Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Clémence Thomas"'
Autor:
Anne-Pierre Morel, George W Hinkal, Clémence Thomas, Frédérique Fauvet, Stéphanie Courtois-Cox, Anne Wierinckx, Mojgan Devouassoux-Shisheboran, Isabelle Treilleux, Agnès Tissier, Baptiste Gras, Julie Pourchet, Isabelle Puisieux, Gareth J Browne, Douglas B Spicer, Joël Lachuer, Stéphane Ansieau, Alain Puisieux
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002723 (2012)
The epithelial-mesenchymal transition (EMT) is an embryonic transdifferentiation process consisting of conversion of polarized epithelial cells to motile mesenchymal ones. EMT-inducing transcription factors are aberrantly expressed in multiple tumor
Externí odkaz:
https://doaj.org/article/cea742889eda4b7e8c8e6148940ce073
Autor:
Anne-Pierre Morel, Marjory Lièvre, Clémence Thomas, George Hinkal, Stéphane Ansieau, Alain Puisieux
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2888 (2008)
Recently, two novel concepts have emerged in cancer biology: the role of so-called "cancer stem cells" in tumor initiation, and the involvement of an epithelial-mesenchymal transition (EMT) in the metastatic dissemination of epithelial cancer cells.
Externí odkaz:
https://doaj.org/article/c33f7ae14e62445289cf95511a9e7efb
Autor:
Philippe Clézardin, Marie Brevet, Antoine E. Karnoub, Géraldine Aimond, Clémence Thomas, Floriane Pez, Edith Bonnelye, Martine Croset, Casina Kan, Paola Di Mauro, Laura Ferreras, Caroline Reynaud
Supplementary figure legends from S1 to S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506b681f51e3e63df29d3c1cd4edea61
https://doi.org/10.1158/0008-5472.22411913.v1
https://doi.org/10.1158/0008-5472.22411913.v1
Autor:
Philippe Clézardin, Marie Brevet, Antoine E. Karnoub, Géraldine Aimond, Clémence Thomas, Floriane Pez, Edith Bonnelye, Martine Croset, Casina Kan, Paola Di Mauro, Laura Ferreras, Caroline Reynaud
Supplementary Table S1. Primer pairs used for quantitative real-time PCR analysis. Supplementary Table S2. Summary of the gene expression datasets used for meta-analysis. Supplementary Table S3. Expression levels of LOX-like mRNAs in Hct116 cells tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cb0f506b1611ac8ebf2bea535cb7aa
https://doi.org/10.1158/0008-5472.22411907.v1
https://doi.org/10.1158/0008-5472.22411907.v1
Autor:
Philippe Clézardin, Marie Brevet, Antoine E. Karnoub, Géraldine Aimond, Clémence Thomas, Floriane Pez, Edith Bonnelye, Martine Croset, Casina Kan, Paola Di Mauro, Laura Ferreras, Caroline Reynaud
Lysyl oxidase (LOX) is a secreted copper-dependent amine oxidase whose primary function is to drive collagen crosslinking and extracellular matrix stiffness. LOX in colorectal cancer synergizes with hypoxia-inducible factor-1 (HIF-1) to promote tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa6ac9faf7030fa3eb06539061a20c7
https://doi.org/10.1158/0008-5472.c.6508325.v1
https://doi.org/10.1158/0008-5472.c.6508325.v1
Autor:
Philippe Clézardin, Marie Brevet, Antoine E. Karnoub, Géraldine Aimond, Clémence Thomas, Floriane Pez, Edith Bonnelye, Martine Croset, Casina Kan, Paola Di Mauro, Laura Ferreras, Caroline Reynaud
Figure S1: LOX expression and clinical outcomes. Figure S2:The LOX inhibitor βAPN inhibits osteolytic lesion formation in vivo. Figure S3: Measurement of LOX enzymatic activity. Figure S4: Correlation analysis of the expression intensity of LOX and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed28ac88e4401f5ca74264c0790f9bf
https://doi.org/10.1158/0008-5472.22411910.v1
https://doi.org/10.1158/0008-5472.22411910.v1
Autor:
Clémence Thomas, Utkan Demirci, Joseph A. Khoory, Antoine E. Karnoub, Ionita Ghiran, Huseyin Cumhur Tekin, Savas Tasoglu
Publikováno v:
Advanced Materials. 27:3901-3908
A simple, yet powerful magnetic-levitation-based device is reported for real-time, label-free separation, as well as high-resolution monitoring of cell populations based on their unique magnetic and density signatures. This method allows a wide varie
Autor:
Marie Brevet, Casina W.S. Kan, Antoine E. Karnoub, Laura Ferreras, Floriane Pez, Edith Bonnelye, Martine Croset, Paola Di Mauro, Clémence Thomas, Caroline Reynaud, Géraldine Aimond, Philippe Clézardin
Publikováno v:
Cancer Research
Cancer Research, 2017, 77 (2), pp.268-278. ⟨10.1158/0008-5472.CAN-15-2621⟩
Cancer Research, American Association for Cancer Research, 2017, 77 (2), pp.268-278. ⟨10.1158/0008-5472.CAN-15-2621⟩
Cancer Research, 2017, 77 (2), pp.268-278. ⟨10.1158/0008-5472.CAN-15-2621⟩
Cancer Research, American Association for Cancer Research, 2017, 77 (2), pp.268-278. ⟨10.1158/0008-5472.CAN-15-2621⟩
Lysyl oxidase (LOX) is a secreted copper-dependent amine oxidase whose primary function is to drive collagen crosslinking and extracellular matrix stiffness. LOX in colorectal cancer synergizes with hypoxia-inducible factor-1 (HIF-1) to promote tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979feea5266c9b9550d3368a22ec7da1
https://hal.science/hal-03380388/document
https://hal.science/hal-03380388/document
Publikováno v:
Cell Cycle. 7:3659-3663
Metastasis is the main cause of death by cancer. Hence, establishing predictive markers constitutes a major clinical objective. The capacity for a tumor cell to migrate and survive from a primary tumor is often described as the ultimate step of Darwi
Autor:
Frédérique Fauvet, Agnès Doreau, Thibault Voeltzel, Abdelkader Selmi, Claude Caron de Fromentel, Benjamin Pierre Bouchet, Stéphane Ansieau, Alain Puisieux, Roberta Maestro, Claudio Doglioni, Clémence Thomas, Isabelle Puisieux, Sara Piccinin, Jérémy Bastid, Anne Pierre Morel, Sandrine Valsesia-Wittmann
Publikováno v:
Cancer Cell. 14:79-89
SummaryTwist1 and Twist2 are major regulators of embryogenesis. Twist1 has been shown to favor the metastatic dissemination of cancer cells through its ability to induce an epithelial-mesenchymal transition (EMT). Here, we show that a large fraction