Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Clémence Jacquemin"'
1
Akademický článek
A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity
Autor: Laure Perrin-Cocon, Pierre-Olivier Vidalain, Clémence Jacquemin, Anne Aublin-Gex, Keedrian Olmstead, Baptiste Panthu, Gilles Jeans Philippe Rautureau, Patrice André, Piotr Nyczka, Marc-Thorsten Hütt, Nivea Amoedo, Rodrigue Rossignol, Fabian Volker Filipp, Vincent Lotteau, Olivier Diaz
Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Many cancers fuel their rapid growth by replacing glucokinase with its higher affinity isoenzyme, hexokinase 2 (HK2), making HK2 an attractive drug target. In this study, Perrin-Cocon and Vidalain et al. use CRISPR/Cas-9 gene editing to reverse this
Externí odkaz: https://doaj.org/article/a519b0af2fba49868394944910f843d0
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2
Akademický článek
The current landscape of coronavirus-host protein–protein interactions
Autor: Laure Perrin-Cocon, Olivier Diaz, Clémence Jacquemin, Valentine Barthel, Eva Ogire, Christophe Ramière, Patrice André, Vincent Lotteau, Pierre-Olivier Vidalain
Publikováno v: Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds of thousands of deaths. Other coronaviruses are causing epizootic representing a significant
Externí odkaz: https://doaj.org/article/d2c409fff17147a89746b9beca0c2926
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3
Akademický článek
Domain 2 of Hepatitis C Virus Protein NS5A Activates Glucokinase and Induces Lipogenesis in Hepatocytes
Autor: Laure Perrin-Cocon, Cindy Kundlacz, Clémence Jacquemin, Xavier Hanoulle, Anne Aublin-Gex, Marianne Figl, Jeremy Manteca, Patrice André, Pierre-Olivier Vidalain, Vincent Lotteau, Olivier Diaz
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 2, p 919 (2022)
Hepatitis C virus (HCV) relies on cellular lipid metabolism for its replication, and actively modulates lipogenesis and lipid trafficking in infected hepatocytes. This translates into an intracellular accumulation of triglycerides leading to liver st
Externí odkaz: https://doaj.org/article/b441152eacc446fab2beaa32b55e1d80
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4
Akademický článek
A Bioluminescent 3CLPro Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors
Autor: Cyrille Mathieu, Franck Touret, Clémence Jacquemin, Yves L. Janin, Antoine Nougairède, Manon Brailly, Magalie Mazelier, Didier Décimo, Virginie Vasseur, Aymeric Hans, José-Carlos Valle-Casuso, Xavier de Lamballerie, Branka Horvat, Patrice André, Mustapha Si-Tahar, Vincent Lotteau, Pierre-Olivier Vidalain
Publikováno v: Viruses, Vol 13, Iss 9, p 1814 (2021)
Our therapeutic arsenal against viruses is very limited and the current pandemic of SARS-CoV-2 highlights the critical need for effective antivirals against emerging coronaviruses. Cellular assays allowing a precise quantification of viral replicatio
Externí odkaz: https://doaj.org/article/1a9317cb22094504984f528f143240ea
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5
A Bioluminescent 3CL
Autor: Cyrille, Mathieu, Franck, Touret, Clémence, Jacquemin, Yves L, Janin, Antoine, Nougairède, Manon, Brailly, Magalie, Mazelier, Didier, Décimo, Virginie, Vasseur, Aymeric, Hans, José-Carlos, Valle-Casuso, Xavier, de Lamballerie, Branka, Horvat, Patrice, André, Mustapha, Si-Tahar, Vincent, Lotteau, Pierre-Olivier, Vidalain
Publikováno v: Viruses
Our therapeutic arsenal against viruses is very limited and the current pandemic of SARS-CoV-2 highlights the critical need for effective antivirals against emerging coronaviruses. Cellular assays allowing a precise quantification of viral replicatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::569126f6468919762d95b84f68ab0fcf
https://pubmed.ncbi.nlm.nih.gov/34578395
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6
A Bioluminescent 3CLPro Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors
Autor: Xavier de Lamballerie, Manon Brailly, Yves L. Janin, Aymeric Hans, José-Carlos Valle-Casuso, Vincent Lotteau, Franck Touret, Mustapha Si-Tahar, Magalie Mazelier, Virginie Vasseur, Patrice Andre, Clémence Jacquemin, Pierre-Olivier Vidalain, Didier Decimo, Cyrille Mathieu, Branka Horvat, Antoine Nougairède
Publikováno v: Viruses
Viruses, MDPI, 2021, 13 (9), pp.1814. ⟨10.3390/v13091814⟩
Viruses, 2021, 13 (9), pp.1814. ⟨10.3390/v13091814⟩
Volume 13
Issue 9
Viruses, Vol 13, Iss 1814, p 1814 (2021)
International audience; Our therapeutic arsenal against viruses is very limited and the current pandemic of SARS-CoV-2 highlights the critical need for effective antivirals against emerging coronaviruses. Cellular assays allowing a precise quantifica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d76edd2f091c6a68664977010927cda
https://hal.archives-ouvertes.fr/hal-03357247
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8
Box C/D snoRNPs: solid-state NMR fingerprint of an early-stage 50 kDa assembly intermediate
Autor: Marie-Eve Chagot, Carole Gardiennet, Marc Quinternet, Xavier Manival, Clémence Jacquemin
Publikováno v: Biomolecular NMR Assignments
Biomolecular NMR Assignments, 2020, 14 (1), pp.131-140. ⟨10.1007/s12104-020-09933-y⟩
Biomolecular NMR Assignments, Springer, 2020, 14 (1), pp.131-140. ⟨10.1007/s12104-020-09933-y⟩
International audience; Many cellular functions rely on stable protein-only or protein-RNA complexes. Deciphering their assembly mechanism is a key question in cell biology. We here focus on box C/D small nucleolar ribonucleoproteins involved in ribo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826211538a84da91d5a9c1893d2a2aa0
https://pubmed.ncbi.nlm.nih.gov/32030621
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