Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Claartje A. Meddens"'
Autor:
Claartje A. Meddens, Jaap A. Joles, Michal Mokry, Edward E. S. Nieuwenhuis, Dirk J. Duncker, Maarten M. Brandt, Laura Louzao-Martinez, Noortje A.M. van den Dungen, Marianne C. Verhaar, Nico R. Lansu, Caroline Cheng
Publikováno v:
Journal of the American Society of Nephrology, 29(2), 462. American Society of Nephrology
Journal of the American Society of Nephrology, 29(2), 462-476. American Society of Nephrology
Journal of the American Society of Nephrology, 29(2), 462-476. American Society of Nephrology
Genome-wide association studies (GWASs) have identified many genetic risk factors for CKD. However, linking common variants to genes that are causal for CKD etiology remains challenging. By adapting self-transcribing active regulatory region sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166c64e4e6e08c21377c56a9a3ceda41
https://doi.org/10.1681/asn.2016080875
https://doi.org/10.1681/asn.2016080875
Autor:
Hans Clevers, Bart Westendorp, Evelyn S. Hanemaaijer, Claartje A. Meddens, Sabine Middendorp, Miguel Vega, Erik Lijster, Anne Claire Berrens, Edward E. S. Nieuwenhuis, Madeleine J. Bunders, Sinisa Prelic, Michal Mokry, Marjolein Mijnders, Renée R. C. E. Schreurs, Ninke M. Nieuwenhuis, Hemme J. Hijma, Berend A. P. Kooiman, Maaike H. de Vries, Jet van der Spek, Nico Lansu, Suze A. Jansen, Noortje A. M. van den Dungen
Publikováno v:
SSRN Electronic Journal.
Intestinal epithelial cells are capable of mounting adequate antimicrobial inflammatory responses to pathogens, as well as tolerogenic responses to commensals. We studied whether epithelial responsiveness depends on the surface where stimulation take
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447e81c8afdf583c13d4b35033b5ac51
https://doi.org/10.2139/ssrn.3485163
https://doi.org/10.2139/ssrn.3485163
Autor:
Michal Mokry, Edward E. S. Nieuwenhuis, Amy Catharina Johanna van der List, Claartje A. Meddens
Publikováno v:
Gut, 68(5), 928. BMJ Publishing Group
Genome-wide association studies have identified over 200 loci associated with IBD. We and others have recently shown that, in addition to variants in protein-coding genes, the majority of the associated loci are related to DNA regulatory elements (DR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e67343a904263f7b5172ed55376ea7
https://pubmed.ncbi.nlm.nih.gov/30692146
https://pubmed.ncbi.nlm.nih.gov/30692146
Autor:
Magdalena Harakalova, Hassan Foroughi Asl, Noortje A.M. van den Dungen, Edward E. S. Nieuwenhuis, Johan Björkegren, Edwin Cuppen, Folkert W. Asselbergs, Claartje A. Meddens, Michal Mokry, Hemme J. Hijma
Publikováno v:
Genome Biology, 17. BioMed Central
Genome Biology
Genome Biology
Background Genome-wide association studies (GWAS) have revealed many susceptibility loci for complex genetic diseases. For most loci, the causal genes have not been identified. Currently, the identification of candidate genes is predominantly based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db89543026235c55fe2a575a97e95acd
https://doi.org/10.1186/s13059-016-1100-3
https://doi.org/10.1186/s13059-016-1100-3
Autor:
Merlijn Witte, Sabine Middendorp, Hans Teunissen, Hans Clevers, Caroline L. Wiegerinck, Michal Mokry, Edwin Cuppen, Edward E. S. Nieuwenhuis, Claartje A. Meddens
Publikováno v:
Gastroenterology, 146(4), 1040-7. W.B. Saunders Ltd
Background & Aims The contribution of genetic factors to the pathogenesis of inflammatory bowel disease (IBD) has been established by twin, targeted-sequencing, and genome-wide association studies. These studies identified many risk loci, and researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1ae4f917685d974ec45cbc8be83495
https://pure.knaw.nl/portal/en/publications/d6a7b375-72e7-4209-82af-e2f07579a8ff
https://pure.knaw.nl/portal/en/publications/d6a7b375-72e7-4209-82af-e2f07579a8ff
