Zobrazeno 1 - 5
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pro vyhledávání: '"Clément Bechtler"'
Publikováno v:
CHIMIA, Vol 75, Iss 6, Pp 495-499 (2021)
Among the many molecular entities suitable for therapeutic use, peptides have emerged as a particularly attractive option for academic drug discovery and development. Their modular structure and extendibility, the availability of powerful and afforda
Externí odkaz:
https://doaj.org/article/e4722846a5e24cce8e8b18bdc5ff967a
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 5, Pp n/a-n/a (2022)
Abstract Background The factor XIII (FXIII)‐B subunit has a critical function as a carrier protein to stabilize FXIII‐A in plasma and supply it to its main substrate, fibrinogen. However, the function of the excess free FXIII‐B circulating in p
Externí odkaz:
https://doaj.org/article/a3ea7e83cc12424f8414b1c5a0dc45e1
Autor:
Clément Bechtler, Ouliana Barneoud‐Rousset, Lijuan Pang, Kea Martin, Katrin F. König, Pascal Hänggi, Nick Pearson, Daniel Ricklin
Publikováno v:
Chemical Biology & Drug Design.
Autor:
Clément Bechtler, Sophia Koutsogiannaki, Ekaterina Umnyakova, Amal Hamid, Avneesh Gautam, Yiannis Sarigiannis, Richard B. Pouw, Christina Lamers, Said Rabbani, Christoph Q. Schmidt, John D. Lambris, Daniel Ricklin
Publikováno v:
Acta biomaterialia. 155
The use of biomaterials in modern medicine has enabled advanced drug delivery strategies and led to reduced morbidity and mortality in a variety of interventions such as transplantation or hemodialysis. However, immune-mediated reactions still presen
Autor:
Christina Lamers, Clément Bechtler
Publikováno v:
RSC Medicinal Chemistry
Peptides are a growing therapeutic class due to their unique spatial characteristics that can target traditionally “undruggable” protein–protein interactions and surfaces. Despite their advantages, peptides must overcome several key shortcoming