N; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Bianchi F; Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Valenzano S; Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.; Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milan, 20157 Milan, Italy.; University of Camerino, Center for Neuroscience, 62032 Camerino, Italy., Del Carro U; Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Rivellini C; Division of Neuroscience, IRCCS Ospedale San Raffaele, 20132 Milan, Italy., Duong P; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA., Shy ME; Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242 USA., Kelly JW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Svaren J; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA., Wiseman RL; Department of Molecular and Cellular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., D'Antonio M; Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 02. Date of Electronic Publication: 2024 Feb 02.