Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Clélia, Coutzac"'
Autor:
Clélia Coutzac, Jean-Mehdi Jouniaux, Angelo Paci, Julien Schmidt, Domenico Mallardo, Atmane Seck, Vahe Asvatourian, Lydie Cassard, Patrick Saulnier, Ludovic Lacroix, Paul-Louis Woerther, Aurore Vozy, Marie Naigeon, Laetitia Nebot-Bral, Mélanie Desbois, Ester Simeone, Christine Mateus, Lisa Boselli, Jonathan Grivel, Emilie Soularue, Patricia Lepage, Franck Carbonnel, Paolo Antonio Ascierto, Caroline Robert, Nathalie Chaput
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The gut microbiota has been reported to regulate the efficacy of cancer therapy. Here, the authors show that short-chain fatty acids, which are generated through bacterial fermentation, increases immune tolerance leading to resistance to anti-CTLA-4
Externí odkaz:
https://doaj.org/article/1117fcdf2fd44e30b8bbaa1e829d3ecf
Autor:
Philippe A. Cassier, Clémentine Peyramaure, Valery Attignon, Lauriane Eberst, Camille Pacaud, Sandrine Boyault, Françoise Desseigne, Mathieu Sarabi, Pierre Guibert, Pauline Rochefort, Nathalie Marques, Michel Rivoire, Aurélien Dupré, Patrice Peyrat, Catherine Terret, Isabelle Ray-Coquard, Clélia Coutzac, David Pérol, Jean-Yves Blay, Olivier Trédan, Christelle de la Fouchardière
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101266- (2022)
Background: Chemotherapy, anti-HER2 and PD-1 antibodies are standard treatments but only a minority of patients derive long-term benefit from these agents. Methods: In this report we describe the mutational landscape and outcome of patients with gast
Externí odkaz:
https://doaj.org/article/af51f8a698dc4ce7a25e81ac463e3700
Autor:
Romain Varnier, Thibaut Garrivier, Emilie Hafliger, Aymeric Favre, Clélia Coutzac, Clément Spire, Pauline Rochefort, Matthieu Sarabi, Françoise Desseigne, Pierre Guibert, Anne Cattey-Javouhey, Pamela Funk-Debleds, Charles Mastier, Adrien Buisson, David Pérol, Oliver Trédan, Jean-Yves Blay, Jean-Marc Phelip, Christelle de la Fouchardiere
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Immune checkpoint inhibitors (ICI) have been developed in gastric adenocarcinomas and approved in first-line metastatic setting (in combination with chemotherapy) as well as in pretreated patients. Microsatellite instability-high (MSI-H) tumors are p
Externí odkaz:
https://doaj.org/article/2224c227c53b4b719b18694921a201c0
Autor:
Clélia Coutzac, Paméla Funk-Debleds, Anne Cattey-Javouhey, Françoise Desseigne, Pierre Guibert, Pauline Marolleau, Pauline Rochefort, Christelle de la Fouchardière
Publikováno v:
Bulletin du Cancer. 110:552-559
Gastric and esophageal adenocarcinomas represent a biologically heterogeneous disease. The identification, in early eighties, of human epidermal growth factor receptor 2 (HER2) overexpression, being present in 12 to 20% of the cases, marked a major m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043494fbf690daadd22d78e995cf4cb0
https://doi.org/10.1016/j.bulcan.2022.08.013
https://doi.org/10.1016/j.bulcan.2022.08.013
Autor:
Vahé Asvatourian, Clélia Coutzac, Nathalie Chaput, Caroline Robert, Stefan Michiels, Emilie Lanoy
Publikováno v:
BMC Medical Research Methodology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Recently, the intervention calculus when the DAG is absent (IDA) method was developed to estimate lower bounds of causal effects from observational high-dimensional data. Originally it was introduced to assess the effect of baseli
Externí odkaz:
https://doaj.org/article/0d6e49b3f1674953987b806eee4931dc
Autor:
Marie Auvray Kuentz, Vincent Hautefeuille, Louis de Mestier, Clélia Coutzac, Thierry Lecomte, Victor Nardon, Pascal Artru, Anthony Turpin, Antoine Drouillard, David Malka, My‐Linh Tran‐Minh, Isabelle Trouilloud, Astrid Lièvre, Nicolas Williet, Simon Pernot, Yann Touchefeu, Julien Taieb, Pascal Hammel, Aziz Zaanan
Publikováno v:
International Journal of Cancer
International Journal of Cancer, 2023, ⟨10.1002/ijc.34414⟩
International Journal of Cancer, 2023, ⟨10.1002/ijc.34414⟩
International audience; Pancreatic adenosquamous carcinoma (PASC) account for < 5% of pancreatic malignancies. The efficacy of modern chemotherapy regimens in patients with advanced PASC is unknown. Patients with advanced PASC from 2008 to 2021 were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32839cb13639b6205ba8b4189f0b378c
https://doi.org/10.1002/ijc.34414
https://doi.org/10.1002/ijc.34414
Akademický článek
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Autor:
Clélia Coutzac, Isabelle Trouilloud, Pascal Artru, Julie Henriques, Thérese Masson, Solene Doat, Olivier Bouché, Romain Coriat, Angélique Saint, Valérie Moulin, Dewi Vernerey, Claire Gallois, Christelle De La Fouchardière, David Tougeron, Julien Taieb
Publikováno v:
Clinical Colorectal Cancer. 21:132-140
Regorafenib (R) and trifluridine/tipiracil (FTD/TPI) are of proven efficacy in metastatic colorectal cancer (mCRC) patient's refractory to standard therapies. However, it remains unclear which drug should be administered first.This French observation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3cd94743346593a190619229ac4df5
https://doi.org/10.1016/j.clcc.2021.12.003
https://doi.org/10.1016/j.clcc.2021.12.003
Publikováno v:
European Journal of Cancer. 155:145-154
Human microbiota plays a key role in preserving homeostasis; therefore, alteration in its composition is associated with susceptibility to various diseases. Recent findings suggest that gut microbiota may influence response to cancer treatment, espec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c51e3f46df428348ca0b6be01c84563
https://doi.org/10.1016/j.ejca.2021.06.051
https://doi.org/10.1016/j.ejca.2021.06.051
Autor:
Clélia Coutzac, Frederic Bibeau, Meher Ben Abdelghani, Thomas Aparicio, Romain Cohen, Elodie Coquan, Olivier Dubreuil, Ludovic Evesque, François Ghiringhelli, Stefano Kim, Samuel Lesourd, Cindy Neuzillet, Jean-Marc Phelip, Guillaume Piessen, Philippe Rochigneux, Emmanuelle Samalin, Emilie Soularue, Yann Touchefeu, David Tougeron, Aziz Zaanan, Christelle de la Fouchardière
Publikováno v:
Digestive and Liver Disease
Digestive and Liver Disease, 2022, 54 (10), pp.1335-1341. ⟨10.1016/j.dld.2022.07.008⟩
Digestive and Liver Disease, 2022, 54 (10), pp.1335-1341. ⟨10.1016/j.dld.2022.07.008⟩
International audience; Background: Immune checkpoint inhibitors (ICI) targeting Programmed death-1 (PD-1) have shown their efficacy in advanced MSI/dMMR (microsatellite instability/deficient mismatch repair) tumors. The MSI/dMMR status predicts clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54d5c46065bce3549e79b161db7c16c
https://hal.science/hal-03837196/file/PIIS1590865822005916.pdf
https://hal.science/hal-03837196/file/PIIS1590865822005916.pdf
