Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Clémentine Krucker"'
Autor:
Claire Béraud, Nadege Bidan, Myriam Lassalle, Hervé Lang, Véronique Lindner, Clémentine Krucker, Julien Masliah-Planchon, Eric Potiron, Philippe Lluel, Thierry Massfelder, Yves Allory, Yolande Misseri
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDespite the significant advances in the management of advanced prostate cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in precision treatment, the development of preclinical models representing th
Externí odkaz:
https://doaj.org/article/b98cdf9241d943d58e20b5feeffc4c38
Autor:
Hervé Lang, Claire Béraud, Luc Cabel, Jacqueline Fontugne, Myriam Lassalle, Clémentine Krucker, Florent Dufour, Clarice S. Groeneveld, Victoria Dixon, Xiangyu Meng, Aurélie Kamoun, Elodie Chapeaublanc, Aurélien De Reynies, Xavier Gamé, Pascal Rischmann, Ivan Bieche, Julien Masliah-Planchon, Romane Beaurepere, Yves Allory, Véronique Lindner, Yolande Misseri, François Radvanyi, Philippe Lluel, Isabelle Bernard-Pierrot, Thierry Massfelder
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMuscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are
Externí odkaz:
https://doaj.org/article/530d7616638a4e26a742ecd5e89e062d
Autor:
Natacha Rochel, Clémentine Krucker, Laure Coutos-Thévenot, Judit Osz, Ruiyun Zhang, Elodie Guyon, Wayne Zita, Séverin Vanthong, Oscar Alba Hernandez, Maxime Bourguet, Kays Al Badawy, Florent Dufour, Carole Peluso-Iltis, Syrine Heckler-Beji, Annick Dejaegere, Aurélie Kamoun, Aurélien de Reyniès, Yann Neuzillet, Sandra Rebouissou, Claire Béraud, Hervé Lang, Thierry Massfelder, Yves Allory, Sarah Cianférani, Roland H. Stote, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Activation of the PPARγ/RXRα pathway in luminal bladder cancers has mainly been linked to PPARG gene amplifications and activating point mutations in RXRα. Here, the authors identify recurrent PPARγ mutations with similar effects and elucidate th
Externí odkaz:
https://doaj.org/article/5e44a383003c4ce0b87b4a701664d7c3
Autor:
Yann Neuzillet, Elodie Chapeaublanc, Clémentine Krucker, Leanne De Koning, Thierry Lebret, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background The insulin growth factor (IGF) pathway has been proposed as a potential therapeutic target in bladder cancer. We characterized the expression of components of the IGF pathway — insulin growth factor receptors (INSR, IGF1R, IGF2
Externí odkaz:
https://doaj.org/article/6166f90451174a048a406c55c1d81e6c
Autor:
Edith Borcoman, Philippe De La Rochere, Wilfrid Richer, Sophie Vacher, Walid Chemlali, Clémentine Krucker, Nanour Sirab, Francois Radvanyi, Yves Allory, Géraldine Pignot, Nicolas Barry de Longchamps, Diane Damotte, Didier Meseure, Christine Sedlik, Ivan Bieche, Eliane Piaggio
Publikováno v:
OncoImmunology, Vol 8, Iss 5 (2019)
Although immune checkpoint inhibitors have shown improvement in survival in comparison to chemotherapy in urothelial bladder cancer, many patients still fail to respond to these treatments and actual efforts are made to identify predictive factors of
Externí odkaz:
https://doaj.org/article/0db6fac15b164f528cf33ffba30b6ee8
Autor:
Anne Biton, Isabelle Bernard-Pierrot, Yinjun Lou, Clémentine Krucker, Elodie Chapeaublanc, Carlota Rubio-Pérez, Nuria López-Bigas, Aurélie Kamoun, Yann Neuzillet, Pierre Gestraud, Luca Grieco, Sandra Rebouissou, Aurélien de Reyniès, Simone Benhamou, Thierry Lebret, Jennifer Southgate, Emmanuel Barillot, Yves Allory, Andrei Zinovyev, François Radvanyi
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1235-1245 (2014)
Extracting relevant information from large-scale data offers unprecedented opportunities in cancerology. We applied independent component analysis (ICA) to bladder cancer transcriptome data sets and interpreted the components using gene enrichment an
Externí odkaz:
https://doaj.org/article/fc9494082fea48fdaec4ebd243c8bd7f
Autor:
Hélène Neyret-Kahn, Jacqueline Fontugne, Xiang Yu Meng, Clarice S. Groeneveld, Luc Cabel, Tao Ye, Elodie Guyon, Clémentine Krucker, Florent Dufour, Elodie Chapeaublanc, Audrey Rapinat, Daniel Jeffery, Laura Tanguy, Victoria Dixon, Yann Neuzillet, Thierry Lebret, David Gentien, Irwin Davidson, Yves Allory, Isabelle Bernard-Pierrot, François Radvanyi
Publikováno v:
Oncogene. 42:1524-1542
Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, presenting distinct molecular and clinical characteristics. However, how these dist
Autor:
Ming-Jun Shi, Jacqueline Fontugne, Aura Moreno-Vega, Xiang-Yu Meng, Clarice Groeneveld, Florent Dufour, Aurélie Kamoun, Sia Viborg Lindskrog, Luc Cabel, Clémentine Krucker, Audrey Rapinat, Claire Dunois-Larde, May-Linda Lepage, Elodie Chapeaublanc, Olivier Levrel, Victoria Dixon, Thierry Lebret, Anna Almeida, Aurélien De Reynies, Natacha Rochel, Lars Dyrskjøt, Yves Allory, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
European Urology
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
Background: Bladder cancer (BCa) is more common in men and presents differences in molecular subtypes based on sex. Fibroblast growth factor receptor 3 (FGFR3) mutations are enriched in the luminal papillary muscle-invasive BCa (MIBC) and non-MIBC su
Autor:
Stéphane Culine, Valentin Harter, Clémentine Krucker, Gwenaelle Gravis, Aude Fléchon, Christine Chevreau, Hakim Mahammedi, Brigitte Laguerre, Aline Guillot, Florence Joly, Jacqueline Fontugne, Yves Allory, Christian Pfister
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1742
Neoadjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy and pelvic lymph node dissection is the optimal treatment for patients with muscle-invasive bladder cancer. In recent years, the VESPER trial showed a statistically signifi
Autor:
Hélène Neyret-Kahn, Jacqueline Fontugne, Xiang Yu Meng, Clarice S. Groeneveld, Luc Cabel, Tao Ye, Elodie Guyon, Clémentine Krucker, Florent Dufour, Elodie Chapeaublanc, Audrey Rapinat, Daniel Jeffery, Yann Neuzillet, Thierry Lebret, David Gentien, Irwin Davidson, Yves Allory, Isabelle Bernard-Pierrot, François Radvanyi
Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, presenting distinct molecular and clinical characteristics. However, how these dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec82ae3d347ea4a257bfc8fef9789efc
https://doi.org/10.1101/2022.01.11.475197
https://doi.org/10.1101/2022.01.11.475197