Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Claas Otto"'
Autor:
T Schneider, Frédéric Baribaud, Bridget A. Puffer, Zhiwei Chen, Jan Münch, Claas Otto, Thomas Gramberg, Heike Hofmann, Kerstin Mätz-Rensing, Christiane Stahl-Hennig, Jonathan L. Heeney, George J. Leslie, Peter ten Haaft, Frank Kirchhoff, Jacqueline D. Reeves, Andrea Marzi, Sheriff Aziz, Stefan Pöhlmann, Nicole Stolte, Robert W. Doms
Publikováno v:
Virology. 360:275-285
Sexually transmitted HIV-1 strains utilize the chemokine receptor CCR5 for viral entry and inhibitors targeting this coreceptor offer great promise for antiretroviral therapy. They also raise the question, however, whether viral variants exhibiting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c9d2db1725663e81087243659fab8c
https://doi.org/10.1016/j.virol.2006.10.020
https://doi.org/10.1016/j.virol.2006.10.020
Autor:
Steffen Lorenz, Claas Otto, George J. Leslie, Silke Meister, Frank Kirchhoff, Bridget A. Puffer, Mandy Krumbiegel, Armin Papkalla, Jacqueline D. Reeves, Jan Münch, Stefan Pöhlmann, Robert W. Doms, Carl W. Davis, Andrea Marzi
Publikováno v:
Journal of Virology. 78:3223-3232
The V3 loop of the simian immunodeficiency virus (SIV) envelope protein (Env) largely determines interactions with viral coreceptors. To define amino acids in V3 that are critical for coreceptor engagement, we functionally characterized Env variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8e4fcc0057aa9ec298e18f1c16ae9b
https://doi.org/10.1128/jvi.78.7.3223-3232.2004
https://doi.org/10.1128/jvi.78.7.3223-3232.2004
Publikováno v:
Virology. 315(2):292-302
Residues within the highly conserved C3 region of human and simian immunodeficiency virus (HIV, SIV) envelope proteins (Envs) bind directly to the cellular CD4 receptor. However, substitutions of D385, which is critical for CD4 engagement along with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134b73e85e21f4bb01c3790e3620dc03
Publikováno v:
Journal of Virology. 76:8455-8459
We investigated the infectivities and replicative capacities of a large panel of variants of the molecular human immunodeficiency virus type 1 (HIV-1) NL4-3 clone that differ exclusively in the V3 region of the viral envelope glycoprotein and thenefg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f41a39a1cb24cbd141e910b6b87c98e
https://doi.org/10.1128/jvi.76.16.8455-8459.2002
https://doi.org/10.1128/jvi.76.16.8455-8459.2002
Autor:
Sandrine Sarrazin, Louise K. Modis, Philippe Kastner, Taro Fukao, Noushine Mossadegh-Keller, Claas Otto, Estelle Duprez, Laurent Vanhille, Athar Aziz, Susan Chan, Frédéric Mourcin, Michael H. Sieweke
Publikováno v:
Cell
Cell, 2009, 138 (2), pp.300-13. ⟨10.1016/j.cell.2009.04.057⟩
Cell, Elsevier, 2009, 138 (2), pp.300-13. ⟨10.1016/j.cell.2009.04.057⟩
Cell, 2009, 138 (2), pp.300-13. ⟨10.1016/j.cell.2009.04.057⟩
Cell, Elsevier, 2009, 138 (2), pp.300-13. ⟨10.1016/j.cell.2009.04.057⟩
International audience; While hematopoietic stem cell (HSC) self-renewal is well studied, it remains unknown whether distinct control mechanisms enable HSC divisions that generate progeny cells with specific lineage bias. Here, we report that the mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e490333263af296cb6470f1b207fd113
https://www.hal.inserm.fr/inserm-00420157
https://www.hal.inserm.fr/inserm-00420157
Autor:
Ronald T. Hay, Laurent Vanhille, Claas Otto, Silke Tillmanns, Michael H. Sieweke, Youssef Bakri, Camille Du Roure, Ellis Jaffray, Sandrine Sarrazin
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2007, 27 (15), pp.5554-64. ⟨10.1128/MCB.01811-06⟩
Molecular and Cellular Biology, 2007, 27 (15), pp.5554-64. ⟨10.1128/MCB.01811-06⟩
Molecular and Cellular Biology, American Society for Microbiology, 2007, 27 (15), pp.5554-64. ⟨10.1128/MCB.01811-06⟩
Molecular and Cellular Biology, 2007, 27 (15), pp.5554-64. ⟨10.1128/MCB.01811-06⟩
During the execution of differentiation programs, lineage-specific transcription factors are in competition with antagonistic factors that drive progenitor proliferation. Thus, the myeloid transcription factor MafB promotes macrophage differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05f1726a59c11c2cb8148d79dcb8342
https://hal.archives-ouvertes.fr/hal-00165517
https://hal.archives-ouvertes.fr/hal-00165517
Autor:
Sandrine Sarrazin, Peer Mohideen, Noushine Mossadegh, Athar Aziz, Laurent Vanhille, Claas Otto, Youssef Bakri, Michael H. Sieweke, Louise M. Kelly
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26 (18), pp.6808-18. ⟨10.1128/MCB.00245-06⟩
Molecular and Cellular Biology, 2006, 26 (18), pp.6808-18. ⟨10.1128/MCB.00245-06⟩
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26 (18), pp.6808-18. ⟨10.1128/MCB.00245-06⟩
Molecular and Cellular Biology, 2006, 26 (18), pp.6808-18. ⟨10.1128/MCB.00245-06⟩
In the hematopoietic system the bZip transcription factor MafB is selectively expressed at high levels in monocytes and macrophages and promotes macrophage differentiation in myeloid progenitors, whereas a dominant-negative allele can inhibit this pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a66f226bbdf0b6d85d8b21335204052
https://europepmc.org/articles/PMC1592864/
https://europepmc.org/articles/PMC1592864/
Autor:
Martine J. Smit, Paola Casarosa, Henk Timmerman, Wiro M. P. B. Menge, Claas Otto, Frank Kirchhoff, Barbara Moepps, Rosalba Minisini, Aldo Jongejan, Rob Leurs, Thomas Mertens, Jane van Heteren
Publikováno v:
Casarosa, P, Menge, W M P B, Minisini, R, Otto, C, van Heteren, J T, Jongejan, A, Timmerman, H, Moepps, B, Kirchhoff, F, Mertens, T, Smit, M J & Leurs, R 2003, ' Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor ', Journal of Biological Chemistry, vol. 278, no. 7, pp. 5172-8 . https://doi.org/10.1074/jbc.M210033200
Journal of Biological Chemistry, 278(7), 5172-8. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 278(7), 5172-8. American Society for Biochemistry and Molecular Biology Inc.
Human cytomegalovirus (HCMV) encodes a G protein-coupled receptor (GPCR), named US28, which shows homology to chemokine receptors and binds several chemokines with high affinity. US28 induces migration of smooth muscle cells, a feature essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfaf0b6b7aa3919011048877df967d3
https://research.vu.nl/en/publications/52622034-3465-4bb8-a958-19f209838012
https://research.vu.nl/en/publications/52622034-3465-4bb8-a958-19f209838012
Autor:
Silke Meister, Armin Papkalla, Frank Kirchhoff, Stefan Pöhlmann, Mandy Krumbiegel, Claas Otto
Publikováno v:
Virology. (2):287-296
In contrast to human immunodeficiency viruses type 1 and type 2 (HIV-1 and HIV-2, respectively), simian immunodeficiency virus (SIVmac) rarely uses CXCR4 (X4) for efficient entry into target cells. Basic amino acid residues in the V3 loop of HIV Env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b00bcb25740947ee0be45569657952