Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Clévia Rosset"'
Autor:
Arthur Bandeira de Mello Garcia, Guilherme Danielski Viola, Bruno da Silveira Corrêa, Taís da Silveira Fischer, Maria Clara de Freitas Pinho, Grazielle Motta Rodrigues, Patricia Ashton-Prolla, Clévia Rosset
Publikováno v:
Genetics and Molecular Biology, Vol 46, Iss 3 suppl 1 (2024)
Abstract Tuberous Sclerosis Complex (TSC) is caused by loss of function germline variants in the TSC1 or TSC2 tumor suppressor genes. Genetic testing for the detection of pathogenic variants in either TSC1 or TSC2 was implemented as a diagnostic crit
Externí odkaz:
https://doaj.org/article/f61dd32b65814e0d97cdb2432e140347
Autor:
Igor Araujo Vieira, Guilherme Danielski Viola, Eduarda Heidrich Pezzi, Thayne Woycinck Kowalski, Bruna Vieira Fernandes, Tiago Finger Andreis, Natascha Bom, Giulianna Sonnenstrahl, Yasminne Marinho de Araújo Rocha, Bruno da Silveira Corrêa, Luiza Mezzomo Donatti, Gabriela dos Santos Sant’Anna, Helena von Eye Corleta, Ilma Simoni Brum, Clévia Rosset, Fernanda Sales Luiz Vianna, Gabriel S. Macedo, Edenir Inez Palmero, Patricia Ashton-Prolla
Publikováno v:
Genetics and Molecular Biology, Vol 46, Iss 3 suppl 1 (2024)
Abstract The TP53 3’UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of polyadenylation and miRNA regulation. Its prevalence is not yet known in all tumor
Externí odkaz:
https://doaj.org/article/1842083036564d94b5d4456d0ea54ce3
Autor:
Grazielle Motta Rodrigues, Maria Clara De Freitas Pinho, Taís da Silveira Fischer, Fabrício Campos, Fernanda de Paris, Fernanda Sales Luiz Vianna, Pâmela Portela da Silva, Patricia Ashton Prolla, Clévia Rosset
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 27, Iss , Pp 102918- (2023)
Introdução: A memória imunológica para o SARS-CoV-2 fornece proteção a longo prazo, podendo ser adquirida por infecção natural ou por vacinação. As células T de memória oferecem suporte para produção de anticorpos (CD4) ou lise celular
Externí odkaz:
https://doaj.org/article/42d61e5640334f5383548900ded36b6b
Autor:
JULIANO ANDRÉ BOQUETT, FERNANDA S.L. VIANNA, NELSON J.R. FAGUNDES, LUCAS SCHROEDER, MARCIA BARBIAN, MARCELO ZAGONEL-OLIVEIRA, TIAGO F. ANDREIS, LUIS CRISTÓVÃO M.S. PÔRTO, JOSÉ ARTUR B. CHIES, LAVINIA SCHULER-FACCINI, PATRICIA ASHTON-PROLLA, CLÉVIA ROSSET
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 95, Iss 3 (2023)
Abstract The coronavirus disease 2019 (COVID-19) mortality rates varied among the states of Brazil during the course of the pandemics. The human leukocyte antigen (HLA) is a critical component of the antigen presentation pathway. Individuals with dif
Externí odkaz:
https://doaj.org/article/10490b44b3cb4b5687fb8982d2071151
Autor:
Juliana Giacomazzi, Patricia Klarmann Ziegelmann, Samanta da Costa, Camila Matzenbacher Bittar, Fernando Mariano Obst, Clévia Rosset, Gabriel S. Macedo, Hugo Bock, Thais Canal, Mari Ines Paese, Jean Lucas Benvenuti, Maria Carolina Buj, Patricia Ashton-Prolla, José Roberto Goldim, Roberta Pozza
Publikováno v:
JCO Global Oncology, Vol , Iss 9 (2023)
PURPOSETo evaluate cancer risk factors among cancer cases and controls from Southern Brazil, to analyze a multigene hereditary panel testing (MGPT, 26 genes) for breast cancer (BC) and colorectal cancer (CCR) cases diagnosed age younger than 50 years
Externí odkaz:
https://doaj.org/article/6ecf9af14bc44aa09e5bcac27e848684
Autor:
Lucas Schroeder, Eniuce Menezes de Souza, Clévia Rosset, Ademir Marques Junior, Juliano André Boquett, Vinicius Francisco Rofatto, Diego Brum, Luiz Gonzaga, Jr., Marcelo Zagonel de Oliveira, Mauricio Roberto Veronez
Publikováno v:
The Lancet Regional Health. Americas, Vol 6, Iss , Pp 100102- (2022)
Summary: Background: Brazil has faced two simultaneous problems related to respiratory health: forest fires and the high mortality rate due to COVID-19 pandemics. The Amazon rain forest is one of the Brazilian biomes that suffers the most with fires
Externí odkaz:
https://doaj.org/article/f1fb3a6cf8ad49349744cded44075273
Autor:
Clévia Rosset, Mariane da Cunha Jaeger, Eduardo Filippi-Chiela, Larissa Brussa Reis, Ivaine Taís Sauthier Sartor, Cristina Brinckmann Oliveira Netto, Caroline Brunetto de Farias, Rafael Roesler, Patricia Ashton-Prolla
Publikováno v:
Genetics and Molecular Biology, Vol 44, Iss 4 (2021)
Abstract Tuberous sclerosis complex (TSC) is an autosomal dominant cancer predisposition disorder caused by heterozygous mutations in TSC1 or TSC2 genes and characterized by mTORC1 hyperactivation. TSC-associated tumors develop after loss of heterozy
Externí odkaz:
https://doaj.org/article/fe7d672f066a416495abc777371618de
Autor:
Larissa Brussa Reis, Eduardo C. Filippi-Chiela, Patricia Ashton-Prolla, Fernanda Visioli, Clévia Rosset
Publikováno v:
Genetics and Molecular Biology, Vol 44, Iss 2 (2021)
Abstract Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder caused by germline mutations in TSC1 or TSC2 genes, which leads to the hyperactivation of the mTORC1 pathway, an important negative regulator of autophagy. This leads
Externí odkaz:
https://doaj.org/article/ffd9e85b2b68463aa67ec103834d3c64
Autor:
Camila Matzenbacher Bittar, Yasminne Marinho de Araújo Rocha, Igor Araujo Vieira, Clévia Rosset, Tiago Finger Andreis, Ivaine Tais Sauthier Sartor, Osvaldo Artigalás, Cristina B O Netto, Barbara Alemar, Gabriel S Macedo, Patricia Ashton-Prolla
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0251639 (2021)
Li-Fraumeni syndrome (LFS) is an autosomal dominant cancer predisposition syndrome caused by pathogenic germline variants in the TP53 gene, characterized by a predisposition to the development of a broad spectrum of tumors at an early age. The core t
Externí odkaz:
https://doaj.org/article/5faa01362f1d4910bee4c50e4ee2336c
Autor:
Cleandra Gregório, Clévia Rosset, Laura da Silva Alves, Cristina Brinkmann Oliveira Netto, Simone Marcia dos Santos Machado, Vivian Pierri Bersch, Alessandro Bersch Osvaldt, Patricia Ashton-Prolla
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
IntroductionIn this study, we describe for the first time a Neurofibromatosis type 1 patient with pancreas divisum, multiple periampullary tumors and germline pathogenic variants in NF1 and CFTR genes.Case reportA 62-year-old female NF1 patient prese
Externí odkaz:
https://doaj.org/article/36d62257304945cf99e5fa43149aba2f