Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claes Holmgren"'
Autor:
Ben Davis, Giulia Opassi, Darius Vagrys, U. Helena Danielson, Iwan J. P. de Esch, Anna Moberg, P. Boronat, Roderick E. Hubbard, Doreen Dobritzsch, Claes Holmgren, Jacqueline E. van Muijlwijk-Koezen, David J. Hamilton, Edward A. FitzGerald, Peter O'Brien, Daniela Cederfelt, Hanna F. Klein, Maikel Wijtmans, Vladimir O. Talibov, Mia Abramsson, Maria T. Lindgren
Publikováno v:
bioRxiv, 2020. Cold Spring Harbor Laboratory Press
Fitzgerald, E, Hamilton, D, Boronat, P, van Muijlwijk-Koezen, J E, Wijtmans, M, de Esch, IJP & Danielson, H 2020, ' Multiplexed experimental strategies for fragment library screening using SPR biosensors ', bioRxiv, vol. 2020 . https://doi.org/10.1101/2020.12.23.424167
Fitzgerald, E, Hamilton, D, Boronat, P, van Muijlwijk-Koezen, J E, Wijtmans, M, de Esch, IJP & Danielson, H 2020, ' Multiplexed experimental strategies for fragment library screening using SPR biosensors ', bioRxiv, vol. 2020 . https://doi.org/10.1101/2020.12.23.424167
Surface plasmon resonance biosensor technology (SPR) is ideally suited for fragment-based lead discovery. However, generally suitable experimental procedures or detailed protocols are lacking, especially for structurally or physico-chemically challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ac1e8fd204791f50bf282acb941200
https://doi.org/10.1101/2020.12.23.424167
https://doi.org/10.1101/2020.12.23.424167
Autor:
Anita Göndör, Catharina Larsson, Monira Akhtar, Tomas J. Ekström, Claes Holmgren, Chandrasekhar Kanduri, Mattias Vesterlund
Publikováno v:
International Journal of Oncology
The fetal transcription factor PLAG1 is found to be overexpressed in cancers, and has been suggested to bind the insulin like growth factor 2 (IGF2) P3 promoter, and to activate the IGF2 gene. The expression of IGF2 has partly been linked to loss of
Autor:
Erik Ullerås, Rolf Ohlsson, Chandrasekhar Kanduri, Claes Holmgren, Vinod Pant, Victor V. Lobanenkov, Gary C. Franklin, Vasudeva Ginjala
Publikováno v:
Journal of Biological Chemistry. 277:5707-5710
The 5′-flank of the H19 gene harbors a differentially methylated imprinting control region that represses the maternally derived Igf2 and paternally derivedH19 alleles. Here we show that the H19imprinting control region (ICR) is a potent silencer w
Publikováno v:
The Journal of biological chemistry. 278(11)
The mechanisms underlying the phenomenon of genomic imprinting are poorly understood. Accumulating evidence suggests that imprinting control regions (ICR) associated with the imprinted genes play an important role in creation of imprinted expression
Autor:
Vasudeva, Ginjala, Claes, Holmgren, Erik, Ullerås, Chandrasekhar, Kanduri, Vinod, Pant, Victor, Lobanenkov, Gary, Franklin, Rolf, Ohlsson
Publikováno v:
The Journal of biological chemistry. 277(8)
The 5'-flank of the H19 gene harbors a differentially methylated imprinting control region that represses the maternally derived Igf2 and paternally derived H19 alleles. Here we show that the H19 imprinting control region (ICR) is a potent silencer w
Autor:
Rituparna Mukhopadhya, Victor V. Lobanenkov, Andrew Ward, Meena Kanduri, Chandrasekhar Kanduri, Claes Holmgren, Ghislaine Dell, Rolf Ohlsson
Publikováno v:
Current biology : CB. 11(14)
The differentially methylated 5′-flank of the mouse H19 gene unidirectionally regulates the communication between enhancer elements and gene promoters and presumably represses maternal Igf2 expression in vivo [1–6]. The specific activation of the
Autor:
Chandra Kanduri, Rolf Ohlsson, Vasudeva Ginjala, Gary C. Franklin, Marcel Pilartz, Claes Holmgren, Ragnar Mattsson, Liang Liu, Erik Ullerås, Meena Kanduri
Publikováno v:
Current biology : CB. 10(8)
Background: During mouse prenatal development, the neighbouring insulin-like growth factor II ( Igf2 ) and H19 loci are expressed monoallelically from the paternal and maternal alleles, respectively. Identical spatiotemporal expression patterns and e