Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Cláudio Nahum Alves"'
Autor:
Kelly Costa Alves, Carlos Emmerson Ferreira da Costa, Cláudio Márcio Rocha Remédios, Danielle Queiroz Calcagno, Marcelo de Oliveira Lima, José Rogério A. Silva, Cláudio Nahum Alves
Publikováno v:
Molecules, Vol 29, Iss 14, p 3353 (2024)
Indomethacin (INDO) has a mechanism of action based on inhibiting fatty acids cyclooxygenase activity within the inflammation process. The action mechanism could be correlated with possible anticancer activity, but its high toxicity in normal tissues
Externí odkaz:
https://doaj.org/article/f6840adf94434bf488ee780341b216e5
Autor:
Clauber Henrique Souza da Costa, Camila Auad Beltrão de Freitas, Cláudio Nahum Alves, Jerônimo Lameira
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) variant Omicron spread more rapid than the other variants of SARS-CoV-2 virus. Mutations on the Spike (S) protein receptor-binding domain (RBD) are critical for the antibody
Externí odkaz:
https://doaj.org/article/8b82328795f44fd880d7dc7fb8d6a5b8
Autor:
Braian Saimon Frota da Silva, Nelson Rosa Ferreira, Priscila Domingues Alamar, Thiago de Melo e Silva, Wandson Braamcamp de Souza Pinheiro, Lucely Nogueira dos Santos, Cláudio Nahum Alves
Publikováno v:
Molecules, Vol 28, Iss 19, p 6878 (2023)
Brazil nut oil is highly valued in the food, cosmetic, chemical, and pharmaceutical industries, as well as other sectors of the economy. This work aims to use the Fourier transform infrared (FTIR) technique associated with partial least squares regre
Externí odkaz:
https://doaj.org/article/45c3c51ddeb542fa9202af6ae79175e6
Autor:
Camila Auad Beltrão de Freitas, Clauber Henrique Souza Costa, Kauê Santana da Costa, Simone Patrícia Aranha da Paz, José Rogério A. Silva, Cláudio Nahum Alves, Jerônimo Lameira
Publikováno v:
Frontiers in Chemistry, Vol 10 (2023)
Eugenol is a natural compound with well-known repellent activity. However, its pharmaceutical and cosmetic applications are limited, since this compound is highly volatile and thermolabile. Nanoencapsulation provides protection, stability, conservati
Externí odkaz:
https://doaj.org/article/94c31b2946ec42e2adbf0f19a7854203
Autor:
Jéssica de O. Araújo, Silvana Pinheiro, William J. Zamora, Cláudio Nahum Alves, Jerônimo Lameira, Anderson H. Lima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In SARS-CoV-2 replication complex, the Non-structural protein 9 (Nsp9) is an important RNA binding subunit in the RNA-synthesizing machinery. The dimeric forms of coronavirus Nsp9 increase their nucleic acid binding affinity and the N-finger
Externí odkaz:
https://doaj.org/article/7731929feb7a485ab9773988c13d99ca
Autor:
Carla Carolina Ferreira Meneses, Paulo Robson Monteiro de Sousa, Kely Campos Navegantes Lima, Lisa Maria Mendes de Almeida Souza, Waldeci Paraguassu Feio, Cláudio Márcio Rocha Remédios, Jenny Jouin, Philippe Thomas, Olivier Masson, Cláudio Nahum Alves, Jerônimo Lameira, Marta Chagas Monteiro
Publikováno v:
Molecules, Vol 28, Iss 13, p 4973 (2023)
Caffeic acid (CA) exhibits a myriad of biological activities including cardioprotective action, antioxidant, antitumor, anti-inflammatory, and antimicrobial properties. On the other hand, CA presents low water solubility and poor bioavailability, whi
Externí odkaz:
https://doaj.org/article/735bb2a22b0e4d7e85fdb31e517df621
Publikováno v:
ACS Omega, Vol 6, Iss 19, Pp 12507-12512 (2021)
Externí odkaz:
https://doaj.org/article/553af536db4d4551b13ef85c57915d82
Autor:
Lucas Sousa Martins, Reinaldo W. A. Gonçalves, Joana J. S. Moraes, Cláudio Nahum Alves, José Rogério A. Silva
Publikováno v:
Molecules, Vol 27, Iss 23, p 8141 (2022)
Molecular docking, molecular dynamics (MD) simulations and the linear interaction energy (LIE) method were used here to predict binding modes and free energy for a set of 1,2,3-triazole-based KA analogs as potent inhibitors of Tyrosinase (TYR), a key
Externí odkaz:
https://doaj.org/article/21566da51aa0490d844c4dcca9c94456
Autor:
Gueive Astur Pena, Anna Sylmara da Costa Lopes, Sylvano Heleno Salgado de Morais, Lidiane Diniz do Nascimento, Fábio Rogério Rodrigues dos Santos, Kauê Santana da Costa, Cláudio Nahum Alves, Jerônimo Lameira
Publikováno v:
Molecules, Vol 27, Iss 8, p 2519 (2022)
Repellents are compounds that prevent direct contact between the hosts and the arthropods that are vectors of diseases. Several studies have described the repellent activities of natural compounds obtained from essential oils. In addition, these chem
Externí odkaz:
https://doaj.org/article/2d3da9cba4424344ae0f91fac1e24b8d
Autor:
Richelly Cardoso, Renan Valente, Clauber Henrique Souza da Costa, João Lidio da S. Gonçalves Vianez, Kauê Santana da Costa, Fábio Alberto de Molfetta, Cláudio Nahum Alves
Publikováno v:
Molecules, Vol 26, Iss 10, p 2875 (2021)
Tyrosinases belong to the functional copper-containing proteins family, and their structure contains two copper atoms, in the active site, which are coordinated by three histidine residues. The biosynthesis of melanin in melanocytes has two stages de
Externí odkaz:
https://doaj.org/article/7fe69659850b4b719dae97624ec8d1c3