Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Cläre von Neubeck"'
Autor:
Teresa Bernardo, Carina Behrends, Diana Klein, Anna Kuntze, Beate Timmermann, Cläre von Neubeck
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
High-precision radiotherapy with proton beams is frequently used in the management of aggressive soft tissue sarcoma (STS) and is often combined with doxorubicin (Dox), the first-line chemotherapy for STS. However, current treatment approaches contin
Externí odkaz:
https://doaj.org/article/3c6f5298fa2548b6807fcc36329e7661
Autor:
Teresa Bernardo, Anna Kuntze, Diana Klein, Feline Heinzelmann, Beate Timmermann, Cläre von Neubeck
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12833 (2023)
Surgery, radiotherapy, and chemotherapy are essential treatment modalities to target cancer cells, but they frequently cause damage to the normal tissue, potentially leading to side effects. As proton beam radiotherapy (PBT) can precisely spare norma
Externí odkaz:
https://doaj.org/article/61a2aea803d04296bcbfa50fb88ca14f
Autor:
Moritz Schneider, Elisabeth Bodenstein, Johanna Bock, Antje Dietrich, Sebastian Gantz, Lena Heuchel, Mechthild Krause, Armin Lühr, Cläre von Neubeck, Sindi Nexhipi, Michael Schürer, Falk Tillner, Elke Beyreuther, Theresa Suckert, Johannes Richard Müller
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Background and purposeProton therapy has become a popular treatment modality in the field of radiooncology due to higher spatial dose conformity compared to conventional radiotherapy, which holds the potential to spare normal tissue. Nevertheless, un
Externí odkaz:
https://doaj.org/article/518615c485cd466f9c02ecd307035778
Autor:
Annett Linge, Stefan Schmidt, Fabian Lohaus, Constanze Krenn, Anna Bandurska-Luque, Ivan Platzek, Cläre von Neubeck, Steffen Appold, Alexander Nowak, Volker Gudziol, Frank Buchholz, Gustavo B. Baretton, Michael Baumann, Steffen Löck, Mechthild Krause
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 16, Iss , Pp 40-47 (2019)
Objective: To independently validate the impact of tumour volume, p16 status, cancer stem cell (CSC) marker expression and hypoxia-associated gene signatures as potential prognostic biomarkers for patients with locally advanced head and neck squamous
Externí odkaz:
https://doaj.org/article/54fe9a0255ea45209a2d0abe7e60fd88
Autor:
Theresa Suckert, Elke Beyreuther, Johannes Müller, Behnam Azadegan, Matthias Meinhardt, Felix Raschke, Elisabeth Bodenstein, Cläre von Neubeck, Armin Lühr, Mechthild Krause, Antje Dietrich
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Radiation-induced late side effects such as cognitive decline and normal tissue complications can severely affect quality of life and outcome in long-term survivors of brain tumors. Proton therapy offers a favorable depth-dose deposition with the pot
Externí odkaz:
https://doaj.org/article/56f98a3d85434da3b47291c435e8b163
Autor:
René Günther, Arun Pal, Chloe Williams, Vitaly L. Zimyanin, Maria Liehr, Cläre von Neubeck, Mechthild Krause, Mrudula G. Parab, Susanne Petri, Norman Kalmbach, Stefan L. Marklund, Jared Sterneckert, Peter Munch Andersen, Florian Wegner, Jonathan D. Gilthorpe, Andreas Hermann
Publikováno v:
Cells, Vol 11, Iss 7, p 1246 (2022)
Little is known about the early pathogenic events by which mutant superoxide dismutase 1 (SOD1) causes amyotrophic lateral sclerosis (ALS). This lack of mechanistic understanding is a major barrier to the development and evaluation of efficient thera
Externí odkaz:
https://doaj.org/article/a384eecc4dc6440ea19379b4d2551e7d
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 9, Iss C, Pp 35-41 (2018)
Externí odkaz:
https://doaj.org/article/ec9eb84848f446ef8be1d738a9a02ae9
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2616 (2018)
The biomarker for DNA double stand breaks, gammaH2AX (γH2AX), holds a high potential as an intrinsic radiosensitivity predictor of tumors in clinical practice. Here, two published γH2AX foci datasets from in and ex vivo exposed human head and neck
Externí odkaz:
https://doaj.org/article/d7a58772ac864751a2ef68781f88dc8e
Autor:
Mechthild Krause, Michael Baumann, Jens Overgaard, Jan Alsner, Anna Dubrovska, Howard D. Thames, Gustavo B. Baretton, Daniela E. Aust, Frank Buchholz, Daniel Zips, Stefan Welz, Stephanie E. Combs, Steffi Pigorsch, Claus Belka, Christine Bayer, Anca-Ligia Grosu, Melanie Avlar, Claus Rödel, Panagiotis Balermpas, Martin Stuschke, Ali Sak, Volker Budach, Inge Tinhofer, Jürgen Debus, Amir Abdollahi, Martin Jütz, Cläre von Neubeck, Fabian Lohaus, Alexander Nowak, Volker Gudziol, Steffen Löck, Annett Linge
Correlation of tumor hypoxia using nanoString vs PCR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3480179309c7efe8655fcfbf77a5ecbb
https://doi.org/10.1158/1078-0432.22457088
https://doi.org/10.1158/1078-0432.22457088
Autor:
Mechthild Krause, Michael Baumann, Jens Overgaard, Jan Alsner, Anna Dubrovska, Howard D. Thames, Gustavo B. Baretton, Daniela E. Aust, Frank Buchholz, Daniel Zips, Stefan Welz, Stephanie E. Combs, Steffi Pigorsch, Claus Belka, Christine Bayer, Anca-Ligia Grosu, Melanie Avlar, Claus Rödel, Panagiotis Balermpas, Martin Stuschke, Ali Sak, Volker Budach, Inge Tinhofer, Jürgen Debus, Amir Abdollahi, Martin Jütz, Cläre von Neubeck, Fabian Lohaus, Alexander Nowak, Volker Gudziol, Steffen Löck, Annett Linge
Multivariate analyses of hypoxia-gene signatures and additional prognostic factors assessed for all patients. HR = hazard ratio; 95% CI = 95 percent confidence interval; ECE = extracapsular extension.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8386ca0825359f75b753c5e8e9ae50e6
https://doi.org/10.1158/1078-0432.22457091.v1
https://doi.org/10.1158/1078-0432.22457091.v1