Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Clément Judes"'
Autor:
Jean-Jacques Helwig, Catherine Muller, Buer Zhu, Clément Judes, J. Geisert, Thierry Massfelder, Umberto Simeoni
Publikováno v:
Pediatric Research. 42:550-555
Studies were performed on isolated perfused kidneys (IPK) from postnatal developing rabbits to ask 1) whether the high renal vascular resistance (RVR) at birth involves intrinsic renal mechanisms, 2) whether nitric oxide (NO) release is involved in t
Autor:
Thierry Massfelder, Umberto Simeoni, Jean-Jacques Helwig, G. Allen Nickols, Michael Steinhausen, Clément Judes, Karlhans Endlich, Christian Saussine
Publikováno v:
Journal of Bone and Mineral Metabolism. 12:S199-S206
Parathyroid hormone (PTH)-related protein (PTHrP) is the main factor responsible for the syndrome of humoral hypercalcemia of malignancy. In addition, PTHrP is produced by a multitude of normal as well as malignant cells and exerts both classic PTH-l
Autor:
Thierry Massfelder, Karlhans Endlich, Clément Judes, N E Soifer, Andrew F. Stewart, Jean-Jacques Helwig
Publikováno v:
Kidney international. 50(5)
Parathyroid hormone-related protein detection and interaction with NO and cyclic AMP in the renovascular system. The presence of parathyroid hormone-related protein (PTHrP) in human kidney vasculature and the signal transduction pathways stimulated d
Autor:
Christian Saussine, Thierry Massfelder, Clément Judes, Umberto Simeoni, J. Geisert, Jean-Jacques Helwig
Publikováno v:
Clinical science (London, England : 1979). 86(3)
1. The present study was designed to explore the role of NO derived from l-arginine in the vasodilatory response to synthetic human parathyroid hormone-related peptide-(1–34) in the isolated rabbit kidney perfused in the presence of indomethacin (1
Autor:
Christian Saussine, Clément Judes, Frederique Parnin, Umberto Simeoni, Thierry Massfelder, Jean-Jacques Helwig
Publikováno v:
Kidney international. 44(4)
Renin stimulating properties of parathyroid hormone-related peptide in the isolated perfused rat kidney. Previous studies showed that PTHrP exhibits renal vasodilating, arteriolar cAMP stimulating and receptor binding properties. The present experime
Autor:
Clément Judes, Umberto Simeoni, Jean-Jacques Helwig, T. Hannedouche, Christian Saussine, Thierry Massfelder, M J Musso
Publikováno v:
Clinical science (London, England : 1979). 84(1)
1. We have previously reported that pharmacological concentrations (125 nmol/l) of parathyroid hormone may stimulate renin release in the stable recirculating and non-filtering isolated rat kidney. 2. In the present study we have attempted to extend
Autor:
Umberto Simeoni, Thierry Massfelder, Bertin Enanga, Jean-Jacques Helwig, Clément Judes, Christian Saussine
Publikováno v:
Life sciences. 53(11)
Studies were conducted to test whether parathyroid hormone-related protein (PTHrP) is able to stimulate adenylate cyclase activity in isolated rabbit glomeruli. Maximal stimulations were reached at 10 −7 M of human PTHrP-(1–34) or rat PTH-(1–34
Publikováno v:
European Journal of Pharmacology. 140:247-257
It has been shown previously that secondary structural changes of bPTH-(1-34) (synthetic amino-terminal (1–34) fragment of bovine parathyroid hormone), obtained by oxidation of the methionines 8 and 18, abolished its hypotensive but not its hyperca
Publikováno v:
Neonatology. 53:113-120
To examine the effect of prostaglandins on adenylate cyclase during the postnatal maturation of kidney, the prostaglandin E2 (PGE2) responsiveness of adenylate cyclase in the absence and presence of exogenous GTP was investigated in glomeruli and tub
Publikováno v:
European Journal of Pharmacology. 174:139-151
The hypercalcemia caused by malignancy factor, also called parathyroid hormone-related protein (PTHrP), exhibits most of the biological activities of parathyroid hormone (PTH) in kidney and bone. On the basis of the well-documented vascular action of