Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cláudio Canetti"'
Proinflammatory Responses of Heme in Alveolar Macrophages: Repercussion in Lung Hemorrhagic Episodes
Autor:
Rafael L. Simões, Maria Augusta Arruda, Cláudio Canetti, Carlos H. Serezani, Iolanda M. Fierro, Christina Barja-Fidalgo
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Clinical and experimental observations have supported the notion that free heme released during hemorrhagic and hemolytic episodes may have a major role in lung inflammation. With alveolar macrophages (AM) being the main line of defense in lung envir
Externí odkaz:
https://doaj.org/article/1ec1bcec84304d59862b6f436db399eb
Autor:
Giovanna N Pezzella-Ferreira, Camila R R Pão, Isaac Bellas, Tatiana Luna-Gomes, Valdirene S Muniz, Ligia A Paiva, Natalia R T Amorim, Claudio Canetti, Patricia T Bozza, Bruno L Diaz, Christianne Bandeira-Melo
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1011812 (2024)
Identifying new molecular therapies targeted at the severe hepatic fibrosis associated with the granulomatous immune response to Schistosoma mansoni infection is essential to reduce fibrosis-related morbidity/mortality in schistosomiasis. In vitro ce
Externí odkaz:
https://doaj.org/article/1f38e82a060740d7afe731a8ec32d457
Autor:
Amanda Roberta Revoredo Vicentino, Vanderlei da Silva Fraga‐Junior, Matheus Palazzo, Natalia Recardo Amorim Tasmo, Danielle A. S. Rodrigues, Shana Priscila Coutinho Barroso, Sâmila Natiane Ferreira, Anna Cristina Neves‐Borges, Diego Allonso, Marcelo Rosado Fantappié, Julio Scharfstein, Ana Carolina Oliveira, Rosane Vianna‐Jorge, André Macedo Vale, Robson Coutinho‐Silva, Luiz Eduardo Baggio Savio, Claudio Canetti, Claudia Farias Benjamim
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 4, Pp 631-646 (2023)
Abstract The severe acute respiratory syndrome coronavirus 2, the agent of the ongoing coronavirus disease 2019 (COVID‐19) pandemic, has spread worldwide since it was first identified in November 2019 in Wuhan, China. Since then, progress in pathog
Externí odkaz:
https://doaj.org/article/0d44ed7490b24374acc447aaa243ed8c
Autor:
Rafael F. Guilherme, José Bruno N.F. Silva, Ingrid Waclawiack, Vanderlei S. Fraga-Junior, Thaís O. Nogueira, Cyntia Pecli, Carlla A. Araújo-Silva, Nathalia S. Magalhães, Felipe S. Lemos, Carlos A. Bulant, Pablo J. Blanco, Rafaela Serra, Erik Svensjö, Júlio Scharfstein, João A. Moraes, Claudio Canetti, Claudia F. Benjamim
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPulmonary fibrosis is a destructive, progressive disease that dramatically reduces life quality of patients, ultimately leading to death. Therapeutic regimens for pulmonary fibrosis have shown limited benefits, hence justifying the effort
Externí odkaz:
https://doaj.org/article/07b139003d154214b4f56cea93ea5926
Autor:
Paula Alvarenga Borges, Ingrid Waclawiak, Janaína Lima Georgii, Vanderlei da Silva Fraga-Junior, Janaína Figueiredo Barros, Felipe Simões Lemos, Thaís Russo-Abrahão, Elvira Maria Saraiva, Christina M. Takiya, Robson Coutinho-Silva, Carmen Penido, Claudia Mermelstein, José Roberto Meyer-Fernandes, Fábio B. Canto, Josiane Sabbadini Neves, Paulo A. Melo, Claudio Canetti, Claudia Farias Benjamim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic wounds are a public health problem worldwide, especially those related to diabetes. Besides being an enormous burden to patients, it challenges wound care professionals and causes a great financial cost to health system. Considering the absen
Externí odkaz:
https://doaj.org/article/05ea3e3283e24c8abf88a07d23bfa717
Autor:
Natália R. T. Amorim, Glaucia Souza-Almeida, Tatiana Luna-Gomes, Patricia T. Bozza, Claudio Canetti, Bruno L. Diaz, Clarissa M. Maya-Monteiro, Christianne Bandeira-Melo
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Eosinophils are key regulators of adipose tissue homeostasis, thus characterization of adipose tissue-related molecular factors capable of regulating eosinophil activity is of great interest. Leptin is known to directly activate eosinophils in vitro,
Externí odkaz:
https://doaj.org/article/aefb7cfaba8e48aaa846a6779fe72ee4
Autor:
Mariana M Chaves, Debora A Sinflorio, Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Aline Cristina Abreu Moreira-Souza, Thuany Prado Rangel, Claudia L M Silva, Maria Bellio, Claudio Canetti, Robson Coutinho-Silva
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007887 (2019)
Leishmaniasis is a neglected tropical disease affecting millions of individuals worldwide. P2X7 receptor has been linked to the elimination of Leishmania amazonensis. Biological responses evoked by P2X7 receptor activation have been well-documented,
Externí odkaz:
https://doaj.org/article/aa7a275cf206443fb3d0cc99fa606955
Autor:
Natália R. T. Amorim, Tatiana Luna-Gomes, Marcos Gama-Almeida, Glaucia Souza-Almeida, Claudio Canetti, Bruno L. Diaz, Peter F. Weller, Patricia Torres Bozza, Clarissa M. Maya-Monteiro, Christianne Bandeira-Melo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure. Leptin also regulates the immune response by controlling activation of immunomodulato
Externí odkaz:
https://doaj.org/article/9919567f1d6b4bc0a1f8428ccbfdcb18
Autor:
Maria Luiza Thorstenberg, Marcos Vinícius Rangel Ferreira, Natália Amorim, Claudio Canetti, Fernanda B. Morrone, José Carlos Alves Filho, Robson Coutinho-Silva
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The release of damage-associated molecular patterns, including uridine triphosphate (UTP) and adenosine triphosphate (ATP) to the extracellular milieu is a key component of innate immune response to infection. Previously, we showed that macrophage in
Externí odkaz:
https://doaj.org/article/39299c775f4d41bf92060dc8043fb106
Autor:
Carla da S. Pinheiro, Ana Paula T. Monteiro, Fabiano F. Dutra, Marcelo T. Bozza, Marc Peters-Golden, Claudia F. Benjamim, Claudio Canetti
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
TLRs recognize a broad spectrum of microorganism molecules, triggering a variety of cellular responses. Among them, phagocytosis is a critical process for host defense. Leukotrienes (LTs), lipid mediators produced from 5-lipoxygenase (5-LO) enzyme, i
Externí odkaz:
https://doaj.org/article/97d92a8d28ed4d9486dd9c3e955821f5