Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Clément Regnault"'
Autor:
Federica Giordani, Daniel Paape, Isabel M Vincent, Andrew W Pountain, Fernando Fernández-Cortés, Eva Rico, Ning Zhang, Liam J Morrison, Yvonne Freund, Michael J Witty, Rosemary Peter, Darren Y Edwards, Jonathan M Wilkes, Justin J J van der Hooft, Clément Regnault, Kevin D Read, David Horn, Mark C Field, Michael P Barrett
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008932 (2020)
Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promis
Externí odkaz:
https://doaj.org/article/a5d1aac4a0fd47b29679ea476bd015f8
Autor:
Eva Doleželová, Michaela Kunzová, Mario Dejung, Michal Levin, Brian Panicucci, Clément Regnault, Christian J Janzen, Michael P Barrett, Falk Butter, Alena Zíková
Publikováno v:
PLoS Biology, Vol 18, Iss 6, p e3000741 (2020)
Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life cycle because the insect stage utilizes a cost-effective oxidative phosphorylation (OxPhos) to generate ATP, while bloodstream cells switch to aerobic glycolysi
Externí odkaz:
https://doaj.org/article/a36779139e0b4aaaba1556403084e023
Autor:
Andrew W Pountain, Stefan K Weidt, Clément Regnault, Paul A Bates, Anne M Donachie, Nicholas J Dickens, Michael P Barrett
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007052 (2019)
Amphotericin B is an increasingly important tool in efforts to reduce the global disease burden posed by Leishmania parasites. With few other chemotherapeutic options available for the treatment of leishmaniasis, the potential for emergent resistance
Externí odkaz:
https://doaj.org/article/02c7db962fdf4558835e9797401ea3bc
Autor:
Hector M. Diaz-Albiter, Clément Regnault, Edubiel A. Alpizar-Sosa, Dagmara McGuinness, Michael Barrett, Rod J. Dillon
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Background: The leishmaniases are neglected diseases that affect some of the most vulnerable populations in the tropical and sub-tropical world. The parasites are transmitted by sand flies and novel strategies to control this neglected vector-borne d
Externí odkaz:
https://doaj.org/article/2dfdb128dd154b15986b9fbd761335bf
Autor:
Jessica M. Bryant, Clément Regnault, Christine Scheidig-Benatar, Sebastian Baumgarten, Julien Guizetti, Artur Scherf
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Plasmodium falciparum relies on monoallelic expression of 1 of 60 var virulence genes for antigenic variation and host immune evasion. Each var gene contains a conserved intron which has been implicated in previous studies in both activation
Externí odkaz:
https://doaj.org/article/91d89e87606c4bb78714e1eb9743529d
Autor:
Michael P. Barrett, Jonathan M. Cooper, Clément Regnault, Stefan H. Holm, Jason P. Beech, Jonas O. Tegenfeldt, Axel Hochstetter
Publikováno v:
Pathogens, Vol 6, Iss 4, p 47 (2017)
African trypanosomes are responsible for significant levels of disease in both humans and animals. The protozoan parasites are free-living flagellates, usually transmitted by arthropod vectors, including the tsetse fly. In the mammalian host they liv
Externí odkaz:
https://doaj.org/article/e4af60e7dd2c429b8da02036ad7db7cd
Autor:
Matthew Berriman, J. Alexandra Rowe, Simon J. Draper, Michael P. Barrett, Sarah E. Silk, Geetha Sankaranarayanan, Wiebke Nahrendorf, Philip J Spence, Diana Munoz Sandoval, Mandy Sanders, Angela M. Minassian, Clément Regnault, Alasdair Ivens, Ruth O. Payne, N Venkatraman, Adam J. Reid, Magda E. Lotkowska, Áine O'Toole, Kathryn H. Milne, Nick J. Edwards, Adrian V. S. Hill
Publikováno v:
eLife, Vol 10 (2021)
Milne, K, Ivens, A, Reid, A J, Lotkowska, M E, O'Toole, Á, Sankaranarayanan, G, Munoz Sandoval, D, Nahrendorf, W, Regnault, C, Edwards, N J, Silk, S E, Payne, R O, Minassian, A M, Venkatraman, N, Sanders, M, Hill, A V S, Barrett, M P, Berriman, M, Draper, S J, Rowe, A J & Spence, P J 2021, ' Mapping immune variation and var gene switching in naïve hosts infected with Plasmodium falciparum ', eLIFE, vol. 10, e62800 . https://doi.org/10.7554/eLife.62800
Milne, K, Ivens, A, Reid, A J, Lotkowska, M E, O'Toole, Á, Sankaranarayanan, G, Munoz Sandoval, D, Nahrendorf, W, Regnault, C, Edwards, N J, Silk, S E, Payne, R O, Minassian, A M, Venkatraman, N, Sanders, M, Hill, A V S, Barrett, M P, Berriman, M, Draper, S J, Rowe, A J & Spence, P J 2021, ' Mapping immune variation and var gene switching in naïve hosts infected with Plasmodium falciparum ', eLIFE, vol. 10, e62800 . https://doi.org/10.7554/eLife.62800
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, ask
Autor:
Adrian V. S. Hill, Simon J. Draper, Matthew Berriman, Ruth O. Payne, N Venkatraman, J. Alexandra Rowe, Clément Regnault, Michael P. Barrett, Nick J. Edwards, Philip J Spence, Geetha Sankaranarayanan, Sarah E. Silk, Mandy Sanders, Angela M. Minassian, Diana Munoz Sandoval, Kathryn H. Milne, Magda E. Lotkowska, Áine O'Toole, Alasdair Ivens, Wiebke Nahrendorf, Adam J. Reid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03827e696dd9dfb2b3297deaa5b825d3
https://doi.org/10.7554/elife.62800.sa2
https://doi.org/10.7554/elife.62800.sa2
Autor:
Eva Rico, Andrew W. Pountain, Isabel M. Vincent, Michael J. Witty, Michael P. Barrett, Fernando Fernandez-Cortes, Ning Zhang, Mark C. Field, David Horn, Jonathan M. Wilkes, Justin J. J. van der Hooft, Yvonne Freund, Darren Y. Edwards, Daniel Paape, Liam J. Morrison, Rosemary Peter, Clément Regnault, Federica Giordani, Kevin D. Read
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008932 (2020)
PLoS Pathogens
PLoS Pathogens, 16(11)
PLoS Pathogens 16 (2020) 11
Giordani, F, Paape, D, Vincent, I M, Pountain, A W, Fernandez-Cortes, F, Rico, E, Zhang, N, Morrison, L, Freund, Y, Witty, M J, Peter, R, Edwards, D, Wilkes, J, van der Hooft, J J J, Regnault, C, Read, K D, Horn, D, Field, M C & Barrett, M P 2020, ' Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs ', PLoS Pathogens, vol. 16, no. 11, e1008932 . https://doi.org/10.1371/journal.ppat.1008932
PLoS Pathogens
PLoS Pathogens, 16(11)
PLoS Pathogens 16 (2020) 11
Giordani, F, Paape, D, Vincent, I M, Pountain, A W, Fernandez-Cortes, F, Rico, E, Zhang, N, Morrison, L, Freund, Y, Witty, M J, Peter, R, Edwards, D, Wilkes, J, van der Hooft, J J J, Regnault, C, Read, K D, Horn, D, Field, M C & Barrett, M P 2020, ' Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs ', PLoS Pathogens, vol. 16, no. 11, e1008932 . https://doi.org/10.1371/journal.ppat.1008932
Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promis
Autor:
Sarah E. Silk, Adam J. Reid, Michael P. Barrett, Wiebke Nahrendorf, Philip J Spence, Diana Munoz Sandoval, Kathryn H. Milne, Simon J. Draper, Nick J. Edwards, Adrian V. S. Hill, Ruth O. Payne, Clément Regnault, Magda E. Lotkowska, J. Alexandra Rowe, Alasdair Ivens, Áine O'Toole, Matthew Berriman, Mandy Sanders, Angela M. Minassian, N Venkatraman, Geetha Sankaranarayanan
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, ask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb77ec72feb2ccdc5f3e18fd0efcd0c5
https://doi.org/10.1101/2020.09.04.20188144
https://doi.org/10.1101/2020.09.04.20188144