Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Clément Thomas"'
Autor:
Andrea Michela Biolato, Liza Filali, Diogo Pereira Fernandes, Flora Moreau, Takouhie Mgrditchian, Céline Hoffmann, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The formation of a lytic immunological synapse (IS) is crucial for cytotoxic lymphocytes to accurately target and effectively eliminate malignant cells. While significant attention has been focused on the lymphocyte side of the IS, particularly its r
Externí odkaz:
https://doaj.org/article/40bc63f8a2e14f1180086ed51cbcecb9
Autor:
Guillaume Herpe, Clément Giraud, Clément Thomas, Jean‐Philippe Neau, Stéphane Velasco, Victor Dumas, Luc Pellerin, Carole Guillevin, Rémy Guillevin
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 6 (2023)
Background Predicting clinical outcome based on either the postprocedural recanalization score (modified treatment in cerebral infarction) or the initial National Institute of Health Stroke Scale (NIHSS) clinical score performed immediately after the
Externí odkaz:
https://doaj.org/article/8f4117d121664bc6a61ef5bab1ec9f24
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytotoxic lymphocytes (CLs), specifically cytotoxic T lymphocytes and natural killer cells, are indispensable guardians of the immune system and orchestrate the recognition and elimination of cancer cells. Upon encountering a cancer cell, CLs establi
Externí odkaz:
https://doaj.org/article/2ce692d133a94eb2bea516bfe5d57705
Autor:
Rodolphe Vallée, Jean-Noël Vallée, Carole Guillevin, Athéna Lallouette, Clément Thomas, Guillaume Rittano, Michel Wager, Rémy Guillevin, Alexandre Vallée
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTo investigate the contribution of machine learning decision tree models applied to perfusion and spectroscopy MRI for multiclass classification of lymphomas, glioblastomas, and metastases, and then to bring out the underlying key pathophys
Externí odkaz:
https://doaj.org/article/f4e74cdcec66455ab6dd201b50ea530b
Autor:
Takouhie Mgrditchian, Joshua Brown-Clay, Céline Hoffmann, Tanja Müller, Liza Filali, Elena Ockfen, Xianqing Mao, Flora Moreau, Carla Pou Casellas, Tony Kaoma, Michel Mittelbronn, Clément Thomas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The actin cytoskeleton plays a critical role in cancer cell invasion and metastasis; however, the coordination of its multiple functions remains unclear. Actin dynamics in the cytoplasm control the formation of invadopodia, which are membrane protrus
Externí odkaz:
https://doaj.org/article/c2b8619594984cbea893d4b0fc76ae51
Autor:
Guillaume Herpe, Julien Dambrine, Inès Bennis, Clément Thomas, Stéphane Velasco, Rémy Guillevin
Publikováno v:
AIMS Mathematics, Vol 6, Iss 1, Pp 938-951 (2021)
The analysis of Cerebral Angiographies are an essential tool for the assessment of the future of patients that underwent thrombolysis after a stroke event. Many semi-qualitative visual diagnostic scales have been developed for this purpose. Perfusion
Externí odkaz:
https://doaj.org/article/edc1bd67855e409b8c2e89421c6db9e1
Publikováno v:
PLoS Biology, Vol 19, Iss 8 (2021)
How cytotoxic lymphocytes are protected against their own weapons during close combat with diseased target cells is an important and long-standing question in immunology. A study in this issue provides new insights into the mechanisms by which natura
Externí odkaz:
https://doaj.org/article/cb7546c9a52e438a9d79511fe98c706a
Autor:
Hannah Wurzer, Liza Filali, Céline Hoffmann, Max Krecke, Andrea Michela Biolato, Jérôme Mastio, Sigrid De Wilde, Jean Hugues François, Anne Largeot, Guy Berchem, Jérôme Paggetti, Etienne Moussay, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term. For effective lys
Externí odkaz:
https://doaj.org/article/6022f7d32a004eda80782d5d6124ada7
Autor:
Jérôme Mastio, Mezida B. Saeed, Hannah Wurzer, Max Krecke, Lisa S. Westerberg, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Congenital defects of the immune system called primary immunodeficiency disorders (PID) describe a group of diseases characterized by a decrease, an absence, or a malfunction of at least one part of the immune system. As a result, PID patients are mo
Externí odkaz:
https://doaj.org/article/99592bf8e5324e7f844b48103c560886
Autor:
Céline Hoffmann, Xianqing Mao, Joshua Brown-Clay, Flora Moreau, Antoun Al Absi, Hannah Wurzer, Barbara Sousa, Fernando Schmitt, Guy Berchem, Bassam Janji, Clément Thomas
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion. Here, we show
Externí odkaz:
https://doaj.org/article/9aa369442f8843179906f34893c25651