Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Claes Wadelius"'
Autor:
Casimiro Castillejo-López, José Ramón Bárcenas-Walls, Marco Cavalli, Anders Larsson, Claes Wadelius
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Genome-wide association studies (GWAS) have identified genetic variants linked to fat metabolism and related traits, but rarely pinpoint causative variants. This limitation arises from GWAS not considering functional implications
Externí odkaz:
https://doaj.org/article/944abdab779e4c4c8c9f7c32ec909db4
Autor:
Amanda Raine, Anders Lundmark, Alva Annett, Ann-Christin Wiman, Marco Cavalli, Claes Wadelius, Claudia Bergin, Jessica Nordlund
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract DNA methylation is a central epigenetic mark that has diverse roles in gene regulation, development, and maintenance of genome integrity. 5 methyl cytosine (5mC) can be interrogated at base resolution in single cells by using bisulfite seque
Externí odkaz:
https://doaj.org/article/5100dbe745fa4f8faabe411573eedaf9
Autor:
Casimiro Castillejo-Lopez, Milos Pjanic, Anna Chiara Pirona, Susanne Hetty, Martin Wabitsch, Claes Wadelius, Thomas Quertermous, Erik Arner, Erik Ingelsson
Publikováno v:
iScience, Vol 20, Iss , Pp 42-59 (2019)
Summary: We combined CAGE sequencing in human adipocytes during differentiation with data from genome-wide association studies to identify an enhancer in the SNX10 locus on chromosome 7, presumably involved in body fat distribution. Using reporter as
Externí odkaz:
https://doaj.org/article/f873f81f776f44f782763874e3c8e5fd
Autor:
Marco Cavalli, Nicholas Baltzer, Gang Pan, José Ramón Bárcenas Walls, Karolina Smolinska Garbulowska, Chanchal Kumar, Stanko Skrtic, Jan Komorowski, Claes Wadelius
Publikováno v:
Human Genomics, Vol 13, Iss 1, Pp 1-8 (2019)
Abstract Background Genome-wide association studies (GWAS) of diseases and traits have found associations to gene regions but not the functional SNP or the gene mediating the effect. Difference in gene regulatory signals can be detected using chromat
Externí odkaz:
https://doaj.org/article/b886c2ddfcee404e937050aea5969752
Autor:
Pär Hallberg, Hans Smedje, Niclas Eriksson, Hugo Kohnke, Makrina Daniilidou, Inger Öhman, Qun-Ying Yue, Marco Cavalli, Claes Wadelius, Patrik K.E. Magnusson, Anne-Marie Landtblom, Mia Wadelius
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 595-604 (2019)
Background: The incidence of narcolepsy rose sharply after the swine influenza A (H1N1) vaccination campaign with Pandemrix. Narcolepsy is an immune-related disorder with excessive daytime sleepiness. The most frequent form is strongly associated wit
Externí odkaz:
https://doaj.org/article/920b24431bea4d3ea6c999f1e808a40e
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Long-chain polyunsaturated fatty acids (LC-PUFAs) influence human health in several areas, including cardiovascular disease, diabetes, fatty liver disease, and cancer. ELOVL2 encodes one of the key enzymes in the in vivo synthesis of LC-PUFA
Externí odkaz:
https://doaj.org/article/086bb7c3153e48ddad39eb960e84dfb1
Autor:
Komorowski, Mateusz Garbulowski, Karolina Smolinska, Uğur Çabuk, Sara A. Yones, Ludovica Celli, Esma Nur Yaz, Fredrik Barrenäs, Klev Diamanti, Claes Wadelius, Jan
Publikováno v:
Cancers; Volume 14; Issue 4; Pages: 1014
Gliomas develop and grow in the brain and central nervous system. Examining glioma grading processes is valuable for improving therapeutic challenges. One of the most extensive repositories storing transcriptomics data for gliomas is The Cancer Genom
Autor:
Ulf Risérus, Chanchal Kumar, Maria J. Pereira, Claes Wadelius, Klev Diamanti, Gang Pan, Håkan Ahlström, Joel Kullberg, Jan W. Eriksson, Marco Cavalli, Stanko Skrtic, Robin Visvanathar, Jan Komorowski
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Alteration of various metabolites has been linked to type 2 diabetes (T2D) and insulin resistance. However, identifying significant associations between metabolites and tissue-specific phenotypes requires a multi-omics approach. In a cohort of 42 sub
Autor:
Mateusz, Garbulowski, Karolina, Smolinska, Uğur, Çabuk, Sara A, Yones, Ludovica, Celli, Esma Nur, Yaz, Fredrik, Barrenäs, Klev, Diamanti, Claes, Wadelius, Jan, Komorowski
Publikováno v:
Cancers. 14(4)
Gliomas develop and grow in the brain and central nervous system. Examining glioma grading processes is valuable for improving therapeutic challenges. One of the most extensive repositories storing transcriptomics data for gliomas is The Cancer Genom
Autor:
Claes Wadelius, Claudia Bergin, Alva Annett, Marco Cavalli, Anders Lundmark, Amanda Raine, Ann-Christin Wiman, Jessica Nordlund
SummaryDNA methylation is a central epigenetic mark that has diverse roles in gene regulation, development, and maintenance of genome integrity. 5 methyl cytosine (5mC) can be interrogated at base resolution in single cells by using bisulfite sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2eff4f07cbae8249fe9c197c90ea34e
https://doi.org/10.1101/2021.10.14.464375
https://doi.org/10.1101/2021.10.14.464375