Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Clément Nguyen"'
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113032- (2023)
Summary: Mitochondrial dysfunction is a critical process in renal epithelial cells upon kidney injury. While its implication in kidney disease progression is established, the mechanisms modulating it remain unclear. Here, we describe the role of Lipo
Externí odkaz:
https://doaj.org/article/1965e843d698442e91e0bdf7f60ba2dc
Autor:
Camille Cohen, Océane Le Goff, Frédéric Soysouvanh, Florence Vasseur, Marine Tanou, Clément Nguyen, Lucile Amrouche, Julien Le Guen, Oriana Saltel‐Fulero, Tanguy Meunier, Thao Nguyen‐Khoa, Marion Rabant, Dominique Nochy, Christophe Legendre, Gérard Friedlander, Bennett G Childs, Daren J Baker, Bertrand Knebelmann, Dany Anglicheau, Fabien Milliat, Fabiola Terzi
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp n/a-n/a (2021)
Abstract The mechanisms underlying the development of glomerular lesions during aging are largely unknown. It has been suggested that senescence might play a role, but the pathophysiological link between senescence and lesion development remains unex
Externí odkaz:
https://doaj.org/article/eff346c772ac4a2782e8d2599fcc5044
Autor:
Khalil El Karoui, Amandine Viau, Olivier Dellis, Alessia Bagattin, Clément Nguyen, William Baron, Martine Burtin, Mélanie Broueilh, Laurence Heidet, Géraldine Mollet, Anne Druilhe, Corinne Antignac, Bertrand Knebelmann, Gérard Friedlander, Frank Bienaimé, Morgan Gallazzini, Fabiola Terzi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Proteinuria promotes chronic kidney disease progression. Karoui et al. show that proteinuria stimulates overexpression of iron transporting protein lipocalin-2 via Ca2+release-induced ER stress, which leads to tubular apoptosis, and that inhibition o
Externí odkaz:
https://doaj.org/article/84d6beb4c2bc4aa9bafacf3ebe31468b
Autor:
Aurélie Phelep, Denise Laouari, Kapil Bharti, Martine Burtin, Salvina Tammaccaro, Serge Garbay, Clément Nguyen, Florence Vasseur, Thomas Blanc, Sophie Berissi, Francina Langa-Vives, Evelyne Fischer, Anne Druilhe, Heinz Arnheiter, Gerard Friedlander, Marco Pontoglio, Fabiola Terzi
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007093 (2017)
Congenital nephron number varies widely in the human population and individuals with low nephron number are at risk of developing hypertension and chronic kidney disease. The development of the kidney occurs via an orchestrated morphogenetic process
Externí odkaz:
https://doaj.org/article/6752b6f74c8d47d5b382dee7a6c03339
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
ITER Central Solenoid Precompression Test Mock-up – Validation phase to prepare the assembly on-site
Autor:
Cyril Brun, Clément Nguyen, Patrick Decool, Antoine Jonas, Thierry Schild, Carl Cormany, Travis Reagan, David Vandergriff, Kevin Freudenberg
Publikováno v:
Fusion Engineering and Design. 194:113705
Autor:
Florence Vasseur, Fabien Milliat, Dominique Nochy, Daren J Baker, Marine Tanou, Christophe Legendre, Camille Cohen, Clément Nguyen, Bennett G. Childs, Tanguy Meunier, Julien Le Guen, Frédéric Soysouvanh, Fabiola Terzi, Bertrand Knebelmann, Gérard Friedlander, Océane Le Goff, Thao Nguyen-Khoa, Marion Rabant, Oriana Saltel-Fulero, Lucile Amrouche, Dany Anglicheau
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine
The mechanisms underlying the development of glomerular lesions during aging are largely unknown. It has been suggested that senescence might play a role, but the pathophysiological link between senescence and lesion development remains unexplained.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Frédéric Soysouvanh, Fabiola Terzi, Legoff Oceanc, Tanguy Meunier, Camille Cohen, Marine Tanou, Lucile Amrouche, Dominique Nochy, Marion Rabant, Fabien Milliat, Clément Nguyen, Florence Vasseur, Dany Anglicheau, Christophe Legendre
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims In age-related chronic kidney disease (CKD), the most frequent histological lesion observed is glomerulosclerosis. The molecular mechanisms involved in this deterioration process are unclear, but cellular senescence might play a r
Autor:
Lucie Yammine, Mohamad Zaidan, Marco Pontoglio, Serena Germano, Marie-Claire Gubler, Gérard Friedlander, Serge Garbay, Morgan Gallazzini, Clément Nguyen, Jitao David Zhang, Thomas Blanc, Laura Badi, Pauline Barre, Fabiola Terzi, Martine Burtin, Florence Vasseur
Publikováno v:
JCI Insight
The loss of functional nephrons after kidney injury triggers the compensatory growth of the remaining ones to allow functional adaptation. However, in some cases, these compensatory events activate signaling pathways that lead to pathological alterat