Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Claes Öhlén"'
Autor:
Junko Morimoto, Carla Fowler, Michelle L. Dossett, Philip D. Greenberg, Maria Z. Huang, Ryan M. Teague, Xiaoxia Tan, Claes Öhlén, Eric S. Huseby
Publikováno v:
Immunity. 28(5):662-674
SummaryCD8+ T cell tolerance, although essential for preventing autoimmunity, poses substantial obstacles to eliciting immune responses to tumor antigens, which are generally overexpressed normal proteins. Development of effective strategies to overc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3463282f09b54200e4b5e68d68cf20
Publikováno v:
The Journal of Immunology. 178:6849-6860
Cross-presentation of normal self and candidate tumor Ags by bone marrow (BM)-derived APCs that have not been activated has been demonstrated as a major mechanism contributing to acquisition of tolerance by mature T cells that first encounter an Ag i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda22bc973788e593d6ff036231e4415
https://doi.org/10.4049/jimmunol.178.11.6849
https://doi.org/10.4049/jimmunol.178.11.6849
Autor:
Gilbert Jay, Lars Ährlund-Richter, George A. Scangos, Charles Bieberich, Klas Kärre, Petter Höglund, Hans-Gustaf Ljunggren, George Klein, Claes Öhlén
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a281759eb4ed691890892c20911ae6dc
https://doi.org/10.1159/000416302
https://doi.org/10.1159/000416302
Autor:
Ulf Dittmer, Hong He, Anke R. M. Olbrich, Shimon Sakaguchi, Ronald J. Messer, Simone Schimmer, Ingunn M. Stromnes, Karin E. Peterson, Kim J. Hasenkrug, Leonard H. Evans, Philip D. Greenberg, Claes Öhlén, Guojun Yang, Michihiro Iwashiro
Publikováno v:
Immunity. 20:293-303
The establishment of viral persistence generally requires evasion of the host CD8(+) T cell response. Here we describe a form of evasion wherein the CD8(+) T cells are fully capable of recognizing their cognate antigen but their effector functions ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454d06c028fa73b4a1d148217329d32e
https://doi.org/10.1016/s1074-7613(04)00054-8
https://doi.org/10.1016/s1074-7613(04)00054-8
Publikováno v:
The Journal of Experimental Medicine
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) characterized by plaques of infiltrating CD4+ and CD8+ T cells. Studies of MS and experimental autoimmune encephalomyelitis (EAE), an animal model of MS, focus on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbd4bd59176bb75ac4154a2f1508420
https://doi.org/10.1084/jem.194.5.669
https://doi.org/10.1084/jem.194.5.669
Autor:
Rickard Glas, Klas Kärre, Maija-Leena Eloranta, Lars Franksson, Clas Une, Anders Örn, Claes Öhlén
Publikováno v:
The Journal of Experimental Medicine
Natural killer (NK) cells can spontaneously lyse certain virally infected and transformed cells. However, early in immune responses NK cells are further activated and recruited to tissue sites where they perform effector functions. This process is de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2debbb26b88a1e99b43ca675783a4a7
https://doi.org/10.1084/jem.191.1.129
https://doi.org/10.1084/jem.191.1.129
Publikováno v:
The Journal of Experimental Medicine
Beta 2-Microglobulin-deficient (beta 2m -/-) mice are reported to lack cell surface expression of major histocompatibility complex (MHC) class I molecules, CD8+ T cells, and the ability to mount MHC class I-specific T cell responses. We have observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0dc22d1f8b8909a44b9d9510913aac
http://europepmc.org/articles/PMC2191377
http://europepmc.org/articles/PMC2191377
Publikováno v:
International Journal of Cancer. 47:38-44
Experiments with mutant cell lines have underscored the role for peptide in maintenance of the structure of major histocompatibility complex (MHC) class-I molecules. The class-I molecules act as receptors for antigenic and "self" peptides derived fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5d173d05612e25772ad7f7505773e6
https://doi.org/10.1002/ijc.2910470711
https://doi.org/10.1002/ijc.2910470711
Publikováno v:
The Journal of Experimental Medicine
The mechanism behind natural tumor resistance conveyed by a H-2Dd transgene to C57Bl/6 (B6) mice was investigated. Transgenic D8 mice were more efficient than control mice in natural killer (NK) cell mediated rapid elimination of intravenously inocul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b3c2e7712dc0eae04105ca502372ab
http://europepmc.org/articles/PMC2118914
http://europepmc.org/articles/PMC2118914